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KXD1 and DYRK2
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
KXD1
DYRK2
Gene Name
KxDL motif containing 1
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
BLOC-1 Complex
Ubiquitin Ligase Complex
Nucleus
Nucleoplasm
Cytoplasm
Ribonucleoprotein Complex
Molecular Function
Protein Binding
Magnesium Ion Binding
Protein Serine/threonine Kinase Activity
Protein Serine/threonine/tyrosine Kinase Activity
Protein Tyrosine Kinase Activity
Protein Binding
ATP Binding
Manganese Ion Binding
Ubiquitin Binding
Biological Process
Vesicle-mediated Transport
Protein Phosphorylation
Cellular Response To DNA Damage Stimulus
Smoothened Signaling Pathway
Peptidyl-tyrosine Phosphorylation
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Positive Regulation Of Glycogen Biosynthetic Process
Negative Regulation Of NFAT Protein Import Into Nucleus
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
39 interactors:
APPL1
ARHGDIG
C4orf46
CCDC185
CCDC33
CEP170P1
CEP19
CEP63
DYRK2
EWSR1
EXOC5
EXOC7
FXR2
HAUS1
IFT20
ING5
ITSN2
KRT81
LMO3
LNX1
LRRC45
MAP1LC3A
MAP1LC3B
MCRS1
MOB1A
MYH7
NIF3L1
NUDT18
RABGEF1
RNF183
RPL9
STX11
TCEB3B
TPM1
TPM3
UTP6
ZBTB25
ZC4H2
ZNF417
20 interactors:
APP
ATM
DDB1
DYRK4
HIST2H2BE
HIST3H3
IKZF1
KATNA1
KXD1
LZTS2
MDM2
NR1I2
RAD54B
SIAH2
SP100
TERT
UBC
UBR5
WDR62
ZBTB9
Entrez ID
79036
8445
HPRD ID
14526
04606
Ensembl ID
ENSG00000105700
Uniprot IDs
Q9BQD3
Q92630
PDB IDs
3K2L
3KVW
4AZF
Enriched GO Terms of Interacting Partners
?
Actin-myosin Filament Sliding
Muscle Filament Sliding
Organelle Assembly
Actin-mediated Cell Contraction
Actin Filament-based Movement
Membrane Organization
Cellular Response To Nitrogen Starvation
Nucleophagy
Membrane Fusion
Mitochondrion Degradation
Organelle Disassembly
Organelle Organization
Negative Regulation Of Kit Signaling Pathway
Positive Regulation Of Glucocorticoid Receptor Signaling Pathway
DGDP Catabolic Process
DADP Catabolic Process
Positive Regulation Of Heart Rate By Epinephrine
GDP Catabolic Process
Opsin Transport
Autophagic Vacuole Assembly
Ventricular Cardiac Muscle Tissue Morphogenesis
Cardiac Muscle Tissue Development
Ventricular Cardiac Muscle Tissue Development
Cardiac Muscle Tissue Morphogenesis
Macroautophagy
Muscle Contraction
7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process
Muscle Tissue Morphogenesis
Muscle Organ Morphogenesis
Cardiac Ventricle Morphogenesis
Dihydrobiopterin Metabolic Process
Telomere Maintenance
Intracellular Receptor Signaling Pathway
DNA Damage Response, Signal Transduction By P53 Class Mediator
Chromosome Organization
Regulation Of Mitotic Cell Cycle Phase Transition
Signal Transduction In Response To DNA Damage
DNA Metabolic Process
Regulation Of Cell Cycle Phase Transition
Negative Regulation Of Cellular Metabolic Process
Signal Transduction By P53 Class Mediator
Cellular Response To DNA Damage Stimulus
Regulation Of Wnt Signaling Pathway
Cell Cycle
Protein Catabolic Process
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Signal Transduction Involved In DNA Damage Checkpoint
Signal Transduction Involved In Cell Cycle Checkpoint
Regulation Of Mitotic Cell Cycle
Chromatin Organization
Mitotic G1 DNA Damage Checkpoint
Replicative Senescence
Mitotic G1/S Transition Checkpoint
G1 DNA Damage Checkpoint
Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Cell Cycle Process
Positive Regulation Of Cell Cycle Arrest
Microtubule Severing
Negative Regulation Of Cellular Protein Metabolic Process
Regulation Of Cell Cycle Process
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Protein Metabolic Process
Regulation Of Cell Cycle Arrest
Mitotic DNA Damage Checkpoint
Proteolysis Involved In Cellular Protein Catabolic Process
Organelle Organization
Positive Regulation Of Cell Cycle
Cellular Protein Catabolic Process
Protein Ubiquitination
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Mitotic DNA Integrity Checkpoint
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
DNA Repair
Chromatin Modification
Protein Modification By Small Protein Conjugation
Tagcloud
?
better
clinicopathological
closely
december
dual
free
grade
histological
hormone
hundred
ihc
immunohistochemical
involvement
january
lymph
metastasis
node
predict
predictive
prognosis
recurrence
seventy
specificity
stage
status
surgery
ten
underwent
Tagcloud (Difference)
?
better
clinicopathological
closely
december
dual
free
grade
histological
hormone
hundred
ihc
immunohistochemical
involvement
january
lymph
metastasis
node
predict
predictive
prognosis
recurrence
seventy
specificity
stage
status
surgery
ten
underwent
Tagcloud (Intersection)
?