CA1 and HSD17B7

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		CA1	HSD17B7
Gene Name		carbonic anhydrase I	hydroxysteroid (17-beta) dehydrogenase 7
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Extracellular Vesicular Exosome	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane
	Molecular Function	Carbonate Dehydratase Activity Zinc Ion Binding	3-keto Sterol Reductase Activity Estradiol 17-beta-dehydrogenase Activity Prolactin Receptor Binding
	Biological Process	One-carbon Metabolic Process Bicarbonate Transport Small Molecule Metabolic Process	Cholesterol Biosynthetic Process Estrogen Biosynthetic Process Small Molecule Metabolic Process Oxidation-reduction Process
Pathways		O2/CO2 exchange in erythrocytes Erythrocytes take up carbon dioxide and release oxygen Erythrocytes take up oxygen and release carbon dioxide Reversible hydration of carbon dioxide	Cholesterol biosynthesis Metabolism of lipids and lipoproteins
Drugs		Methyclothiazide Ethoxzolamide Amlodipine Methocarbamol Bendroflumethiazide Benzthiazide Cyclothiazide Methazolamide Hydroflumethiazide Acetazolamide Dorzolamide Chlorothiazide Zonisamide Hydrochlorothiazide Trichlormethiazide Ethinamate Diazoxide Dichlorphenamide Brinzolamide Quinethazone N-{2-[4-(AMINOSULFONYL)PHENYL]ETHYL}ACETAMIDE 3-[4-(AMINOSULFONYL)PHENYL]PROPANOIC ACID ETHYL 3-[4-(AMINOSULFONYL)PHENYL]PROPANOATE Ellagic Acid	NADH
Diseases
GWAS		Blood trace element (Zn levels) ( 23720494)
Protein-Protein Interactions		3 interactors: HSD17B7 MAPK6 TFCP2	6 interactors: AGPAT6 BRSK1 CA1 DTYMK GORAB VKORC1
Entrez ID		759	51478
HPRD ID		00265	05996
Ensembl ID		ENSG00000133742	ENSG00000132196
Uniprot IDs		P00915	P56937
PDB IDs		1AZM 1BZM 1CRM 1CZM 1HCB 1HUG 1HUH 1J9W 1JV0 2CAB 2FOY 2FW4 2IT4 2NMX 2NN1 2NN7 3LXE 3W6H 3W6I
Enriched GO Terms of Interacting Partners?			Nucleoside Monophosphate Phosphorylation DTDP Biosynthetic Process Small Molecule Metabolic Process DUDP Biosynthetic Process Glandular Epithelial Cell Maturation Vitamin K Metabolic Process DTTP Biosynthetic Process Cofactor Metabolic Process Deoxyribonucleoside Diphosphate Metabolic Process Nucleoside Diphosphate Biosynthetic Process CDP-diacylglycerol Biosynthetic Process CDP-diacylglycerol Metabolic Process Peptidyl-glutamic Acid Carboxylation Deoxyribonucleotide Biosynthetic Process Diacylglycerol Metabolic Process Nucleobase-containing Small Molecule Interconversion Epithelial Cell Maturation Phosphatidylcholine Biosynthetic Process Phosphatidic Acid Biosynthetic Process Phosphatidic Acid Metabolic Process Deoxyribonucleoside Triphosphate Metabolic Process Regulation Of Body Fluid Levels Glandular Epithelial Cell Development Bicarbonate Transport Secretion Centrosome Duplication G2 DNA Damage Checkpoint One-carbon Metabolic Process Anatomical Structure Development Quinone Metabolic Process Drug Metabolic Process Triglyceride Biosynthetic Process Columnar/cuboidal Epithelial Cell Development Glandular Epithelial Cell Differentiation Myoblast Differentiation Deoxyribonucleotide Metabolic Process Phosphatidylcholine Metabolic Process Pyrimidine Nucleotide Biosynthetic Process Developmental Process Centrosome Cycle Lactation Nucleotide Phosphorylation Response To Cadmium Ion Nucleoside Diphosphate Metabolic Process Acyl-CoA Metabolic Process Cellular Metabolic Process Phosphate-containing Compound Metabolic Process Pyrimidine Nucleotide Metabolic Process Cellular Ketone Metabolic Process Organophosphate Metabolic Process
Tagcloud ?		accumbens amygdala caudate coeruleus dentate dependence frontal grey gyrus hippocampus hypothalamic infusion intracerebroventricular microl minipumps morphine mrnas nmda nmol nr1 nr2a nr2b nri nucleus opioid osmotic paraventricular putamen tolerance	1a akr1c3 androgenic androstenedione comt cyp19a1 cyp1b1 cyp3a5 e1s ers esr2 estrogens extents gper gstp1 hec hieec hsd3b2 hydroxyestrogens ishikawa metabolized nqo2 quinones sulfatase sult1a1 sult2b1 ugt2b7
Tagcloud (Difference) ?		accumbens amygdala caudate coeruleus dentate dependence frontal grey gyrus hippocampus hypothalamic infusion intracerebroventricular microl minipumps morphine mrnas nmda nmol nr1 nr2a nr2b nri nucleus opioid osmotic paraventricular putamen tolerance	1a akr1c3 androgenic androstenedione comt cyp19a1 cyp1b1 cyp3a5 e1s ers esr2 estrogens extents gper gstp1 hec hieec hsd3b2 hydroxyestrogens ishikawa metabolized nqo2 quinones sulfatase sult1a1 sult2b1 ugt2b7
Tagcloud (Intersection) ?