CA1 and TFCP2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CA1	TFCP2
Gene Name		carbonic anhydrase I	transcription factor CP2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Extracellular Vesicular Exosome	Cellular_component Nucleus
	Molecular Function	Carbonate Dehydratase Activity Zinc Ion Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding
	Biological Process	One-carbon Metabolic Process Bicarbonate Transport Small Molecule Metabolic Process	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		O2/CO2 exchange in erythrocytes Erythrocytes take up carbon dioxide and release oxygen Erythrocytes take up oxygen and release carbon dioxide Reversible hydration of carbon dioxide
Drugs		Methyclothiazide Ethoxzolamide Amlodipine Methocarbamol Bendroflumethiazide Benzthiazide Cyclothiazide Methazolamide Hydroflumethiazide Acetazolamide Dorzolamide Chlorothiazide Zonisamide Hydrochlorothiazide Trichlormethiazide Ethinamate Diazoxide Dichlorphenamide Brinzolamide Quinethazone N-{2-[4-(AMINOSULFONYL)PHENYL]ETHYL}ACETAMIDE 3-[4-(AMINOSULFONYL)PHENYL]PROPANOIC ACID ETHYL 3-[4-(AMINOSULFONYL)PHENYL]PROPANOATE Ellagic Acid
Diseases
GWAS		Blood trace element (Zn levels) ( 23720494)
Protein-Protein Interactions		3 interactors: HSD17B7 MAPK6 TFCP2	62 interactors: ADPRH APBB1 ASAP3 BAG6 C19orf73 CA1 CASP8 CBX8 CCDC94 CDC73 COIL DNAJC27 DNAJC5B DPH1 E2F8 EAF1 EIF5B EPHA10 FAM64A FANCL FARS2 FBXL18 GPANK1 HDAC1 HDAC2 IRAK1BP1 KIAA1598 MAPK1 MAPK14 MAPK8 MOB3C MORF4L1 MRPL11 MRPL40 MVP NABP1 NFE4 NOM1 NPEPL1 PHF1 PITPNM1 PLCB1 POLL POLR3GL PPIG PPP1R1B PPP3R2 PSMD5 RBMS1 RNF2 SDCBP SIN3A STMN2 SUMO1 TCEA2 TDRD1 TRAPPC12 TSPAN12 UBP1 YY1 ZCCHC10 ZCCHC12
Entrez ID		759	7024
HPRD ID		00265	01790
Ensembl ID		ENSG00000133742	ENSG00000135457
Uniprot IDs		P00915	Q12800
PDB IDs		1AZM 1BZM 1CRM 1CZM 1HCB 1HUG 1HUH 1J9W 1JV0 2CAB 2FOY 2FW4 2IT4 2NMX 2NN1 2NN7 3LXE 3W6H 3W6I
Enriched GO Terms of Interacting Partners?			Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process RNA Metabolic Process Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Nitrogen Compound Metabolic Process Cellular Response To DNA Damage Stimulus Cellular Metabolic Process Cellular Response To Stress Chromatin Modification Cellular Protein Metabolic Process Histone Modification Chromatin Organization Negative Regulation Of Gene Expression Cell Cycle Negative Regulation Of Cellular Metabolic Process Protein Metabolic Process Histone Deacetylation Regulation Of Gene Expression Chromosome Organization Regulation Of Metabolic Process Protein Deacetylation TRIF-dependent Toll-like Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Innate Immune Response Activation Of Innate Immune Response Metabolic Process Negative Regulation Of Transcription, DNA-templated Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Stimulus Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Biosynthetic Process Regulation Of Organelle Organization Negative Regulation Of Gene Expression, Epigenetic Cellular Protein Modification Process Negative Regulation Of RNA Biosynthetic Process Peptidyl-amino Acid Modification Toll-like Receptor 4 Signaling Pathway Anatomical Structure Development Anatomical Structure Morphogenesis Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated
Tagcloud ?		accumbens amygdala caudate coeruleus dentate dependence frontal grey gyrus hippocampus hypothalamic infusion intracerebroventricular microl minipumps morphine mrnas nmda nmol nr1 nr2a nr2b nri nucleus opioid osmotic paraventricular putamen tolerance
Tagcloud (Difference) ?		accumbens amygdala caudate coeruleus dentate dependence frontal grey gyrus hippocampus hypothalamic infusion intracerebroventricular microl minipumps morphine mrnas nmda nmol nr1 nr2a nr2b nri nucleus opioid osmotic paraventricular putamen tolerance
Tagcloud (Intersection) ?