TBX3 and CA8

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TBX3	CA8
Gene Name		T-box 3	carbonic anhydrase VIII
Image
Gene Ontology Annotations	Cellular Component	Nucleus	Cytoplasm
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription RNA Polymerase II Transcription Factor Binding RNA Polymerase II Activating Transcription Factor Binding Protein Binding Sequence-specific DNA Binding	Carbonate Dehydratase Activity Zinc Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Skeletal System Development Blood Vessel Development In Utero Embryonic Development Heart Looping Outflow Tract Morphogenesis Atrioventricular Bundle Cell Differentiation Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Cell Aging Positive Regulation Of Cell Proliferation Anterior/posterior Axis Specification, Embryo Organ Morphogenesis Specification Of Organ Position Stem Cell Maintenance Limbic System Development Male Genitalia Development Female Genitalia Development Negative Regulation Of Epithelial Cell Differentiation Mammary Gland Development Luteinizing Hormone Secretion Embryonic Forelimb Morphogenesis Forelimb Morphogenesis Embryonic Digit Morphogenesis Negative Regulation Of Apoptotic Process Negative Regulation Of Myoblast Differentiation Positive Regulation Of Cell Cycle Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Follicle-stimulating Hormone Secretion Mesoderm Morphogenesis Palate Development Ventricular Septum Morphogenesis Branching Involved In Mammary Gland Duct Morphogenesis Mammary Placode Formation Cardiac Muscle Cell Fate Commitment Sinoatrial Node Cell Development Cellular Senescence Positive Regulation Of Stem Cell Proliferation	One-carbon Metabolic Process Phosphatidylinositol-mediated Signaling
Pathways
Drugs
Diseases
GWAS		Blood pressure ( 21572416 21909110) Colorectal cancer ( 23266556) Diastolic blood pressure ( 19430479) Mammographic density ( 22532574) PR interval ( 20062060) Prostate-specific antigen levels ( 21160077) Ventricular conduction ( 21076409)	Cardiac hypertrophy ( 21348951) Obesity-related traits ( 23251661) Response to amphetamines ( 22952603)
Protein-Protein Interactions		3 interactors: AES CA8 TOLLIP	9 interactors: CRX GGA2 HSD17B14 ITPR1 LNX1 LRCH4 MAGED1 SPDL1 TBX3
Entrez ID		6926	767
HPRD ID		03373	00266
Ensembl ID		ENSG00000135111
Uniprot IDs		O15119	P35219
PDB IDs		1H6F	2W2J
Enriched GO Terms of Interacting Partners?			Atrioventricular Bundle Cell Differentiation Follicle-stimulating Hormone Secretion Positive Regulation Of Photoreceptor Cell Differentiation
Tagcloud ?		already alveolar cadherin comprising develops embryo functionally germ give gland highlighting hormone identity immunofluorescence knock lineage luminal mammary milk notably primed reconstitution repressed repressor sensing specification strict ulnar virgin	a8344g anhydrase ataxia autophagic carbonic cerebellar cybrids distinctive encephalomyopathy exhibiting fibres gait harbouring inherited lc3 lifelong maternally merrf mtdna muscular myoclonus phospho ragged retardation staurosporine sts viii waddles wdl
Tagcloud (Difference) ?		already alveolar cadherin comprising develops embryo functionally germ give gland highlighting hormone identity immunofluorescence knock lineage luminal mammary milk notably primed reconstitution repressed repressor sensing specification strict ulnar virgin	a8344g anhydrase ataxia autophagic carbonic cerebellar cybrids distinctive encephalomyopathy exhibiting fibres gait harbouring inherited lc3 lifelong maternally merrf mtdna muscular myoclonus phospho ragged retardation staurosporine sts viii waddles wdl
Tagcloud (Intersection) ?