TPBG and GIPC1

Number of citations of the paper that reports this interaction (PMID 11798178)
11

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		TPBG	GIPC1
Gene Name		trophoblast glycoprotein	GIPC PDZ domain containing family, member 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Integral Component Of Plasma Membrane Cell Surface	Cytoplasm Cytosol Brush Border Cell Cortex Synaptic Vesicle Vesicle Membrane Membrane Cytoplasmic Membrane-bounded Vesicle Endocytic Vesicle Dendritic Spine Dendritic Shaft Extracellular Vesicular Exosome
	Molecular Function		Actin Binding Receptor Binding Protein Binding Myosin Binding PDZ Domain Binding Protein Homodimerization Activity
	Biological Process	Cell Adhesion	Protein Targeting G-protein Coupled Receptor Signaling Pathway Synaptic Transmission Glutamate Secretion Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Protein Stability Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Cytokinesis Endothelial Cell Migration Regulation Of Synaptic Plasticity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: GIPC1	31 interactors: ACTN1 ADRB1 CD93 DDIT3 DRD2 DRD3 FZD3 GSK3B IGF1R ITGA5 ITGA6 KIF1B LHCGR LRP1 LRP2 LRP8 MYO6 NRP1 NTRK1 NTRK2 RGS1 RGS19 SDC4 SEMA4B SEMA4C SLC2A1 TGFBR3 TPBG TYRP1 ZFPM1 ZNF408
Entrez ID		7162	10755
HPRD ID		01837	05462
Ensembl ID		ENSG00000146242	ENSG00000123159
Uniprot IDs		A8K555 Q13641	A8K2I7 O14908
PDB IDs
Enriched GO Terms of Interacting Partners?		Glutamate Secretion Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Cytokinesis Acid Secretion Regulation Of Cytokinesis Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Cellular Protein Catabolic Process Endothelial Cell Migration Dicarboxylic Acid Transport Epithelial Cell Migration Epithelium Migration Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Protein Catabolic Process Positive Regulation Of Cell Division Regulation Of Protein Stability Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Amino Acid Transport Regulation Of Synaptic Plasticity Ameboidal-type Cell Migration Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Cell Cycle Process Regulation Of Cell Division Positive Regulation Of Cell Cycle Carboxylic Acid Transport Regulation Of Synaptic Transmission Organic Acid Transport Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Regulation Of Protein Catabolic Process Regulation Of Protein Processing Protein Targeting Organic Anion Transport Posttranscriptional Regulation Of Gene Expression Regulation Of Cell Cycle Process Secretion By Cell	Response To External Stimulus Regulation Of Signaling Regulation Of Phosphorus Metabolic Process Regulation Of Adenylate Cyclase Activity Regulation Of Cyclase Activity Positive Regulation Of Phosphorylation Response To Abiotic Stimulus Cell Surface Receptor Signaling Pathway Cell Communication System Development Regulation Of CAMP Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Anatomical Structure Development Positive Regulation Of Metabolic Process Developmental Process Cognition Regulation Of CAMP Metabolic Process Signaling Regulation Of Signal Transduction Signal Transduction Multicellular Organismal Development Movement Of Cell Or Subcellular Component Cell Differentiation Positive Regulation Of Signal Transduction Regulation Of Phosphorylation Learning Or Memory Cell Migration Negative Regulation Of Signal Transduction Activation Of Adenylate Cyclase Activity Anatomical Structure Morphogenesis Regulation Of Cell Development Response To Radiation Tissue Development Cellular Response To Stimulus Regulation Of Synaptic Transmission Cell Motility Regulation Of Apoptotic Process Negative Regulation Of Signaling Positive Regulation Of Adenylate Cyclase Activity Organ Development Response To Stimulus Response To Wounding Positive Regulation Of Cell Development Cell Morphogenesis Involved In Differentiation Response To Light Stimulus Positive Regulation Of Protein Phosphorylation Regulation Of Cell Death Locomotion Regulation Of Cell Differentiation Nervous System Development
Tagcloud ?		5q 5q31 activin antiadhesive antiangiogenic antiproliferative cytogenetically cytopenias del deleted differentiating dramatic erythroblast erythroblasts erythropoiesis gypa hba2 ineffective klf1 lenalidomide mdss pleiotropic ppic q31 q32 remarkable sparc underlie vsig4	adrb1 alpha5 appl1 assembles cargoes deafness dimerizing drd2 factorbeta gh1 gh2 gipc2 gipc3 gipcs gpcrs hbc lrp1 myo6 nonsyndromic nrp1 ntrk1 pdz rgs19 rtks sdc4 sema4c tgfbetar3 vangl2
Tagcloud (Difference) ?		5q 5q31 activin antiadhesive antiangiogenic antiproliferative cytogenetically cytopenias del deleted differentiating dramatic erythroblast erythroblasts erythropoiesis gypa hba2 ineffective klf1 lenalidomide mdss pleiotropic ppic q31 q32 remarkable sparc underlie vsig4	adrb1 alpha5 appl1 assembles cargoes deafness dimerizing drd2 factorbeta gh1 gh2 gipc2 gipc3 gipcs gpcrs hbc lrp1 myo6 nonsyndromic nrp1 ntrk1 pdz rgs19 rtks sdc4 sema4c tgfbetar3 vangl2
Tagcloud (Intersection) ?