ATF7IP and NPR1

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
HPRD (two hybrid)

		ATF7IP	NPR1
Gene Name		activating transcription factor 7 interacting protein	natriuretic peptide receptor 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm	Integral Component Of Plasma Membrane Receptor Complex
	Molecular Function	Transcription Corepressor Activity Protein Binding ATPase Activity	Guanylate Cyclase Activity Protein Kinase Activity ATP Binding GTP Binding G-protein Coupled Peptide Receptor Activity Natriuretic Peptide Receptor Activity Peptide Hormone Binding Protein Kinase Binding Hormone Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA Methylation Chromatin Organization Transcription, DNA-templated Viral Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly	CGMP Biosynthetic Process Protein Phosphorylation Cell Surface Receptor Signaling Pathway Receptor Guanylyl Cyclase Signaling Pathway G-protein Coupled Receptor Signaling Pathway Body Fluid Secretion Regulation Of Blood Pressure Negative Regulation Of Angiogenesis Negative Regulation Of Cell Growth Positive Regulation Of CGMP Biosynthetic Process Intracellular Signal Transduction Positive Regulation Of Urine Volume Positive Regulation Of Renal Sodium Excretion Regulation Of Vasodilation Dopamine Metabolic Process Regulation Of Vascular Permeability Negative Regulation Of Smooth Muscle Cell Proliferation Regulation Of Blood Vessel Size
Pathways		Chromatin modifying enzymes Chromatin organization PKMTs methylate histone lysines
Drugs			Nitroprusside Nitroglycerin Isosorbide Dinitrate Amyl Nitrite Erythrityl Tetranitrate Nesiritide
Diseases
GWAS		Prostate-specific antigen levels ( 23359319) Testicular germ cell cancer ( 20543847) Testicular germ cell tumor ( 23666240)
Protein-Protein Interactions		68 interactors: A2M ACTB ACTG1 AP1B1 CADM1 CEP250 COL4A2 CREB1 CSPG4 DISC1 DMTF1 DNM2 EPG5 FLNB FLT4 GMEB1 GTF2E2 GTF2F1 GTF2H1 HEYL HLA-B HSPG2 KIF13A KRT7 LAMA4 LAMA5 LAMC1 LUC7L2 MACF1 MBD1 MCAM MED4 MRI1 NOMO1 NPR1 PAPPA PAPPA2 PCDH1 PEX6 PIAS3 PKD1 PLEKHB2 POLR2C POLR2D POLR2G PRSS8 PSG3 QRICH1 RPS3A RRBP1 SENP3 SETDB1 SLC12A4 SMAD4 SP1 SPTBN1 SREBF2 STBD1 STRN SUMO3 SUSD1 SVEP1 TRIP12 TTC3 UBE2I ZBTB6 ZNF350 ZNF518A	5 interactors: ATF7IP NPPA NPPB NPPC PRKG1
Entrez ID		55729	4881
HPRD ID		09811	00165
Ensembl ID		ENSG00000171681	ENSG00000169418
Uniprot IDs		B3KNI7 B3KQF8 F5GX74 G3V1U0 Q6VMQ6	P16066
PDB IDs		2RPQ
Enriched GO Terms of Interacting Partners?		Transcription Initiation From RNA Polymerase II Promoter Viral Process Positive Regulation Of Viral Transcription Cell Differentiation DNA-templated Transcription, Initiation Transcription Elongation From RNA Polymerase II Promoter 7-methylguanosine MRNA Capping Regulation Of Viral Transcription 7-methylguanosine RNA Capping Positive Regulation Of Viral Process Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Elongation RNA Biosynthetic Process Developmental Process Transcription, DNA-templated Anatomical Structure Development Regulation Of Viral Process Post-Golgi Vesicle-mediated Transport Macromolecule Biosynthetic Process Transcription-coupled Nucleotide-excision Repair Gene Expression RNA Metabolic Process Extracellular Matrix Disassembly Cellular Macromolecule Biosynthetic Process Anatomical Structure Morphogenesis System Development Cell Junction Assembly Cardiovascular System Development Stem Cell Differentiation Anatomical Structure Formation Involved In Morphogenesis Biosynthetic Process Nervous System Development Neurogenesis Angiogenesis Positive Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Golgi To Plasma Membrane Protein Transport Somatic Stem Cell Maintenance Protein Sumoylation Positive Regulation Of Gene Expression Multicellular Organismal Development Generation Of Neurons Stem Cell Development Blood Vessel Development Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Cellular Biosynthetic Process Nucleobase-containing Compound Metabolic Process Axon Guidance Golgi Vesicle Transport Vasculature Development	Regulation Of Blood Vessel Size Regulation Of Tube Size Receptor Guanylyl Cyclase Signaling Pathway CGMP Biosynthetic Process CGMP Metabolic Process Cyclic Purine Nucleotide Metabolic Process Cyclic Nucleotide Biosynthetic Process Blood Circulation Cyclic Nucleotide Metabolic Process Purine Nucleotide Biosynthetic Process Ribose Phosphate Biosynthetic Process Ribonucleotide Metabolic Process Nucleotide Biosynthetic Process Purine Nucleotide Metabolic Process Ribose Phosphate Metabolic Process Regulation Of Vasodilation Nucleotide Metabolic Process Regulation Of Growth Nucleobase-containing Small Molecule Metabolic Process Growth Plate Cartilage Chondrocyte Proliferation Negative Regulation Of Cell Growth Regulation Of Muscle Contraction Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Blood Pressure Negative Regulation Of Oocyte Maturation Organophosphate Metabolic Process Regulation Of Generation Of L-type Calcium Current Positive Regulation Of Delayed Rectifier Potassium Channel Activity Negative Regulation Of Oocyte Development Phosphate-containing Compound Metabolic Process Negative Regulation Of Growth Regulation Of Atrial Cardiac Muscle Cell Membrane Repolarization Muscle System Process Growth Plate Cartilage Chondrocyte Differentiation Regulation Of High Voltage-gated Calcium Channel Activity Positive Regulation Of Cardiac Muscle Contraction Response To Hypoxia Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Regulation Of Delayed Rectifier Potassium Channel Activity Response To Muscle Stretch Relaxation Of Vascular Smooth Muscle Regulation Of Cell Growth CGMP-mediated Signaling Relaxation Of Smooth Muscle Negative Regulation Of Platelet Aggregation Positive Regulation Of Striated Muscle Contraction Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Renal Sodium Excretion Negative Regulation Of Smooth Muscle Contraction Positive Regulation Of Urine Volume
Tagcloud ?		acgh adherent cce cd15 cd29 cd44 cd90 continuously csmd1 cultivation cytokeratins cytometric devastating doubling explant grin2b hypercalcemia hypercalcemic karyotype lentiviral oligo outgrowth paralleled park2 proliferating sccoht similarities subpopulations vimentin	advantages asset bands bzip complemented elusive ethylene interacting interested isolating offers overexpressing oxylipin powerful proteolytically pull purification purifying researchers salicylic stimulus tag tagged tagging tap tga2 tga5 tga6 xenobiotic
Tagcloud (Difference) ?		acgh adherent cce cd15 cd29 cd44 cd90 continuously csmd1 cultivation cytokeratins cytometric devastating doubling explant grin2b hypercalcemia hypercalcemic karyotype lentiviral oligo outgrowth paralleled park2 proliferating sccoht similarities subpopulations vimentin	advantages asset bands bzip complemented elusive ethylene interacting interested isolating offers overexpressing oxylipin powerful proteolytically pull purification purifying researchers salicylic stimulus tag tagged tagging tap tga2 tga5 tga6 xenobiotic
Tagcloud (Intersection) ?