YWHAG and ALB

Number of citations of the paper that reports this interaction (PMID 15324660)
121

Data Source:
HPRD (in vivo)

		YWHAG	ALB
Gene Name		tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma	albumin
Image
Gene Ontology Annotations	Cellular Component	Cytosol Focal Adhesion Membrane Cytoplasmic Vesicle Membrane Extracellular Vesicular Exosome	Extracellular Region Basement Membrane Extracellular Space Nucleus Platelet Alpha Granule Lumen Protein Complex Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Protein Kinase C Binding Insulin-like Growth Factor Receptor Binding Protein Binding Protein Kinase C Inhibitor Activity Protein Domain Specific Binding Receptor Tyrosine Kinase Binding Poly(A) RNA Binding	DNA Binding Fatty Acid Binding Copper Ion Binding Protein Binding Drug Binding Zinc Ion Binding Toxic Substance Binding Antioxidant Activity Oxygen Binding Enzyme Binding Pyridoxal Phosphate Binding Chaperone Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Negative Regulation Of Protein Kinase Activity Protein Targeting Apoptotic Process Organelle Organization Regulation Of Signal Transduction Cellular Response To Insulin Stimulus Regulation Of Neuron Differentiation Regulation Of Synaptic Plasticity Membrane Organization Negative Regulation Of Protein Serine/threonine Kinase Activity Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway	Retina Homeostasis Platelet Degranulation Transport Receptor-mediated Endocytosis Response To Nutrient Blood Coagulation Bile Acid Metabolic Process Cellular Response To Starvation Response To Organic Substance Bile Acid And Bile Salt Transport Hemolysis By Symbiont Of Host Erythrocytes Platelet Activation Lipoprotein Metabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Sodium-independent Organic Anion Transport Small Molecule Metabolic Process Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Response To Mercury Ion Maintenance Of Mitochondrion Location Transmembrane Transport Response To Platinum Ion
Pathways		Organelle biogenesis and maintenance Translocation of GLUT4 to the plasma membrane Activation of BH3-only proteins Assembly of the primary cilium G2/M Transition Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane Cell Cycle, Mitotic Activation of BAD and translocation to mitochondria Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes Programmed Cell Death Centrosome maturation Mitotic G2-G2/M phases Recruitment of mitotic centrosome proteins and complexes Intrinsic Pathway for Apoptosis	Lipoprotein metabolism Bile acid and bile salt metabolism Metabolism of lipids and lipoproteins Recycling of bile acids and salts Platelet degranulation Lipid digestion, mobilization, and transport Transport of organic anions SLC-mediated transmembrane transport HDL-mediated lipid transport Scavenging of heme from plasma Response to elevated platelet cytosolic Ca2+ Platelet activation, signaling and aggregation Transport of vitamins, nucleosides, and related molecules
Drugs
Diseases
GWAS		Multiple sclerosis ( 21654844)	Lipid metabolism phenotypes ( 22286219) Prostate cancer ( 23535732)
Protein-Protein Interactions		285 interactors: ABL1 ABLIM1 ACIN1 AKAP13 AKT1S1 ALB ANKHD1-EIF4EBP3 ANKS1A APP ARAF ARHGEF2 ARHGEF6 ARHGEF7 ATP5A1 ATP5B ATP6V0B BAD BAIAP2 BAIAP2L1 BCLAF1 BCR BRAF C1QBP CAD CAMKK1 CASP3 CBL CCNY CCS CCT2 CDC5L CDK11B CDK16 CDK17 CDKN1B CENPJ CEP170 CEP250 CEP95 CFAP20 CFL1 CGN CGNL1 CHAF1A CHEK1 CKAP2 CLASP1 CLINT1 CLK1 CLK2 CLK3 CLTC COPS5 CPSF3 CRTC1 CRTC2 CRTC3 CSE1L CTNND1 CTPS1 CYFIP2 DCAF7 DCP1A DDX17 DDX27 DDX39B DENND4A DFFA DHX15 DISC1 DOCK7 DYNC1H1 DYRK1A EDC3 EEF1A1 EEF1G EML3 EPB41L2 EPB41L3 EPN2 ERC1 EWSR1 EXO1 FAM13B FAM53C FAM65B FARP2 FGD6 FLNA FOXO1 FOXO3 GBF1 GIT1 GIT2 GSK3A GTPBP4 HDAC4 HDAC7 HECTD1 HIST1H3A HIVEP2 HNRNPAB HNRNPH1 HNRNPM HOXC10 HSPA1A HSPA8 HSPA9 HSPB6 HSPD1 IGF1R IL7R ING1 INPP5E IRS1 IRS2 IRS4 JAKMIP1 KAT5 KCNK15 KCNK3 KCNK9 KIAA0408 KIAA0930 KIF1B KIF1C KIF23 KIF5B KIF5C KLC2 KLC3 KRT18 LARP1 LATS2 LBR LIMA1 LMO7 LRCH3 LSR LTB4R LUC7L2 LUC7L3 MAGOHB MAP3K2 MAP3K3 MAPKAP1 MARK3 MCM5 MDM4 MFAP1 MICALL1 MIEF1 MLLT4 MPHOSPH9 MPRIP MSL2 MYCBP2 MYH10 N4BP3 NCKAP1 NCKIPSD NDE1 NDEL1 NEDD4L NEFL NOLC1 NUFIP2 NUMBL OSBPL3 P4HB PABPC1 PAK1 PAK4 PARD3 PARD3B PFKFB2 PGAM5 PHLDB2 PI4KB PIK3C3 PIK3R1 PKP2 PLA2G12A PLEKHA5 PNN POT1 PPFIA1 PPFIBP1 PPIG PPP1R12A PPP6R3 PRKCA PRKCB PRKCD PRKCG PRKCQ PRKDC PRLR PRMT1 PRMT5 PRPF38B PRPF40A PRPF4B PTPN14 PTPN3 PUF60 RAB11A RAB11FIP2 RAB11FIP5 RABEP1 RACGAP1 RAF1 RAI14 RALGPS2 RAPGEF6 RASAL2 RASSF8 RGS12 RMDN3 RNPS1 RPS2 RRM1 SAMD4A SAMD4B SF3B3 SFN SH3BP4 SH3BP5L SHKBP1 SHPRH SHROOM2 SIMC1 SLC25A3 SMARCD1 SNRNP200 SON SPTBN1 SRC SRGAP2 SRPK1 SRRM1 SRRM2 SRSF10 SRSF3 SSFA2 SVIL SYNPO SYNPO2 TAB1 TAF15 TBC1D1 TBC1D4 TERF1 TFE3 THRAP3 TIAM1 TINF2 TJP2 TMEM102 TNFAIP3 TP53 TP53BP2 TRA2A TRA2B TSC1 TSC2 TUBA4A TUBB TUBB4A UBC UCP2 UCP3 USP37 USP8 WEE1 WNK1 WWTR1 YAP1 YWHAB YWHAE YWHAH YWHAQ ZAK ZBTB21 ZFP36	24 interactors: AGA AMBP APOE APP CRYAA CUBN F7 FCGRT HNF1A IMMT KLK3 LRP2 LUC7L2 NR5A2 ORM1 PFDN1 PON1 PRB3 RBP4 RYR2 SRGN ST13 TK1 YWHAG
Entrez ID		7532	213
HPRD ID		05639	00062
Ensembl ID		ENSG00000170027	ENSG00000163631
Uniprot IDs		P61981	C9JKR2 P02768
PDB IDs		2B05 3UZD 4E2E 4J6S	1AO6 1BJ5 1BKE 1BM0 1E78 1E7A 1E7B 1E7C 1E7E 1E7F 1E7G 1E7H 1E7I 1GNI 1GNJ 1H9Z 1HA2 1HK1 1HK2 1HK3 1HK4 1HK5 1N5U 1O9X 1TF0 1UOR 1YSX 2BX8 2BXA 2BXB 2BXC 2BXD 2BXE 2BXF 2BXG 2BXH 2BXI 2BXK 2BXL 2BXM 2BXN 2BXO 2BXP 2BXQ 2ESG 2I2Z 2I30 2VDB 2VUE 2VUF 2XSI 2XVQ 2XVU 2XVV 2XVW 2XW0 2XW1 2YDF 3A73 3B9L 3B9M 3CX9 3JQZ 3JRY 3LU6 3LU7 3LU8 3SQJ 3TDL 3UIV 4E99 4EMX 4G03 4G04 4HGK 4HGM 4IW1 4IW2 4K2C 4L8U 4L9K 4L9Q 4LA0 4LB2 4LB9
Enriched GO Terms of Interacting Partners?		Intracellular Signal Transduction Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Metabolic Process Regulation Of Cellular Component Organization Cell Death Apoptotic Process Programmed Cell Death Death Cellular Component Assembly RNA Splicing Organelle Organization Neurotrophin TRK Receptor Signaling Pathway Regulation Of Metabolic Process MRNA Metabolic Process MRNA Processing Neurotrophin Signaling Pathway Cell Cycle Regulation Of Signaling Cellular Process Regulation Of Cellular Process Cellular Response To Growth Factor Stimulus Mitotic Cell Cycle Cellular Localization RNA Processing Mitotic Cell Cycle Process Regulation Of Signal Transduction Response To Growth Factor Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Apoptotic Process Fc Receptor Signaling Pathway Regulation Of Catalytic Activity Positive Regulation Of Catalytic Activity Regulation Of Cell Death Response To Organic Substance Cell Cycle Process Cellular Response To Organic Substance Establishment Of Localization In Cell System Development Regulation Of Cell Cycle Fibroblast Growth Factor Receptor Signaling Pathway Developmental Process MRNA Splicing, Via Spliceosome Regulation Of Organelle Organization Cell Communication RNA Splicing, Via Transesterification Reactions Cellular Response To Stimulus Signaling Response To Stimulus	Alcohol Metabolic Process Steroid Metabolic Process Cholesterol Metabolic Process Sterol Metabolic Process Chemical Homeostasis Lipid Metabolic Process Homeostatic Process Response To External Stimulus Response To Stimulus Phototransduction, Visible Light Retinoid Metabolic Process Tetrapyrrole Metabolic Process Vitamin D Metabolic Process Diterpenoid Metabolic Process Detection Of Visible Light Phototransduction Regulation Of Blood Coagulation Response To Lipid Positive Regulation Of Cholesterol Efflux Reverse Cholesterol Transport Detection Of Light Stimulus Positive Regulation Of Cholesterol Transport Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis System Development Isoprenoid Metabolic Process Small Molecule Metabolic Process Regulation Of Cholesterol Efflux Response To Hormone Regulation Of Wound Healing Organ Development Response To Light Stimulus Vesicle-mediated Transport Receptor-mediated Endocytosis Endocytosis Regulation Of Cellular Localization Response To Organic Substance Response To Wounding Response To Abiotic Stimulus Cellular Metal Ion Homeostasis Positive Regulation Of Transport Bile Acid Metabolic Process Detection Of Abiotic Stimulus Regulation Of Cholesterol Transport Blood Coagulation Tissue Homeostasis Hemostasis Response To Nutrient Levels Heme Metabolic Process Multicellular Organismal Development
Tagcloud ?		7q11 atypical autism autistic baz1b beuren carry centromeric deletions epilepsy excludes flanking fzd9 haploinsufficiency hemizygous hip1 huntingtin mb monooxigenase monooxygenase multisystemic neuropsychological preservation shed spanning svas tryptophan wbs williams	ambulatory anabolic anthropometric calls capd catabolism causal complicating declined deterioration dialysis haemodialysis instead malnutrition mmol nutrineal nutrition osmotic peritoneal phosphates phosphorus rule solution substituted termination transferrin uraemic urea wilcoxon
Tagcloud (Difference) ?		7q11 atypical autism autistic baz1b beuren carry centromeric deletions epilepsy excludes flanking fzd9 haploinsufficiency hemizygous hip1 huntingtin mb monooxigenase monooxygenase multisystemic neuropsychological preservation shed spanning svas tryptophan wbs williams	ambulatory anabolic anthropometric calls capd catabolism causal complicating declined deterioration dialysis haemodialysis instead malnutrition mmol nutrineal nutrition osmotic peritoneal phosphates phosphorus rule solution substituted termination transferrin uraemic urea wilcoxon
Tagcloud (Intersection) ?