TTC3 and ATF7IP

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
HPRD (two hybrid)

		TTC3	ATF7IP
Gene Name		tetratricopeptide repeat domain 3	activating transcription factor 7 interacting protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Vacuole	Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity	Transcription Corepressor Activity Protein Binding ATPase Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cell Morphogenesis Involved In Differentiation Negative Regulation Of Neuron Differentiation Protein K48-linked Ubiquitination	Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA Methylation Chromatin Organization Transcription, DNA-templated Viral Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly
Pathways			Chromatin modifying enzymes Chromatin organization PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Eye color traits ( 20463881)	Prostate-specific antigen levels ( 23359319) Testicular germ cell cancer ( 20543847) Testicular germ cell tumor ( 23666240)
Protein-Protein Interactions		4 interactors: AKT1 ATF7IP UBE2D2 UBE3A	68 interactors: A2M ACTB ACTG1 AP1B1 CADM1 CEP250 COL4A2 CREB1 CSPG4 DISC1 DMTF1 DNM2 EPG5 FLNB FLT4 GMEB1 GTF2E2 GTF2F1 GTF2H1 HEYL HLA-B HSPG2 KIF13A KRT7 LAMA4 LAMA5 LAMC1 LUC7L2 MACF1 MBD1 MCAM MED4 MRI1 NOMO1 NPR1 PAPPA PAPPA2 PCDH1 PEX6 PIAS3 PKD1 PLEKHB2 POLR2C POLR2D POLR2G PRSS8 PSG3 QRICH1 RPS3A RRBP1 SENP3 SETDB1 SLC12A4 SMAD4 SP1 SPTBN1 SREBF2 STBD1 STRN SUMO3 SUSD1 SVEP1 TRIP12 TTC3 UBE2I ZBTB6 ZNF350 ZNF518A
Entrez ID		7267	55729
HPRD ID		03773	09811
Ensembl ID		ENSG00000182670	ENSG00000171681
Uniprot IDs		P53804	B3KNI7 B3KQF8 F5GX74 G3V1U0 Q6VMQ6
PDB IDs			2RPQ
Enriched GO Terms of Interacting Partners?		Protein K48-linked Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Catabolic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Sperm Entry Glycogen Cell Differentiation Involved In Embryonic Placenta Development Protein Polyubiquitination Negative Regulation Of Plasma Membrane Long-chain Fatty Acid Transport Negative Regulation Of Fatty Acid Beta-oxidation Positive Regulation Of Transcription, DNA-templated Response To Hypoxia Response To UV-A Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Activation-induced Cell Death Of T Cells Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Regulation Of RNA Metabolic Process Regulation Of Protein Catabolic Process Negative Regulation Of Fatty Acid Oxidation Catabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Glycogen Biosynthetic Process Immune Response-regulating Signaling Pathway Nitric Oxide Biosynthetic Process Negative Regulation Of Cell Size Reproductive Structure Development Gland Development Ubiquitin-dependent Protein Catabolic Process Reproductive System Development Modification-dependent Protein Catabolic Process Spongiotrophoblast Layer Development Negative Regulation Of Release Of Cytochrome C From Mitochondria T Cell Apoptotic Process Regulation Of Fatty Acid Beta-oxidation Positive Regulation Of Nitric-oxide Synthase Activity Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Viral Process Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Blood Vessel Endothelial Cell Migration	Transcription Initiation From RNA Polymerase II Promoter Viral Process Positive Regulation Of Viral Transcription Cell Differentiation DNA-templated Transcription, Initiation Transcription Elongation From RNA Polymerase II Promoter 7-methylguanosine MRNA Capping Regulation Of Viral Transcription 7-methylguanosine RNA Capping Positive Regulation Of Viral Process Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Elongation RNA Biosynthetic Process Developmental Process Transcription, DNA-templated Anatomical Structure Development Regulation Of Viral Process Post-Golgi Vesicle-mediated Transport Macromolecule Biosynthetic Process Transcription-coupled Nucleotide-excision Repair Gene Expression RNA Metabolic Process Extracellular Matrix Disassembly Cellular Macromolecule Biosynthetic Process Anatomical Structure Morphogenesis System Development Cell Junction Assembly Cardiovascular System Development Stem Cell Differentiation Anatomical Structure Formation Involved In Morphogenesis Biosynthetic Process Nervous System Development Neurogenesis Angiogenesis Positive Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Golgi To Plasma Membrane Protein Transport Somatic Stem Cell Maintenance Protein Sumoylation Positive Regulation Of Gene Expression Multicellular Organismal Development Generation Of Neurons Stem Cell Development Blood Vessel Development Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Cellular Biosynthetic Process Nucleobase-containing Compound Metabolic Process Axon Guidance Golgi Vesicle Transport Vasculature Development
Tagcloud ?		cbr1 david degs downloaded dyrk1a egr1 encyclopedia geo gse hmgn1 hypergeometric interrogate itsn1 kegg kyoto macromolecular multiarray mycmax mzf1 nfe2 nfy olf1 ominibus pax5 rma rp58 son srebp1 tmem50b	acgh adherent cce cd15 cd29 cd44 cd90 continuously csmd1 cultivation cytokeratins cytometric devastating doubling explant grin2b hypercalcemia hypercalcemic karyotype lentiviral oligo outgrowth paralleled park2 proliferating sccoht similarities subpopulations vimentin
Tagcloud (Difference) ?		cbr1 david degs downloaded dyrk1a egr1 encyclopedia geo gse hmgn1 hypergeometric interrogate itsn1 kegg kyoto macromolecular multiarray mycmax mzf1 nfe2 nfy olf1 ominibus pax5 rma rp58 son srebp1 tmem50b	acgh adherent cce cd15 cd29 cd44 cd90 continuously csmd1 cultivation cytokeratins cytometric devastating doubling explant grin2b hypercalcemia hypercalcemic karyotype lentiviral oligo outgrowth paralleled park2 proliferating sccoht similarities subpopulations vimentin
Tagcloud (Intersection) ?