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BTG2 and PRMT1
Number of citations of the paper that reports this interaction (PubMedID
16782888
)
55
Data Source:
BioGRID
(pull down, biochemical)
HPRD
(in vitro)
BTG2
PRMT1
Description
BTG anti-proliferation factor 2
protein arginine methyltransferase 1
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Extracellular Exosome
Nucleus
Nucleoplasm
Cytoplasm
Lysosome
Lysosomal Membrane
Cytosol
Membrane
Methylosome
Molecular Function
Transcription Corepressor Activity
Protein Binding
RNA Binding
Protein Binding
Methyltransferase Activity
N-methyltransferase Activity
Protein Methyltransferase Activity
Methyl-CpG Binding
Protein-arginine N-methyltransferase Activity
Transferase Activity
Enzyme Binding
Protein-arginine Omega-N Monomethyltransferase Activity
Protein-arginine Omega-N Asymmetric Methyltransferase Activity
Histone Methyltransferase Activity
Identical Protein Binding
Histone H4R3 Methyltransferase Activity
Mitogen-activated Protein Kinase P38 Binding
GATOR1 Complex Binding
Histone H4 Methyltransferase Activity
S-adenosyl-L-methionine Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
DNA Repair
DNA Damage Response
Neuroblast Proliferation
Negative Regulation Of Neuroblast Proliferation
Negative Regulation Of Cell Population Proliferation
Associative Learning
Response To Mechanical Stimulus
Anterior/posterior Pattern Specification
Negative Regulation Of Translation
Dentate Gyrus Development
Central Nervous System Neuron Development
Neuron Differentiation
Neuron Projection Development
Skeletal Muscle Cell Differentiation
Negative Regulation Of Apoptotic Process
Response To Peptide Hormone
Negative Regulation Of Neuron Apoptotic Process
Response To Electrical Stimulus
Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening
Neural Precursor Cell Proliferation
Cellular Response To Phorbol 13-acetate 12-myristate
Double-strand Break Repair Via Homologous Recombination
In Utero Embryonic Development
Chromatin Remodeling
Regulation Of DNA-templated Transcription
Protein Methylation
DNA Damage Response
Cell Surface Receptor Signaling Pathway
Positive Regulation Of Cell Population Proliferation
RNA Splicing
Negative Regulation Of Translation
Peptidyl-arginine Methylation
Viral Protein Processing
BMP Signaling Pathway
Regulation Of BMP Signaling Pathway
Negative Regulation Of BMP Signaling Pathway
Neuron Projection Development
Cellular Response To Nutrient Levels
Methylation
Cellular Response To Amino Acid Starvation
TORC1 Signaling
Positive Regulation Of Erythrocyte Differentiation
Regulation Of Megakaryocyte Differentiation
Negative Regulation Of Megakaryocyte Differentiation
Positive Regulation Of Translation
Negative Regulation Of Translational Initiation
Negative Regulation Of JNK Cascade
Positive Regulation Of Hemoglobin Biosynthetic Process
Cardiac Muscle Tissue Development
Protein Homooligomerization
Cellular Response To Methionine
Protein Localization To Lysosome
Membraneless Organelle Assembly
Positive Regulation Of P38MAPK Cascade
Negative Regulation Of TORC1 Signaling
Positive Regulation Of TORC1 Signaling
Positive Regulation Of Double-strand Break Repair Via Homologous Recombination
Negative Regulation Of Double-strand Break Repair Via Homologous Recombination
Pathways
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
RMTs methylate histone arginines
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Extra-nuclear estrogen signaling
Estrogen-dependent gene expression
Maturation of nucleoprotein
Drugs
S-adenosyl-L-homocysteine
Diseases
GWAS
Immature fraction of reticulocytes (
27863252
32888494
)
Mean corpuscular hemoglobin (
27863252
32888494
)
Mean corpuscular volume (
27863252
32888494
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Red blood cell count (
27863252
32888494
)
Red cell distribution width (
27863252
28957414
32888494
)
Schizophrenia (
29483656
)
Interacting Genes
16 interacting genes:
CCNB1
CDK1
CNOT7
CNOT8
HOXB9
HOXC8
MAPK14
MAPK3
PICK1
PIN1
PRKCA
PRMT1
SKP2
SMAD1
SMAD9
SRA1
165 interacting genes:
AR
ARPC3
ASH2L
AXIN1
BRCA1
BTG1
BTG2
C4orf17
CAPRIN1
CDC37
CEBPA
CEP162
CIRBP
CNOT8
COIL
DAXX
DCAF16
DCAF8
DHX9
EP300
ESR1
EWSR1
FAM83D
FAM9A
FBL
FBXL17
FBXO7
FGF2
FLII
FUS
GLI1
GPATCH2L
GRHL3
GRIP1
H3C1
H4C1
H4C14
H4C16
HABP4
HNF4A
HNRNPA1
HNRNPA3
HNRNPK
HNRNPR
HNRNPU
HNRNPUL1
HROB
IDH3B
IFNAR1
IGSF21
ILF3
KHDRBS1
KHDRBS2
KHDRBS3
LRIF1
MAP3K5
MBD2
MBP
MECOM
MED31
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR138-1
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR206
MIR20A
MIR20B
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR34A
MIR34C
MIR363
MIR451A
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MLST8
NCOA1
NCOA2
NCOA3
NOL4
NRIP1
NTAQ1
OFCC1
PPARA
PPDPF
PRMT8
QKI
RBM15
RELA
RNF187
RPL37A
RPS29
RUNX1
S100A8
SAMD3
SHLD1
SIRT1
SPAG8
SPEG
SPSB1
SPSB2
SRSF1
STAT1
STAT5A
STUB1
SUPT5H
SYNCRIP
TBX6
TERF2
THRB
TK1
TOPORS
TP53
TRIM48
TUBB
UBE4B
USP11
VHL
VPS72
WDFY3
WDR33
YLPM1
YWHAG
ZBTB14
ZCCHC12
ZMYM5
ZNF451
Entrez ID
7832
3276
HPRD ID
03357
04257
Ensembl ID
ENSG00000159388
ENSG00000126457
Uniprot IDs
P78543
Q99873
PDB IDs
3DJU
3E9V
6NT2
Enriched GO Terms of Interacting Partners
?
Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Metabolic Process
Positive Regulation Of Cell Population Proliferation
Regulation Of RNA Metabolic Process
Regulation Of Primary Metabolic Process
Regulation Of Cell Population Proliferation
Regulation Of Macromolecule Metabolic Process
Regulation Of Gene Expression
Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Metabolic Process
Positive Regulation Of Biosynthetic Process
Cyclin B1-CDK1 Complex
Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway
BMP Signaling Pathway
Positive Regulation Of RNA Metabolic Process
Positive Regulation Of Cardiac Muscle Cell Proliferation
Regulation Of Transcription By RNA Polymerase II
Response To Stress
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Macromolecule Metabolic Process
Nucleoplasm
Positive Regulation Of Mitochondrial ATP Synthesis Coupled Electron Transport
Positive Regulation Of Heart Growth
Regulation Of Cardiac Muscle Cell Proliferation
Negative Regulation Of Metabolic Process
Intracellular Signaling Cassette
Positive Regulation Of Organ Growth
Regulation Of MRNA Metabolic Process
CCR4-NOT Core Complex
G2/M Transition Of Mitotic Cell Cycle
Mitogen-activated Protein Kinase P38 Binding
SMAD Protein Complex
Nucleus
Cytosol
Cell Cycle G2/M Phase Transition
Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway
Heteromeric SMAD Protein Complex
Regulation Of MRNA Stability
Response To Mechanical Stimulus
Regulation Of Heart Growth
Ventricular Cardiac Muscle Cell Development
Nucleic Acid Metabolic Process
Regulation Of RNA Stability
Mitotic Nuclear Membrane Disassembly
Poly(A)-specific Ribonuclease Activity
G1/S Transition Of Mitotic Cell Cycle
MiRNA-mediated Post-transcriptional Gene Silencing
Regulatory NcRNA-mediated Post-transcriptional Gene Silencing
RISC Complex
Post-transcriptional Gene Silencing
Regulatory NcRNA-mediated Gene Silencing
MRNA Base-pairing Post-transcriptional Repressor Activity
Post-transcriptional Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
MRNA 3'-UTR Binding
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Metabolic Process
MiRNA-mediated Gene Silencing By Inhibition Of Translation
Regulation Of Gene Expression
Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Translation
Regulation Of Macromolecule Metabolic Process
Regulation Of Metabolic Process
Extracellular Vesicle
Regulation Of Translation
MiRNA-mediated Gene Silencing By MRNA Destabilization
Regulation Of MRNA Metabolic Process
Negative Regulation Of Developmental Process
Regulation Of Angiogenesis
Negative Regulation Of Angiogenesis
Negative Regulation Of Vasculature Development
Regulation Of Vasculature Development
Negative Regulation Of Protein Metabolic Process
Regulation Of MRNA Stability
Regulation Of Blood Vessel Endothelial Cell Migration
Negative Regulation Of Vascular Endothelial Growth Factor Production
Regulation Of RNA Stability
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Positive Regulation Of RNA Metabolic Process
Positive Regulation Of MRNA Catabolic Process
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Developmental Process
Positive Regulation Of Metabolic Process
Positive Regulation Of MRNA Metabolic Process
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of Primary Metabolic Process
Regulation Of Programmed Cell Death
Regulation Of Multicellular Organismal Development
MRNA Destabilization
Negative Regulation Of Cell Differentiation
Regulation Of Anatomical Structure Morphogenesis
Regulation Of Cell Differentiation
Negative Regulation Of Cytokine Production
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