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TXNRD1 and TXNDC17
Number of citations of the paper that reports this interaction (PMID
14607844
)
12
Data Source:
HPRD
(in vitro)
TXNRD1
TXNDC17
Gene Name
thioredoxin reductase 1
thioredoxin domain containing 17
Image
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Nucleolus
Cytosol
Extracellular Vesicular Exosome
Cytosol
Extracellular Vesicular Exosome
Molecular Function
Thioredoxin-disulfide Reductase Activity
Protein Binding
Electron Carrier Activity
Protein Disulfide Oxidoreductase Activity
Flavin Adenine Dinucleotide Binding
Peroxidase Activity
Protein Binding
Electron Carrier Activity
Protein-disulfide Reductase Activity
Biological Process
Response To Reactive Oxygen Species
Signal Transduction
Nucleobase-containing Small Molecule Interconversion
Cellular Lipid Metabolic Process
Small Molecule Metabolic Process
Cell Redox Homeostasis
Nucleobase-containing Small Molecule Metabolic Process
Oxidation-reduction Process
Tumor Necrosis Factor-mediated Signaling Pathway
Oxidation-reduction Process
Pathways
PPARA activates gene expression
Fatty acid, triacylglycerol, and ketone body metabolism
Uptake and actions of bacterial toxins
Metabolism of lipids and lipoproteins
Detoxification of Reactive Oxygen Species
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Metabolism of nucleotides
Synthesis and interconversion of nucleotide di- and triphosphates
Uptake and function of diphtheria toxin
Drugs
Arsenic trioxide
Nadph Dihydro-Nicotinamide-Adenine-Dinucleotidephosphate
Flavin-Adenine Dinucleotide
Spermidine
Fotemustine
Diseases
GWAS
Protein-Protein Interactions
8 interactors:
DMRTC2
FOXO1
GLRX2
POU2F1
POU2F2
PPP1R16A
TXNDC17
TXNIP
8 interactors:
AVP
DYNLL1
EXOSC8
INS
OXT
RUFY1
TINF2
TXNRD1
Entrez ID
7296
84817
HPRD ID
03068
11656
Ensembl ID
ENSG00000198431
ENSG00000129235
Uniprot IDs
B7Z1F4
B7Z2S5
B7Z904
E7EW10
Q16881
Q9BRA2
PDB IDs
1W1C
2CFY
2J3N
2ZZ0
2ZZB
2ZZC
3QFA
3QFB
1WOU
Enriched GO Terms of Interacting Partners
?
Response To Reactive Oxygen Species
Cell Differentiation
Transcription, DNA-templated
RNA Biosynthetic Process
Response To Oxidative Stress
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Response To Inorganic Substance
Regulation Of RNA Metabolic Process
Cellular Response To Tumor Cell
Positive Regulation Of Histone H3-K9 Dimethylation
Positive Regulation Of Histone H3-K9 Trimethylation
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Immunoglobulin Secretion Involved In Immune Response
DNA Protection
Response To Hydrogen Peroxide
RNA Metabolic Process
Developmental Process
Nitrogen Compound Metabolic Process
Gene Expression
Cellular Macromolecule Biosynthetic Process
Response To Temperature Stimulus
Macromolecule Biosynthetic Process
Transcription From RNA Polymerase II Promoter
Cellular Response To Extracellular Stimulus
Response To Tumor Cell
Immunoglobulin Secretion
Olfactory Placode Formation
Cellular Response To Cold
Spermatid Nucleus Elongation
Regulation Of Gluconeogenesis By Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Response To Hyperoxia
Response To Abiotic Stimulus
Negative Regulation Of Transcription, DNA-templated
Lens Induction In Camera-type Eye
Positive Regulation Of Histone H3-K9 Methylation
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Response To Organic Substance
Regulation Of Energy Homeostasis
Positive Regulation Of Cellular Metabolic Process
Cellular Response To Nitric Oxide
Response To Redox State
Response To Nitric Oxide
Maternal Aggressive Behavior
Hyperosmotic Salinity Response
Aggressive Behavior
Regulation Of Cellular Component Organization
Regulation Of Female Receptivity
Maternal Behavior
Female Mating Behavior
Grooming Behavior
Regulation Of Renal Sodium Excretion
Copulation
Hyperosmotic Response
Regulation Of Excretion
Homeostatic Process
Mating Behavior
Positive Regulation Of Transport
Response To Salt Stress
Positive Regulation Of Blood Pressure
Social Behavior
Positive Regulation Of Secretion
Mating
Regulation Of Organelle Organization
Regulation Of Neurological System Process
Positive Regulation Of Lipid Biosynthetic Process
Regulation Of Cellular Localization
Positive Regulation Of Organelle Organization
Negative Regulation Of Protein ADP-ribosylation
Positive Regulation Of Hindgut Contraction
Regulation Of Fatty Acid Metabolic Process
Response To Osmotic Stress
Regulation Of Mitochondrion Organization
Renal System Process
Regulation Of Protein ADP-ribosylation
Negative Regulation Of Glycogen Catabolic Process
Regulation Of Hindgut Contraction
Ion Homeostasis
Positive Regulation Of Cell Growth
Regulation Of DNA Replication
Regulation Of Lipid Biosynthetic Process
Regulation Of Anion Transport
Negative Regulation Of Respiratory Burst Involved In Inflammatory Response
Negative Regulation Of NAD(P)H Oxidase Activity
Regulation Of Secretion
Positive Regulation Of DNA Metabolic Process
Response To Alkaloid
Regulation Of Carbohydrate Metabolic Process
Positive Regulation Of Cytosolic Calcium Ion Concentration
Cellular Homeostasis
Regulation Of Ion Homeostasis
Positive Regulation Of Cellular PH Reduction
Positive Regulation Of Norepinephrine Secretion
Tagcloud
?
bring
btg1
cyr61
dcs
e7
epha1
hla
idc
idcs
igfbp3
igsf6
il8
kpna7
mdc
mdcs
mrps11
ncr3
nfkb1a
nfkbia
padre
pgf
pidc
pulsed
pulsing
rad21
sema6a
srgn
trem2
tubal3
Tagcloud (Difference)
?
bring
btg1
cyr61
dcs
e7
epha1
hla
idc
idcs
igfbp3
igsf6
il8
kpna7
mdc
mdcs
mrps11
ncr3
nfkb1a
nfkbia
padre
pgf
pidc
pulsed
pulsing
rad21
sema6a
srgn
trem2
tubal3
Tagcloud (Intersection)
?