KXD1 and RNF183

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
HPRD (two hybrid)

		KXD1	RNF183
Description		KxDL motif containing 1	ring finger protein 183
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Membrane BLOC-1 Complex Cytoplasmic Side Of Lysosomal Membrane BORC Complex	Lysosome Lysosomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane Cis-Golgi Network Membrane
	Molecular Function	Protein Binding	Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Vesicle-mediated Transport Lysosome Localization Regulation Of Endosome Size Regulation Of Lysosome Size Organelle Transport Along Microtubule	Protein Polyubiquitination Apoptotic Process Protein Ubiquitination Response To Endoplasmic Reticulum Stress Protein Autoubiquitination Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS			Appendicular lean mass ( 33097823)
Interacting Genes		42 interacting genes: APPL1 ARHGDIG C4orf46 CCDC185 CCDC33 CEP170P1 CEP19 CEP63 DYRK2 ELOA ELOA2 EWSR1 EXOC7 FXR2 GABARAPL1 HAUS1 IFT20 ING5 ITSN2 KRT81 LMO3 LNX1 LRRC45 MAB21L3 MAP1LC3A MAP1LC3B MCRS1 MOB1A MYH7 NIF3L1 NUDT18 RABGEF1 RNF183 RPL9 STX11 TCEA2 TPM1 TPM3 UTP6 ZBTB25 ZC4H2 ZNF417	12 interacting genes: APP BCL2 BCL2L1 EWSR1 FATE1 FBP1 GOPC IFFO1 KXD1 TAX1BP3 UBE2K UBE2W
Entrez ID		79036	138065
HPRD ID		14526	10082
Ensembl ID		ENSG00000105700	ENSG00000165188
Uniprot IDs		Q9BQD3	Q96D59
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Elongin Complex Muscle Thin Filament Tropomyosin Ciliary Basal Body Centrosome Transcription Elongation By RNA Polymerase II Cytoskeleton Protein Binding DNA-templated Transcription Elongation Autophagosome Maturation Autophagosome Membrane Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Mitophagy Muscle Filament Sliding Spindle Pole	Dendritic Cell Apoptotic Process Negative Regulation Of Protein Localization Negative Regulation Of Dendritic Cell Apoptotic Process BH3 Domain Binding Bcl-2 Family Protein Complex Negative Regulation Of Protein Localization To Cell Surface Ubiquitin Protein Ligase Binding Identical Protein Binding Negative Regulation Of Anoikis Programmed Cell Death Involved In Cell Development Release Of Cytochrome C From Mitochondria Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Intrinsic Apoptotic Signaling Pathway Neuron Maturation Negative Regulation Of Signaling Negative Regulation Of Signal Transduction Regulation Of Protein Localization Negative Regulation Of Cell Communication Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Anoikis Ubiquitin Conjugating Enzyme Activity Channel Activity Mitochondrial Outer Membrane Regulation Of Protein Localization To Cell Surface Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Growth Regulation Of Neuron Apoptotic Process Regulation Of Response To Calcium Ion Regulation Of Glycolytic Process Amylin Binding Positive Regulation Of Toll Signaling Pathway Response To Peptide Cellular Response To CAMP Response To Cytokine Epithelial Cell Apoptotic Process Negative Regulation Of Retinal Cell Programmed Cell Death Negative Regulation Of Cellular PH Reduction Ovarian Follicle Development Response To Gamma Radiation Leukocyte Apoptotic Process Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Leukocyte Apoptotic Process Apoptotic Process In Bone Marrow Cell Negative Regulation Of Anion Channel Activity Regulation Of Mitochondrial Membrane Permeability Protein Polyubiquitination
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