BRPF1 and PBXIP1

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		BRPF1	PBXIP1
Gene Name		bromodomain and PHD finger containing, 1	pre-B-cell leukemia homeobox interacting protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm MOZ/MORF Histone Acetyltransferase Complex	Nucleus Cytosol Microtubule
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding	Transcription Corepressor Activity Protein Binding
	Biological Process	Chromatin Organization Transcription, DNA-templated Histone H3 Acetylation Positive Regulation Of Transcription, DNA-templated	Multicellular Organismal Development Cell Differentiation Negative Regulation Of Transcription, DNA-templated
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS			Prostate cancer ( 23535732)
Protein-Protein Interactions		4 interactors: GTF2H1 HIST2H3C MEAF6 PBXIP1	19 interactors: BRPF1 CCDC53 CCDC85B CCNC DAXX DEF6 DPPA2 GMCL1 GRB2 MDFI MORF4L1 PCBD2 PRKAA2 SGTA TSNAX UBQLN1 UBQLN4 ZMYND8 ZZZ3
Entrez ID		7862	57326
HPRD ID		03875	17823
Ensembl ID		ENSG00000156983	ENSG00000163346
Uniprot IDs		P55201	B4E1J0 Q96AQ6
PDB IDs		2D9E 2RS9 2X35 2X4W 2X4X 2X4Y 3L42 3MO8
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Gene Expression, Epigenetic Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression Histone H3-K14 Acetylation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Histone H4-K12 Acetylation Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process DNA Methylation On Cytosine Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H2A Acetylation Chromatin Silencing At RDNA Nucleotide-excision Repair, DNA Damage Removal Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter 7-methylguanosine MRNA Capping Transcription From RNA Polymerase I Promoter Chromatin Silencing 7-methylguanosine RNA Capping Transcription-coupled Nucleotide-excision Repair Histone H3 Acetylation Positive Regulation Of Viral Transcription Histone H4 Acetylation Regulation Of Metabolic Process DNA Methylation Transcription Elongation From RNA Polymerase II Promoter Gene Expression DNA Metabolic Process Regulation Of Viral Transcription Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Viral Process DNA-templated Transcription, Termination Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process DNA-templated Transcription, Elongation DNA Modification Nucleotide-excision Repair Gene Silencing Negative Regulation Of Biosynthetic Process Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation	Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Regulation Of Metabolic Process RNA Biosynthetic Process RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Gene Expression Chromatin Organization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Activation Of JUN Kinase Activity Cellular Nitrogen Compound Metabolic Process Cellular Response To Stress Cellular Macromolecule Biosynthetic Process Chromosome Organization Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Chromatin Modification Positive Regulation Of JUN Kinase Activity Biosynthetic Process Regulation Of JUN Kinase Activity JNK Cascade Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Protein Metabolic Process Histone Modification Embryonic Placenta Development Histone Acetylation Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of JNK Cascade Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Heterooligomerization Positive Regulation Of Stress-activated MAPK Cascade Protein Acetylation Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Protein Metabolic Process Activation Of MAPK Activity Insulin Receptor Signaling Pathway Carnitine Shuttle Tetrahydrobiopterin Biosynthetic Process Regulation Of JNK Cascade
Tagcloud ?		acetylates acetyllysine bonding bromodomain calculate directs discrete energies finger h2a h2ak5ac h2b h3k14ac h4k12ac hat heaf6 histones ing5 monocytic moz outline perturbation phd pocket quaternary selects tails titration translationally
Tagcloud (Difference) ?		acetylates acetyllysine bonding bromodomain calculate directs discrete energies finger h2a h2ak5ac h2b h3k14ac h4k12ac hat heaf6 histones ing5 monocytic moz outline perturbation phd pocket quaternary selects tails titration translationally
Tagcloud (Intersection) ?