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UBE3A and C11orf49
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
UBE3A
C11orf49
Gene Name
ubiquitin protein ligase E3A
chromosome 11 open reading frame 49
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Proteasome Complex
Nucleus
Cytoplasm
Cytosol
Nucleoplasm
Molecular Function
Transcription Coactivator Activity
Ubiquitin-protein Transferase Activity
Protein Binding
Ligase Activity
Biological Process
Ovarian Follicle Development
Proteolysis
Ubiquitin-dependent Protein Catabolic Process
Brain Development
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Viral Process
Androgen Receptor Signaling Pathway
Sperm Entry
Regulation Of Circadian Rhythm
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Protein Autoubiquitination
Prostate Gland Growth
Protein K48-linked Ubiquitination
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Drugs
Diseases
GWAS
Cardiac hypertrophy (
21348951
)
Obesity-related traits (
23251661
)
D-dimer levels (
21502573
)
Protein-Protein Interactions
80 interactors:
ADRM1
AFG3L1P
AFTPH
AHSP
ANXA1
APP
AR
ARC
ASAP3
ATG9A
BARD1
BLK
BPY2
BPY2B
BPY2C
BRCA1
C11orf49
CDKN1B
CEBPZ
DLG1
EAPP
EID1
EIF4G1
HBA1
HPCAL4
HSPA4
JADE1
KLHL38
LCK
MAGEA8
MCM7
MDM2
MEOX2
NDUFA13
NELFCD
NOMO2
PARVA
PDE1B
PGR
PML
POLE4
PRDX1
PSAP
PSMC3
PSMD4
RAD23A
RAD23B
RARA
RMI1
RNF2
SACS
SCAMP1
SCRIB
SGK223
SHBG
SMAD9
SOD1
SUMO3
TAT
TBC1D14
TCF19
TP53
TRIM65
TSC2
TTC3
UBB
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2G1
UBE2G2
UBE2L3
UBE2L6
UBQLN2
UCHL5
YOD1
YWHAE
YWHAZ
12 interactors:
ARHGEF15
CDC16
GSR
PNMA5
PSMA1
RAB17
RAB29
RBM48
RPL8
RPS3A
UBE3A
UBQLN4
Entrez ID
7337
79096
HPRD ID
03375
08332
Ensembl ID
ENSG00000114062
ENSG00000149179
Uniprot IDs
Q05086
Q9BUI6
Q9H2G0
B4DUV7
Q9H6J7
PDB IDs
1C4Z
1D5F
1EQX
2KR1
4GIZ
Enriched GO Terms of Interacting Partners
?
Protein Polyubiquitination
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Regulation Of Proteolysis
Positive Regulation Of Proteolysis
Protein Catabolic Process
Response To Stress
Cellular Response To Organic Substance
Regulation Of Mitotic Cell Cycle Phase Transition
Protein Modification By Small Protein Conjugation
Negative Regulation Of Mitotic Cell Cycle
Regulation Of Cellular Protein Metabolic Process
Regulation Of Cell Cycle Phase Transition
Negative Regulation Of Cell Cycle
Regulation Of Protein Metabolic Process
Response To Organic Substance
Cellular Macromolecule Catabolic Process
Positive Regulation Of Cellular Metabolic Process
Protein Ubiquitination
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Protein Catabolic Process
Positive Regulation Of Cell Cycle Arrest
Positive Regulation Of Metabolic Process
Regulation Of Mitotic Cell Cycle
DNA Damage Response, Signal Transduction By P53 Class Mediator
Mitotic Cell Cycle Checkpoint
Cell Death
Death
Cell Cycle Checkpoint
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Apoptotic Process
Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Signal Transduction Involved In DNA Damage Checkpoint
Regulation Of Cell Cycle G1/S Phase Transition
Signal Transduction In Response To DNA Damage
Signal Transduction Involved In Cell Cycle Checkpoint
Regulation Of Cell Cycle Arrest
Programmed Cell Death
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Regulation Of Catalytic Activity
Proteasomal Protein Catabolic Process
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Protein K48-linked Ubiquitination
Regulation Of Cell Cycle
Catabolic Process
Mitotic G1 DNA Damage Checkpoint
Mitotic G1/S Transition Checkpoint
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Regulation Of Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Protein Polyubiquitination
Viral Process
Regulation Of Protein Ubiquitination
Regulation Of Proteolysis
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Rab Protein Signal Transduction
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Cellular Pigmentation
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Negative Regulation Of Ubiquitin-protein Transferase Activity
Sperm Entry
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Regulation Of Synapse Organization
Regulation Of Ubiquitin-protein Transferase Activity
Catabolic Process
Viral Transcription
Regulation Of Synapse Structure Or Activity
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
SRP-dependent Cotranslational Protein Targeting To Membrane
Negative Regulation Of Synapse Maturation
Immunoglobulin Transcytosis In Epithelial Cells Mediated By Polymeric Immunoglobulin Receptor
Cotranslational Protein Targeting To Membrane
Protein Targeting To ER
Negative Regulation Of Protein Ubiquitination
Establishment Of Protein Localization To Endoplasmic Reticulum
Pigmentation
Ubiquitin-dependent Protein Catabolic Process
Retrograde Transport, Plasma Membrane To Golgi
Modification-dependent Protein Catabolic Process
Protein Localization To Endoplasmic Reticulum
Positive Regulation Of Protein Ubiquitination
Proteolysis Involved In Cellular Protein Catabolic Process
Immunoglobulin Transcytosis In Epithelial Cells
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cellular Protein Catabolic Process
Translational Termination
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Protein Ubiquitination
Nuclear-transcribed MRNA Catabolic Process
Positive Regulation Of Cellular Protein Catabolic Process
MRNA Catabolic Process
Protein Modification By Small Protein Conjugation
Protein Catabolic Process
Tagcloud
?
2h5
accompanies
anova
dynactin
gadd45a
gtf2h5
invites
keuls
macaques
malfunctioning
nbn1
ndd
ndds
newman
ovx
perimenopausal
presenilin1
proteosome
psen1
rad23a
raphe
scna
serotonin
speculation
subserving
symptomology
ube2d3
ubea5
ubiquinase
Tagcloud (Difference)
?
2h5
accompanies
anova
dynactin
gadd45a
gtf2h5
invites
keuls
macaques
malfunctioning
nbn1
ndd
ndds
newman
ovx
perimenopausal
presenilin1
proteosome
psen1
rad23a
raphe
scna
serotonin
speculation
subserving
symptomology
ube2d3
ubea5
ubiquinase
Tagcloud (Intersection)
?