CDK11A and SKIV2L

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
BioGRID (two hybrid)

		CDK11A	SKIV2L
Gene Name		cyclin-dependent kinase 11A	superkiller viralicidic activity 2-like (S. cerevisiae)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleus Nucleoplasm Ski Complex
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity ATP Binding	RNA Binding ATP-dependent RNA Helicase Activity ATP Binding
	Biological Process	Regulation Of Cell Growth Regulation Of Transcription, DNA-templated Protein Phosphorylation Apoptotic Process Mitotic Nuclear Division Regulation Of MRNA Processing Regulation Of Cell Cycle	Metabolic Process
Pathways		G2/M Transition Centrosome maturation Mitotic G2-G2/M phases Cell Cycle, Mitotic Recruitment of mitotic centrosome proteins and complexes	Protein folding Chaperonin-mediated protein folding Association of TriC/CCT with target proteins during biosynthesis
Drugs
Diseases
GWAS			Age-related macular degeneration ( 23577725 20861866) Prostate cancer ( 23535732)
Protein-Protein Interactions		6 interactors: B4GALT1 CCNL1 EIF3F GADD45A PIN1 SKIV2L	11 interactors: CDK11A CDKL5 EXOSC10 EXOSC4 GALNT13 PMPCA SNRPB TNRC17 TSSK2 WDR1 XRN1
Entrez ID		728642	6499
HPRD ID			02724
Ensembl ID		ENSG00000008128	ENSG00000204351
Uniprot IDs		Q4VBY6 Q5QPR3 Q9UQ88	Q15477
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Cellular Protein Metabolic Process Lactose Biosynthetic Process Regulation Of Protein Metabolic Process Regulation Of Cell Cycle Disaccharide Metabolic Process Regulation Of Protein Phosphorylation Penetration Of Zona Pellucida Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing Activation Of MAPKKK Activity Positive Regulation Of Apoptotic Process Involved In Mammary Gland Involution Positive Regulation Of P38MAPK Cascade Regulation Of Acrosome Reaction Regulation Of Phosphorylation Cell Cycle DNA Unwinding Involved In DNA Replication Development Of Secondary Sexual Characteristics Regulation Of P38MAPK Cascade Negative Regulation Of Phosphorylation Regulation Of Phosphorus Metabolic Process Oligosaccharide Biosynthetic Process	Histone MRNA Metabolic Process Nuclear MRNA Surveillance RNA Surveillance Histone MRNA Catabolic Process RRNA Catabolic Process RRNA Metabolic Process Maturation Of 5.8S RRNA Nuclear-transcribed MRNA Catabolic Process NcRNA Metabolic Process MRNA Catabolic Process Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay MRNA Metabolic Process RNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nucleic Acid Phosphodiester Bond Hydrolysis Ribonucleoprotein Complex Biogenesis Regulation Of Cell Growth Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription Aromatic Compound Catabolic Process RNA Phosphodiester Bond Hydrolysis Positive Regulation Of Cell Growth RRNA Processing Nuclear Polyadenylation-dependent RRNA Catabolic Process CUT Catabolic Process Regulation Of Growth Ribosome Biogenesis Cellular Metabolic Process Protein Autophosphorylation DNA Deamination Positive Regulation Of Growth Dosage Compensation By Inactivation Of X Chromosome Cellular Macromolecule Catabolic Process Intracellular MRNA Localization Dosage Compensation
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