CA1

Gene Name		carbonic anhydrase I
Image
Gene Ontology Annotations	Cellular Component	Cytosol Extracellular Vesicular Exosome
	Molecular Function	Carbonate Dehydratase Activity Zinc Ion Binding
	Biological Process	One-carbon Metabolic Process Bicarbonate Transport Small Molecule Metabolic Process
Pathways		O2/CO2 exchange in erythrocytes Erythrocytes take up carbon dioxide and release oxygen Erythrocytes take up oxygen and release carbon dioxide Reversible hydration of carbon dioxide
Drugs		Methyclothiazide Ethoxzolamide Amlodipine Methocarbamol Bendroflumethiazide Benzthiazide Cyclothiazide Methazolamide Hydroflumethiazide Acetazolamide Dorzolamide Chlorothiazide Zonisamide Hydrochlorothiazide Trichlormethiazide Ethinamate Diazoxide Dichlorphenamide Brinzolamide Quinethazone N-{2-[4-(AMINOSULFONYL)PHENYL]ETHYL}ACETAMIDE 3-[4-(AMINOSULFONYL)PHENYL]PROPANOIC ACID ETHYL 3-[4-(AMINOSULFONYL)PHENYL]PROPANOATE Ellagic Acid
Diseases
GWAS		Blood trace element (Zn levels) ( 23720494)
Protein-protein Interactions		3 interactors: HSD17B7 MAPK6 TFCP2
Entrez ID		759
HPRD ID		00265
Ensembl ID		ENSG00000133742
Uniprot IDs		P00915
PDB IDs		1AZM 1BZM 1CRM 1CZM 1HCB 1HUG 1HUH 1J9W 1JV0 2CAB 2FOY 2FW4 2IT4 2NMX 2NN1 2NN7 3LXE 3W6H 3W6I
Enriched GO Terms of Interacting Partners?
Tagcloud ?		accumbens amygdala caudate coeruleus dentate dependence frontal grey gyrus hippocampus hypothalamic infusion intracerebroventricular microl minipumps morphine mrnas nmda nmol nr1 nr2a nr2b nri nucleus opioid osmotic paraventricular putamen tolerance