CA1

Description		carbonic anhydrase 1
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Arylesterase Activity Carbonate Dehydratase Activity Protein Binding Zinc Ion Binding Lyase Activity Hydro-lyase Activity Cyanamide Hydratase Activity Metal Ion Binding
	Biological Process	Response To Fructose
Pathways		Erythrocytes take up carbon dioxide and release oxygen Erythrocytes take up oxygen and release carbon dioxide Reversible hydration of carbon dioxide Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs		Methyclothiazide Topiramate Chlorthalidone Ethoxzolamide Amlodipine Methocarbamol Bendroflumethiazide Benzthiazide Benzthiazide Cyclothiazide Cyclothiazide Methazolamide Hydroflumethiazide Acetazolamide Dorzolamide Chlorothiazide Zonisamide Trichlormethiazide Ethinamate Diazoxide Diclofenamide Brinzolamide Quinethazone N-{2-[4-(AMINOSULFONYL)PHENYL]ETHYL}ACETAMIDE 3-[4-(AMINOSULFONYL)PHENYL]PROPANOIC ACID ETHYL 3-[4-(AMINOSULFONYL)PHENYL]PROPANOATE Ellagic acid Sodium carbonate Sodium sulfate
Diseases
GWAS		Blood protein levels ( 30072576) Blood trace element (Zn levels) ( 23720494) High light scatter reticulocyte count ( 27863252 32888494) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Reticulocyte count ( 27863252 32888494) Reticulocyte fraction of red cells ( 27863252 32888494) Zinc levels ( 26025379)
Interacting Genes		3 interacting genes: HSD17B7 MAPK6 TFCP2
Entrez ID		759
HPRD ID		00265
Ensembl ID		ENSG00000133742
Uniprot IDs		P00915 V9HWE3
PDB IDs		1AZM 1BZM 1CRM 1CZM 1HCB 1HUG 1HUH 1J9W 1JV0 2CAB 2FOY 2FW4 2IT4 2NMX 2NN1 2NN7 3LXE 3W6H 3W6I 4WR7 4WUP 4WUQ 5E2M 5GMM 6EVR 6EX1 6F3B 6FAF 6FAG 6G3V 6HWZ 6I0J 6I0L 6SWM 6XZE 6XZO 6XZS 6XZX 6XZY 6Y00 7PLF 7Q0D 7QOB 7ZL5 8CDX 8CDZ 8Q6L 8Q7G 8QGV 8QQ9 8QUN 8RLO 8S4F
Enriched GO Terms of Interacting Partners?		Septin Cytoskeleton 3-beta-hydroxysteroid 3-dehydrogenase (NADP+) Activity 5-alpha-androstane-3-beta,17-beta-diol Dehydrogenase (NADP+) Activity
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