ATF7IP and GMEB1

Number of citations of the paper that reports this interaction (PubMedID 15231748)
54

Data Source:
HPRD (two hybrid)

		ATF7IP	GMEB1
Description		activating transcription factor 7 interacting protein	glucocorticoid modulatory element binding protein 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Regulator Complex Cytosol Nuclear Body	Chromatin Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Transcription Coregulator Activity Transcription Corepressor Activity Protein Binding ATP Hydrolysis Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Sequence-specific DNA Binding Metal Ion Binding Hsp27 Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Methylation-dependent Constitutive Heterochromatin Formation Regulation Of DNA-templated Transcription Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways		PKMTs methylate histone lysines Regulation of endogenous retroelements by KRAB-ZFP proteins Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
Drugs
Diseases
GWAS		Breast cancer ( 24143190) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Height ( 31562340 33713608) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Leukocyte telomere length ( 32109421) Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Prostate-specific antigen levels ( 23359319) Testicular germ cell cancer ( 20543847) Testicular germ cell tumor ( 23666240 28604728 28604732)	Basophil count ( 32888494)
Interacting Genes		71 interacting genes: A2M ACTB ACTG1 AP1B1 CADM1 CEP250 COL4A2 CREB1 CREBBP CSPG4 DISC1 DMTF1 DNM2 EHMT2 EPG5 FLNB FLT4 GMEB1 GTF2E2 GTF2F1 GTF2H1 HEYL HLA-B HMGB1 HSPG2 KIF13A KRT7 LAMA4 LAMA5 LAMC1 LUC7L2 MACF1 MBD1 MCAM MED4 MRI1 NOMO1 NPR1 PAPPA PAPPA2 PCDH1 PEX6 PIAS3 PKD1 PLEKHB2 POLR2C POLR2D POLR2G PRSS8 PSG3 QRICH1 RPS3A RRBP1 SENP3 SETDB1 SLC12A4 SMAD4 SP1 SPTBN1 SREBF2 STBD1 STRN SUMO2 SUSD1 SVEP1 TRIP12 TTC3 UBE2I ZBTB6 ZNF350 ZNF518A	16 interacting genes: ATF7IP CASP8 CASP9 CREBBP DNMT3L GMEB2 MX1 NCOA2 RAD51 SMAD1 SMAD3 SNIP1 SPOP TRIM55 TRIM63 UBE2I
Entrez ID		55729	10691
HPRD ID		09811	16059
Ensembl ID		ENSG00000171681	ENSG00000162419
Uniprot IDs		B3KNI7 B3KQF8 Q6VMQ6	B1AT47 B2RCN8 Q9Y692
PDB IDs		2RPQ	1OQJ
Enriched GO Terms of Interacting Partners?		Transcription By RNA Polymerase II DNA-templated Transcription Morphogenesis Of A Polarized Epithelium Transcription Initiation At RNA Polymerase II Promoter Nucleoplasm DNA-templated Transcription Initiation Basement Membrane Laminin-11 Complex Laminin-10 Complex Lymph Vessel Morphogenesis RNA Polymerase II, Core Complex Nucleobase-containing Compound Biosynthetic Process SUMO Transferase Activity Regulation Of Transepithelial Transport Dense Body Regulation Of Multicellular Organismal Development Nuclear Thyroid Hormone Receptor Binding Presynaptic Cytosol Macromolecule Biosynthetic Process Postsynaptic Cytosol Structural Constituent Of Postsynaptic Actin Cytoskeleton Maintenance Of Blood-brain Barrier Proximal Tubule Development Focal Adhesion DNA-directed RNA Polymerase Complex Golgi To Plasma Membrane Protein Transport Histone H3K9me2 Methyltransferase Activity DNA Methylation-dependent Constitutive Heterochromatin Formation Extracellular Exosome Positive Regulation Of Endothelial Cell Proliferation Regulation Of Transcription By RNA Polymerase II Histone H3K9 Methyltransferase Activity Nucleus	Nucleus Transcription Regulator Complex MiRNA Processing Response To Anesthetic Identical Protein Binding Nuclear Receptor Binding Heteromeric SMAD Protein Complex SMAD Protein Complex DEAD/H-box RNA Helicase Binding Response To Cobalt Ion Chromatin Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Co-SMAD Binding Primary MiRNA Processing Regulation Of Metabolic Process I-SMAD Binding Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Execution Phase Of Apoptosis Ubiquitin Protein Ligase Binding Regulation Of Macromolecule Metabolic Process Transcription Coregulator Activity SMAD Protein Signal Transduction Nucleoplasm Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Double-strand Break Repair Nuclear Body Positive Regulation Of Cartilage Development Enzyme Binding Cytoplasm Cellular Response To Radiation DNA Methylation-dependent Constitutive Heterochromatin Formation Negative Regulation Of Cardiac Muscle Hypertrophy Protein-containing Complex Ureteric Bud Development Negative Regulation Of Muscle Hypertrophy Meiosis I Transcription Regulator Inhibitor Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding Response To External Biotic Stimulus Cytosol Caspase Complex Response To Steroid Hormone Post-translational Protein Modification Chromatin Binding Negative Regulation Of DNA-templated Transcription Transcription Coactivator Binding Negative Regulation Of RNA Biosynthetic Process Mesonephric Epithelium Development Mesonephric Tubule Development
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