ZSCAN21 and CAVIN1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZSCAN21	CAVIN1
Description		zinc finger and SCAN domain containing 21	caveolae associated protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Cytoplasm Mitochondrion Endoplasmic Reticulum Cytosol Plasma Membrane Caveola Membrane Protein-containing Complex Membrane Raft
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	RNA Binding Protein Binding RRNA Binding RRNA Primary Transcript Binding Identical Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Male Meiosis I Spermatogenesis Cell Differentiation Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Meiotic Cell Cycle	DNA-templated Transcription Termination Transcription Initiation At RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription RRNA Transcription Protein Secretion Positive Regulation Of Cell Motility
Pathways			RNA Polymerase I Transcription Termination RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		25 interacting genes: APP BRCA1 CAVIN1 CEP70 CLK2 DVL3 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 OGT PICK1 SCAND1 TRIM41 ZKSCAN7 ZNF396 ZNF446 ZNF483 ZNF496 ZNF837 ZSCAN12 ZSCAN22	24 interacting genes: CDC37 CDCA7L DNTTIP2 DUX4 ERCC6 INO80B KAT5 MECOM MRPL45 NKX2-1 OGT SOCS3 SPANXN3 TNFAIP8L1 TSGA10IP TTC5 TTF1 UBC UBE2O YAF2 ZCCHC10 ZFP1 ZNF148 ZSCAN21
Entrez ID		7589	284119
HPRD ID		03162	04433
Ensembl ID		ENSG00000166529	ENSG00000177469
Uniprot IDs		G3V0F4 Q9Y5A6	Q6NZI2
PDB IDs			9EG6 9EGN 9EIU
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament Identical Protein Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Zinc Ion Binding Regulation Of RNA Metabolic Process DNA Binding	Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Nucleoplasm Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Nucleolus Regulation Of RNA Metabolic Process DNA Binding Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Circadian Rhythm Positive Regulation Of Biosynthetic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Histone Acetyltransferase Complex Regulation Of Primary Metabolic Process Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of DNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Chromatin Organization Positive Regulation Of DNA Repair Positive Regulation Of Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Histone H2AK5 Acetyltransferase Activity Negative Regulation Of Double-strand Break Repair Negative Regulation Of DNA Repair Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Chromatin Remodeling Regulation Of Macromolecule Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
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