DAP3 and THRA

Number of citations of the paper that reports this interaction (PubMedID 10903152)
34

Data Source:
BioGRID (pull down)

		DAP3	THRA
Description		death associated protein 3	thyroid hormone receptor alpha
Image
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Mitochondrial Ribosome Mitochondrial Small Ribosomal Subunit Ribosome Small Ribosomal Subunit Ribonucleoprotein Complex	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol RNA Polymerase II Transcription Regulator Complex
	Molecular Function	Nucleotide Binding RNA Binding Structural Constituent Of Ribosome GTPase Activity Protein Binding GTP Binding Hydrolase Activity	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Nuclear Receptor Activity Protein Binding Zinc Ion Binding TBP-class Protein Binding Protein Domain Specific Binding Chromatin DNA Binding Sequence-specific DNA Binding Protein-containing Complex Binding Metal Ion Binding Thyroid Hormone Binding General Transcription Initiation Factor Binding
	Biological Process	Apoptotic Process Apoptotic Mitochondrial Changes Mitochondrial Translation Apoptotic Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II Cartilage Condensation Ossification Thyroid Hormone Receptor Signaling Pathway Regulation Of Thyroid Hormone Receptor Signaling Pathway Positive Regulation Of Thyroid Hormone Receptor Signaling Pathway Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Learning Or Memory Regulation Of Heart Contraction Female Courtship Behavior Response To Cold Hormone-mediated Signaling Pathway Animal Organ Morphogenesis Negative Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Cell Differentiation Erythrocyte Differentiation Thyroid Gland Development Regulation Of Myeloid Cell Apoptotic Process MRNA Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Positive Regulation Of Female Receptivity Positive Regulation Of Transcription By RNA Polymerase II Retinoic Acid Receptor Signaling Pathway Regulation Of Lipid Catabolic Process Type I Pneumocyte Differentiation Positive Regulation Of Cold-induced Thermogenesis Negative Regulation Of DNA-templated Transcription Initiation
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control	Nuclear Receptor transcription pathway
Drugs			Liothyronine Levothyroxine Dextrothyroxine Amiodarone Liotrix KB-141 Dronedarone Eprotirome NRP409 Thyroid, porcine
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Asthma ( 31619474) Bipolar disorder ( 31043756) Chronic obstructive pulmonary disease ( 30804561) Pancreatic ductal adenocarcinoma ( 30541042) White blood cell count ( 21738480)
Interacting Genes		15 interacting genes: AHR AR ESR1 ESR2 FADD HIF1A HSP90AA1 NR3C1 PGR PPARA PTEN SLC25A21-AS1 THRA TNFRSF10A TNFRSF25	68 interacting genes: AKAP13 AMOT AMOTL2 ARID5A BTG1 BUB3 C1D CCND1 CD160 CDK7 CEP76 CLIC1 COPS2 CREB1 CREBBP CUL1 DAP3 ESR1 FOXJ1 FUS GRIP1 GTF2B HDAC2 HDAC3 ITGB3BP L3MBTL3 MED1 MED21 MED25 MEF2A MEOX2 MTNR1B NCOA1 NCOA2 NCOA6 NCOR1 NCOR2 NR0B2 NR2F1 NRIP1 NSD1 OASL PML POU2F1 PRKAR1B PRKDC PTGES3 RANBP9 RGN RXRA RXRB RXRG SELENOP SLC16A2 SRC SUV39H1 SYAP1 TACC1 TBL1X TDG TRIM24 TRIM63 TRIP11 TXNRD1 UBE2I YWHAH YWHAQ ZBTB3
Entrez ID		7818	7067
HPRD ID		03646	07185
Ensembl ID		ENSG00000132676	ENSG00000126351
Uniprot IDs		P51398	P10827 Q6FH41
PDB IDs		3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5I 7A5K 7L08 7OG4 7P2E 7PNX 7PNY 7PNZ 7PO0 7PO1 7PO2 7PO3 7QI4 7QI5 7QI6 8ANY 8CSP 8CSQ 8CSR 8CSS 8CST 8CSU 8K2A 8OIR 8OIS 8QRK 8QRL 8QRM 8QRN 8RRI 8XT0 8XT2	1NAV 2H77 2H79 3HZF 3ILZ 3JZB 4LNW 4LNX 7QDT 8RQO
Enriched GO Terms of Interacting Partners?		Nuclear Receptor Activity Estrogen Response Element Binding Nuclear Receptor-mediated Signaling Pathway Transcription Coactivator Binding Intracellular Receptor Signaling Pathway Nuclear Steroid Receptor Activity Hormone-mediated Signaling Pathway Steroid Binding Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Activity Sequence-specific DNA Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of MiRNA Transcription TBP-class Protein Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Lipid Binding Regulation Of MiRNA Metabolic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Apoptotic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Programmed Cell Death Chromatin DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of Biosynthetic Process Positive Regulation Of Metabolic Process Apoptotic Process Intracellular Signal Transduction Programmed Cell Death Cell Death Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Animal Organ Development Enzyme Binding Signal Transduction Estrogen Receptor Signaling Pathway DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein-containing Complex Negative Regulation Of MiRNA Transcription Rhythmic Process Tertiary Branching Involved In Mammary Gland Duct Morphogenesis Regulation Of Nucleobase-containing Compound Metabolic Process Reproductive Behavior Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Nuclear Estrogen Receptor Activity Regulation Of Primary Metabolic Process	Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Nuclear Retinoid X Receptor Binding Nuclear Receptor Binding Regulation Of Primary Metabolic Process Nuclear Retinoic Acid Receptor Binding Nucleoplasm Nuclear Thyroid Hormone Receptor Binding Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Nucleus Positive Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Nuclear Receptor-mediated Signaling Pathway Negative Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Rhythmic Process Transcription Corepressor Activity Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Nuclear Estrogen Receptor Binding Positive Regulation Of Metabolic Process Intracellular Receptor Signaling Pathway Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Chromatin Binding Chromatin Transcription By RNA Polymerase II Hormone-mediated Signaling Pathway DNA-templated Transcription Transcription Coactivator Activity Intracellular Signal Transduction Transcription Coregulator Activity Transcription Regulator Complex
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?