TNNI3 and RCAN3

Number of citations of the paper that reports this interaction (PMID 16516408)
2

Data Source:
BioGRID (protein complementation assay)
HPRD (two hybrid, in vitro)

		TNNI3	RCAN3
Gene Name		troponin I type 3 (cardiac)	RCAN family member 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Troponin Complex Sarcomere
	Molecular Function	Actin Binding Protein Binding Calcium Channel Inhibitor Activity Protein Kinase Binding Protein Domain Specific Binding Troponin C Binding Troponin T Binding Metal Ion Binding Calcium-dependent Protein Binding	RNA Binding Troponin I Binding
	Biological Process	Vasculogenesis Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions Cellular Calcium Ion Homeostasis Regulation Of Smooth Muscle Contraction Heart Development Muscle Filament Sliding Negative Regulation Of ATPase Activity Ventricular Cardiac Muscle Tissue Morphogenesis Heart Contraction Cardiac Muscle Contraction	Anatomical Structure Morphogenesis Calcium-mediated Signaling
Pathways		Striated Muscle Contraction
Drugs		N-(6-Aminohexyl)-5-Chloro-1-Naphthalenesulfonamide
Diseases
GWAS
Protein-Protein Interactions		14 interactors: ACTA1 LYST PAPPA PKD2 PKD2L1 PRKCA RCAN3 TNNC1 TNNC2 TNNI3K TNNT1 TNNT2 TRIM55 TRIM63	2 interactors: TNNI3 ZDHHC17
Entrez ID		7137	11123
HPRD ID		11769	05792
Ensembl ID		ENSG00000129991	ENSG00000117602
Uniprot IDs		P19429 Q6FGX2	E3VWE2 E5L4P0 Q9UKA8
PDB IDs		1J1D 1J1E 1LXF 1MXL 1OZS 2KGB 2KRD 2L1R
Enriched GO Terms of Interacting Partners?		Actin-myosin Filament Sliding Muscle Filament Sliding Actin-mediated Cell Contraction Actin Filament-based Movement Muscle Contraction Muscle System Process Regulation Of Muscle Contraction Skeletal Muscle Contraction Musculoskeletal Movement Movement Of Cell Or Subcellular Component Negative Regulation Of ATPase Activity Skeletal Muscle Adaptation Striated Muscle Contraction Actin Filament-based Process Muscle Tissue Development Positive Regulation Of Blood Vessel Endothelial Cell Migration Response To Inorganic Substance Detection Of Abiotic Stimulus Ion Homeostasis Response To Mechanical Stimulus Regulation Of ATPase Activity Heart Morphogenesis Response To Abiotic Stimulus Ventricular Cardiac Muscle Tissue Morphogenesis Regulation Of Blood Vessel Endothelial Cell Migration Detection Of Mechanical Stimulus Ventricular Cardiac Muscle Tissue Development Cardiac Muscle Tissue Morphogenesis Positive Regulation Of Endothelial Cell Migration Muscle Organ Development Positive Regulation Of Endothelial Cell Proliferation Cellular Calcium Ion Homeostasis Metanephric Cortex Development Metanephric Cortical Collecting Duct Development Regulation Of Muscle Filament Sliding Speed Positive Regulation Of Dense Core Granule Biogenesis Muscle Tissue Morphogenesis Calcium Ion Homeostasis Striated Muscle Tissue Development Muscle Organ Morphogenesis Cardiac Ventricle Morphogenesis Response To Metal Ion Myofibril Assembly Positive Regulation Of Epithelial Cell Migration Response To Interleukin-1 Regulation Of Endothelial Cell Proliferation Protein Kinase D Signaling Metanephric Smooth Muscle Tissue Development Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Skeletal Muscle Fiber Adaptation	Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions Negative Regulation Of ATPase Activity Lipoprotein Transport Neurological System Process Involved In Regulation Of Systemic Arterial Blood Pressure Magnesium Ion Transport Protein Palmitoylation Muscle Filament Sliding Actin-myosin Filament Sliding Regulation Of ATPase Activity Actin-mediated Cell Contraction Ventricular Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Contraction Regulation Of Smooth Muscle Contraction Ventricular Cardiac Muscle Tissue Development Cardiac Muscle Tissue Morphogenesis Actin Filament-based Movement Muscle Tissue Morphogenesis Heart Contraction Muscle Organ Morphogenesis Cardiac Ventricle Morphogenesis Striated Muscle Contraction Regulation Of Systemic Arterial Blood Pressure Vasculogenesis Cardiac Ventricle Development Protein Lipidation Lipoprotein Biosynthetic Process
Tagcloud ?		activin bmp4 cardiomyogenic discovering dish enthusiasm exploiting hesc hipsc homeodomain homogeneity hpscs implement iroquois irx irx4 mlc2a mlc2v myosin offering passaged pluripotent repairing robustly standardization subpopulation technically tnnt2 troponin	acd acd1 acd21 acd6 acds analysing bidirectional bioinformatic calcineurin clic collocate duplication eukarya evolved fibre invertebrates nat nfatc rcan2 remodelling rounds runx scenario segmental timely transposable unmethylated vertebrates
Tagcloud (Difference) ?		activin bmp4 cardiomyogenic discovering dish enthusiasm exploiting hesc hipsc homeodomain homogeneity hpscs implement iroquois irx irx4 mlc2a mlc2v myosin offering passaged pluripotent repairing robustly standardization subpopulation technically tnnt2 troponin	acd acd1 acd21 acd6 acds analysing bidirectional bioinformatic calcineurin clic collocate duplication eukarya evolved fibre invertebrates nat nfatc rcan2 remodelling rounds runx scenario segmental timely transposable unmethylated vertebrates
Tagcloud (Intersection) ?