TPBG and GIPC1

Number of citations of the paper that reports this interaction (PubMedID 11798178)
0

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		TPBG	GIPC1
Description		trophoblast glycoprotein	GIPC PDZ domain containing family member 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Plasma Membrane Cell Surface Membrane Dendrite Axon Terminus	Cytoplasm Cytosol Cell Cortex Synaptic Vesicle Vesicle Membrane Membrane Cytoplasmic Vesicle Dendritic Spine Dendritic Shaft Extracellular Exosome Schaffer Collateral - CA1 Synapse Glutamatergic Synapse
	Molecular Function		Actin Binding Signaling Receptor Binding Protein Binding Myosin Binding Identical Protein Binding Cadherin Binding
	Biological Process	Cell Adhesion Negative Regulation Of Cell Population Proliferation Olfactory Learning Positive Regulation Of Chemotaxis Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Synaptic Transmission, GABAergic Positive Regulation Of Synapse Assembly Cell Chemotaxis Positive Regulation Of ERK1 And ERK2 Cascade Protein Localization To Plasma Membrane Negative Regulation Of Canonical Wnt Signaling Pathway Mesenchymal Cell Migration Dendrite Arborization	Protein Targeting G Protein-coupled Receptor Signaling Pathway Chemical Synaptic Transmission Glutamate Secretion Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Protein Stability Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Cytokinesis Endothelial Cell Migration Positive Regulation Of Melanin Biosynthetic Process Regulation Of Synaptic Plasticity Cellular Response To Interleukin-7 Presynaptic Modulation Of Chemical Synaptic Transmission
Pathways			FGFR1b ligand binding and activation FGFR1c ligand binding and activation TGFBR3 regulates TGF-beta signaling TGFBR3 regulates FGF2 signaling
Drugs
Diseases
GWAS		Schizophrenia, bipolar disorder or recurrent major depressive disorder ( 34099189)	Femur bone mineral density x serum urate levels interaction ( 34046847) Kidney stones ( 31729369)
Interacting Genes		1 interacting genes: GIPC1	37 interacting genes: ACTN1 ADRB1 CARD10 CD93 DDIT3 DRD2 DRD3 FZD3 GSK3B IGF1R ITGA5 ITGA6 KCNJ6 KIF1B LHCGR LPAR1 LPAR2 LRP1 LRP2 LRP8 MYO6 NRP1 NTRK1 NTRK2 PLEKHA2 RGS1 RGS19 SDC4 SEMA4B SEMA4C SLC2A1 TGFBR3 TPBG TYRP1 VANGL2 ZFPM1 ZNF408
Entrez ID		7162	10755
HPRD ID		01837	05462
Ensembl ID		ENSG00000146242	ENSG00000123159
Uniprot IDs		Q13641	A8K2I7 O14908
PDB IDs		4CNC 4CNM 6HBY
Enriched GO Terms of Interacting Partners?		Cellular Response To Interleukin-7 Regulation Of Melanin Biosynthetic Process Response To Interleukin-7 Positive Regulation Of Melanin Biosynthetic Process Glutamate Secretion Myosin Binding Dendritic Shaft Presynaptic Modulation Of Chemical Synaptic Transmission Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Cytokinesis Vesicle Membrane Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Acidic Amino Acid Transport Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Dicarboxylic Acid Transport Endothelial Cell Migration Regulation Of Cytokinesis Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Cell Division Schaffer Collateral - CA1 Synapse Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Amino Acid Transport Negative Regulation Of Protein Catabolic Process Synaptic Vesicle Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Dendritic Spine Cell Cortex Regulation Of Cell Division Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Synaptic Plasticity Protein Targeting Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Cell Cycle Process Carboxylic Acid Transport Organic Acid Transport Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Cadherin Binding Regulation Of Cellular Response To Growth Factor Stimulus Organic Anion Transport Trans-synaptic Signaling Positive Regulation Of Cell Cycle Synaptic Signaling Chemical Synaptic Transmission Regulation Of Protein Catabolic Process Actin Binding Regulation Of Protein Stability Negative Regulation Of Catabolic Process	Plasma Membrane Glutamatergic Synapse Membrane Cell Migration Regulation Of Locomotion Regulation Of Signal Transduction Regulation Of Cell Communication Positive Regulation Of Intracellular Signal Transduction Regulation Of Signaling Regulation Of Cell Migration Receptor Complex Positive Regulation Of Signal Transduction Axon Regulation Of Cell Motility Cell Motility PDZ Domain Binding Cell Projection Organization Positive Regulation Of MAPK Cascade Positive Regulation Of Cell Communication Positive Regulation Of Signaling Cell Surface Anatomical Structure Formation Involved In Morphogenesis Signal Transduction Regulation Of MAPK Cascade Negative Regulation Of Signal Transduction Positive Regulation Of Nervous System Development Developmental Process Positive Regulation Of Multicellular Organismal Process Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Intracellular Signal Transduction Regulation Of Nervous System Development Positive Regulation Of Cellular Component Organization Endocytic Vesicle Positive Regulation Of Locomotion Dendrite Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Regulation Of Developmental Process Regulation Of Apoptotic Process Neural Tube Closure Anatomical Structure Morphogenesis Regulation Of Programmed Cell Death Tube Closure Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Migration Insulin-like Growth Factor I Binding Positive Regulation Of Developmental Process Regulation Of Multicellular Organismal Process Positive Regulation Of Cell Motility
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?