UFD1L and UBXN6

Number of citations of the paper that reports this interaction (PMID 19275885)
3

Data Source:
BioGRID (pull down)

		UFD1L	UBXN6
Gene Name		ubiquitin fusion degradation 1 like (yeast)	UBX domain protein 6
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol	Nucleus Nucleolus Cytoplasm Microtubule Organizing Center Extracellular Vesicular Exosome
	Molecular Function	Ubiquitin-specific Protease Activity Receptor Binding Protein Binding Protein Complex Binding	Molecular_function Protein Binding
	Biological Process	Skeletal System Development Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Biological_process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: A2M AMFR ANAPC2 F13A1 GZMK IGHM MASP1 NEDD8 NGFR NPLOC4 NUB1 PIK3CA PPHLN1 SNX1 TAF1C TIAM2 TP53 UBXN6 VCP	7 interactors: APP DERL1 GSK3B MAGEA4 TRIM39 UFD1L VCP
Entrez ID		7353	80700
HPRD ID		06778	18253
Ensembl ID		ENSG00000070010	ENSG00000167671
Uniprot IDs		Q541A5 Q92890	Q9BZV1
PDB IDs		2YUJ
Enriched GO Terms of Interacting Partners?		Proteolysis Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process ER-associated Ubiquitin-dependent Protein Catabolic Process Protein Catabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Protein Catabolic Process Cellular Macromolecule Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Response To Growth Factor Stimulus Negative Regulation Of Complement Activation ER-nucleus Signaling Pathway Response To Growth Factor Regulation Of Fibroblast Apoptotic Process Protein Modification By Small Protein Conjugation Regulation Of Proteolysis Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Protein Catabolic Process Protein Metabolic Process Positive Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Response To Endoplasmic Reticulum Stress Blood Coagulation Hemostasis Regulation Of Complement Activation Cellular Response To Organic Substance Response To Organic Substance Platelet Activation Regulation Of Proteasomal Protein Catabolic Process Enzyme Linked Receptor Protein Signaling Pathway Response To Stress Neurotrophin TRK Receptor Signaling Pathway Vesicle-mediated Transport Neurotrophin Signaling Pathway Regulation Of Humoral Immune Response Positive Regulation Of Lys63-specific Deubiquitinase Activity Positive Regulation Of Protein K63-linked Deubiquitination Regulation Of Body Fluid Levels Protein Ubiquitination Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Wound Healing Positive Regulation Of Cell Death Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process	Retrograde Protein Transport, ER To Cytosol ER-nucleus Signaling Pathway Response To Endoplasmic Reticulum Stress Regulation Of Proteolysis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process ER-associated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Apoptotic Process Programmed Cell Death Cell Death Death Regulation Of Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Response To Heat Positive Regulation Of Proteasomal Protein Catabolic Process Cellular Protein Metabolic Process Positive Regulation Of Lys63-specific Deubiquitinase Activity Positive Regulation Of Protein K63-linked Deubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Unfolded Protein Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Cellular Response To Topologically Incorrect Protein Response To Heat Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Intracellular Transport Protein Catabolic Process Positive Regulation Of Cell Death Negative Regulation Of Type B Pancreatic Cell Development Synaptic Growth At Neuromuscular Junction Superior Temporal Gyrus Development Response To Unfolded Protein Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Peptidase Activity Regulation Of Protein Binding Positive Regulation Of Cellular Protein Catabolic Process Re-entry Into Mitotic Cell Cycle Collateral Sprouting In Absence Of Injury Negative Regulation Of Neuron Maturation Protein Metabolic Process Positive Regulation Of Protein Complex Assembly Hypermethylation Of CpG Island Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Negative Regulation Of Cellular Protein Metabolic Process Response To Temperature Stimulus
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