TPM1 and PKD2

  • Number of citations of the paper that reports this interaction (PMID 12527301)
  • 14
  • Data Source:
  • HPRD (in vivo, two hybrid, in vitro)

TPM1

PKD2

Gene Name tropomyosin 1 (alpha) polycystic kidney disease 2 (autosomal dominant)
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 18 interactors: ACTB C1orf216 CAGE1 EGFR EPB41 GOLGA2 JUN KXD1 MAD1L1 PKD2 S100A2 SYCE1 TFPT TMOD2 TNNT1 TNNT2 TPM2 TPM4 15 interactors: ACTN2 CD2AP DIAPH1 HAX1 KRT40 KRTAP10-3 KRTAP10-8 MAGEA8 PACS1 PACS2 PKD1 PLSCR1 TNNI3 TPM1 TRPC1
Entrez ID 7168 5311
HPRD ID 01839 01437
Ensembl ID ENSG00000140416 ENSG00000118762
Uniprot IDs B7Z596 B7Z722 D9YZV4 D9YZV5 D9YZV7 F5H7S3 H7BYY1 O15513 P09493 Q6ZN40 Q13563 Q9UEU6
PDB IDs 2KLD 2KLE 2KQ6 2Y4Q 3HRN 3HRO
Enriched GO Terms of Interacting Partners?
Tagcloud ?
abp1  abp1p  act1  actin  cap1  cap2  capping  cerevisiae  cytoskeleton  deleterious  draw  extreme  fimbrin  inviability  lacking  lethal  lethality  null  organization  phenotypes  physiology  redundancy  redundant  sac6  saccharomyces  surprising  synthetic  tropomyosin  viable 
acts  adpkd  autosomal  chaperone  coil  coiled  complexing  determinant  disrupted  distal  glycoform  gps  heterozygotes  illustrating  inherited  interbreeding  maturation  mature  missense  nephropathy  nonequimolar  pathogenic  pc1  pc2  pkd1  polycystic  polycystin  progressive  severity 
Tagcloud (Difference) ?
abp1  abp1p  act1  actin  cap1  cap2  capping  cerevisiae  cytoskeleton  deleterious  draw  extreme  fimbrin  inviability  lacking  lethal  lethality  null  organization  phenotypes  physiology  redundancy  redundant  sac6  saccharomyces  surprising  synthetic  tropomyosin  viable 
acts  adpkd  autosomal  chaperone  coil  coiled  complexing  determinant  disrupted  distal  glycoform  gps  heterozygotes  illustrating  inherited  interbreeding  maturation  mature  missense  nephropathy  nonequimolar  pathogenic  pc1  pc2  pkd1  polycystic  polycystin  progressive  severity 
Tagcloud (Intersection) ?