HROB and MAPRE3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		HROB	MAPRE3
Description		homologous recombination factor with OB-fold	microtubule associated protein RP/EB family member 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Chromosome Site Of DNA Damage	Cytoplasm Microtubule Organizing Center Cytoskeleton Microtubule Cytoplasmic Microtubule Microtubule Cytoskeleton Midbody Microtubule Plus-end Perinuclear Region Of Cytoplasm Spindle Midzone Neuron To Neuron Synapse Mitotic Spindle Astral Microtubule End Microtubule End
	Molecular Function	DNA Binding Single-stranded DNA Binding Protein Binding	Protein Binding Microtubule Binding Identical Protein Binding Protein Serine/threonine Kinase Activator Activity Microtubule Plus-end Binding Protein Serine/threonine Kinase Binding
	Biological Process	Recombinational Repair DNA Synthesis Involved In DNA Repair DNA Repair DNA Recombination DNA Damage Response Female Gamete Generation Interstrand Cross-link Repair Male Gamete Generation DNA Biosynthetic Process	Intracellular Protein Localization Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Microtubule Polymerization Protein Localization To Microtubule Positive Regulation Of DNA-templated Transcription Behavioral Response To Cocaine Spindle Assembly Cell Division Positive Regulation Of Dendritic Spine Morphogenesis
Pathways
Drugs
Diseases
GWAS			Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Estimated glomerular filtration rate in non-diabetics ( 31451708) Left–right brain asymmetry ( 33723403) Lymphocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Post bronchodilator FEV1/FVC ratio ( 26634245) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		5 interacting genes: MAPRE3 PIK3R3 PRMT1 TRIM55 TRIM63	56 interacting genes: ANKRD1 APC2 AURKA AURKB C20orf202 CCSER1 CHRDL2 CLASP1 CRTAC1 DCTN2 DDIT4L DOK4 EIF4E2 FAM161B FOXD4L1 FOXD4L4 FXR2 GTF2F2 GTSE1 HROB IKZF1 JUN KIF19 KLHDC7B KNSTRN LAP3 LHX4 LMO2 MAPRE2 MARCHF7 MEOX2 MRPL12 PDE4DIP PICK1 POU4F1 PSMA1 PSMB1 PSRC1 RAB1A REL SDCBP SIAH1 SLAIN1 SPDYE2 SPDYE2B SPMIP10 SPMIP2 TLE5 TRAIP TRIM14 TXN2 YAF2 ZC2HC1A ZC2HC1C ZNF526 ZNF547
Entrez ID		78995	22924
HPRD ID		08825	16156
Ensembl ID		ENSG00000125319	ENSG00000084764
Uniprot IDs		Q8N3J3	Q9UPY8
PDB IDs			1WYO 3CO1 3JAK 3JAL 3JAR 3TQ7 7SJ9
Enriched GO Terms of Interacting Partners?		Microtubule Regulation Of Hemoglobin Biosynthetic Process Protein-arginine Omega-N Monomethyltransferase Activity N-methyltransferase Activity Mitogen-activated Protein Kinase P38 Binding Response To Methionine Histone H4R3 Methyltransferase Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone H4 Methyltransferase Activity GATOR1 Complex Binding Cellular Response To Methionine Positive Regulation Of Hemoglobin Biosynthetic Process Peptidyl-arginine Methylation 1-phosphatidylinositol-3-kinase Regulator Activity Mitotic Spindle Astral Microtubule End Microtubule End Diapedesis Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Skeletal Muscle Atrophy Skeletal Muscle Adaptation Striated Muscle Atrophy Protein-arginine N-methyltransferase Activity Membraneless Organelle Assembly Phosphatidylinositol 3-kinase Complex Phosphatidylinositol 3-kinase Complex, Class IA Neuron To Neuron Synapse Muscle Atrophy 1-phosphatidylinositol-3-kinase Activity Immune Response Methylosome Protein Methyltransferase Activity Titin Binding Contractile Muscle Fiber	Regulation Of Microtubule Polymerization Or Depolymerization Microtubule-based Process Microtubule Cytoskeleton Organization Spindle Organization Regulation Of Microtubule Cytoskeleton Organization Cytoplasmic Microtubule Microtubule Plus-end Microtubule Cytoskeleton Regulation Of Microtubule-based Process Positive Regulation Of Microtubule Polymerization Cytoskeleton Spindle Microtubule Cytoskeleton Organization Microtubule Microtubule Organizing Center Plasma Membrane Bounded Cell Projection Organization Microtubule Plus-end Binding Cytoplasmic Microtubule Organization Regulation Of Microtubule Polymerization Spindle Midzone Protein Binding Cell Projection Organization Chromosome Passenger Complex Positive Regulation Of Protein Polymerization Microtubule Binding Kinetochore Mitotic Spindle Organization Spindle Assembly Positive Regulation Of Supramolecular Fiber Organization Regulation Of Microtubule Depolymerization Regulation Of Supramolecular Fiber Organization Regulation Of Cytoskeleton Organization Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Epithelial Cell Migration Cilium Disassembly Protein Localization To Cytoskeleton Astral Microtubule Organization Beta-catenin Destruction Complex Regulation Of Signal Transduction By P53 Class Mediator Microtubule Cytoskeleton Organization Involved In Mitosis Negative Regulation Of Interferon-beta Production Positive Regulation Of Organelle Organization Regulation Of Organelle Organization Regulation Of Epithelial Cell Migration
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