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C11orf49 and ARHGEF15
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
HPRD
(two hybrid)
C11orf49
ARHGEF15
Gene Name
chromosome 11 open reading frame 49
Rho guanine nucleotide exchange factor (GEF) 15
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Dendrite
Molecular Function
Rho Guanyl-nucleotide Exchange Factor Activity
GTPase Activator Activity
Protein Binding
Biological Process
Positive Regulation Of Rho GTPase Activity
Regulation Of Catalytic Activity
Positive Regulation Of Stress Fiber Assembly
Retina Vasculature Morphogenesis In Camera-type Eye
Negative Regulation Of Synapse Maturation
Pathways
Drugs
Diseases
GWAS
D-dimer levels (
21502573
)
Protein-Protein Interactions
12 interactors:
ARHGEF15
CDC16
GSR
PNMA5
PSMA1
RAB17
RAB29
RBM48
RPL8
RPS3A
UBE3A
UBQLN4
8 interactors:
C11orf49
CEP55
EPHA4
ESR1
ESRRG
LASP1
MOB4
PIN1
Entrez ID
79096
22899
HPRD ID
08332
10535
Ensembl ID
ENSG00000149179
ENSG00000198844
Uniprot IDs
B4DUV7
Q9H6J7
O94989
PDB IDs
Enriched GO Terms of Interacting Partners
?
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Regulation Of Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Protein Polyubiquitination
Viral Process
Regulation Of Protein Ubiquitination
Regulation Of Proteolysis
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Rab Protein Signal Transduction
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Cellular Pigmentation
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Negative Regulation Of Ubiquitin-protein Transferase Activity
Sperm Entry
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Regulation Of Synapse Organization
Regulation Of Ubiquitin-protein Transferase Activity
Catabolic Process
Viral Transcription
Regulation Of Synapse Structure Or Activity
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
SRP-dependent Cotranslational Protein Targeting To Membrane
Negative Regulation Of Synapse Maturation
Immunoglobulin Transcytosis In Epithelial Cells Mediated By Polymeric Immunoglobulin Receptor
Cotranslational Protein Targeting To Membrane
Protein Targeting To ER
Negative Regulation Of Protein Ubiquitination
Establishment Of Protein Localization To Endoplasmic Reticulum
Pigmentation
Ubiquitin-dependent Protein Catabolic Process
Retrograde Transport, Plasma Membrane To Golgi
Modification-dependent Protein Catabolic Process
Protein Localization To Endoplasmic Reticulum
Positive Regulation Of Protein Ubiquitination
Proteolysis Involved In Cellular Protein Catabolic Process
Immunoglobulin Transcytosis In Epithelial Cells
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cellular Protein Catabolic Process
Translational Termination
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Protein Ubiquitination
Nuclear-transcribed MRNA Catabolic Process
Positive Regulation Of Cellular Protein Catabolic Process
MRNA Catabolic Process
Protein Modification By Small Protein Conjugation
Protein Catabolic Process
Positive Regulation Of Rho Guanyl-nucleotide Exchange Factor Activity
Steroid Hormone Mediated Signaling Pathway
Fasciculation Of Motor Neuron Axon
Hormone-mediated Signaling Pathway
Fasciculation Of Sensory Neuron Axon
Prostate Epithelial Cord Elongation
Transcription Initiation From RNA Polymerase II Promoter
Cellular Response To Steroid Hormone Stimulus
Negative Regulation Of Axon Regeneration
Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation
Positive Regulation Of Retinoic Acid Receptor Signaling Pathway
Intracellular Receptor Signaling Pathway
Branch Elongation Involved In Mammary Gland Duct Branching
Antral Ovarian Follicle Growth
DNA-templated Transcription, Initiation
Regulation Of Branching Involved In Prostate Gland Morphogenesis
Mammary Gland Branching Involved In Pregnancy
Regulation Of Rho GTPase Activity
Prostate Epithelial Cord Arborization Involved In Prostate Glandular Acinus Morphogenesis
Positive Regulation Of Cellular Metabolic Process
Regulation Of Rho Protein Signal Transduction
Corticospinal Tract Morphogenesis
Vagina Development
Positive Regulation Of Signal Transduction
Regulation Of Axon Regeneration
Uterus Development
Regulation Of Signal Transduction
Cellular Response To Organic Cyclic Compound
Intracellular Estrogen Receptor Signaling Pathway
Positive Regulation Of Nitric-oxide Synthase Activity
Cell Separation After Cytokinesis
Regulation Of Rap GTPase Activity
Cellular Response To Estradiol Stimulus
Prostate Gland Growth
Regulation Of Rac GTPase Activity
Branching Involved In Prostate Gland Morphogenesis
Negative Regulation Of Intracellular Signal Transduction
Cellular Response To Lipid
Mammary Gland Epithelial Cell Proliferation
Female Genitalia Development
Axonal Fasciculation
Regulation Of Rap Protein Signal Transduction
Regulation Of Signaling
Positive Regulation Of Monooxygenase Activity
Branch Elongation Of An Epithelium
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