ZSCAN21 and ZNF396

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZSCAN21	ZNF396
Description		zinc finger and SCAN domain containing 21	zinc finger protein 396
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromatin Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Protein Homodimerization Activity Sequence-specific DNA Binding Metal Ion Binding Protein Heterodimerization Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Male Meiosis I Spermatogenesis Cell Differentiation Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Meiotic Cell Cycle	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)	Parasitemia in Tripanosoma cruzi seropositivity ( 24324551) Parkinson's disease ( 26227905)
Interacting Genes		25 interacting genes: APP BRCA1 CAVIN1 CEP70 CLK2 DVL3 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 OGT PICK1 SCAND1 TRIM41 ZKSCAN7 ZNF396 ZNF446 ZNF483 ZNF496 ZNF837 ZSCAN12 ZSCAN22	8 interacting genes: CDKN2D NFE2L2 PROSER3 SPSB3 ZNF397 ZSCAN1 ZSCAN21 ZSCAN32
Entrez ID		7589	252884
HPRD ID		03162	18334
Ensembl ID		ENSG00000166529	ENSG00000186496
Uniprot IDs		G3V0F4 Q9Y5A6	Q96N95
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament Identical Protein Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Zinc Ion Binding Regulation Of RNA Metabolic Process DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
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