TNNT2 and MORF4L2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TNNT2	MORF4L2
Gene Name		troponin T type 2 (cardiac)	mortality factor 4 like 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Troponin Complex Striated Muscle Thin Filament Sarcomere	Nucleoplasm Nucleolus
	Molecular Function	Actin Binding Structural Constituent Of Cytoskeleton Tropomyosin Binding ATPase Activity Troponin C Binding Troponin I Binding	Protein Binding
	Biological Process	Regulation Of Muscle Contraction Regulation Of Heart Contraction Metabolic Process Muscle Filament Sliding Negative Regulation Of ATPase Activity Positive Regulation Of ATPase Activity Sarcomere Organization Response To Calcium Ion Atrial Cardiac Muscle Tissue Morphogenesis Ventricular Cardiac Muscle Tissue Morphogenesis	DNA Repair Chromatin Organization Transcription, DNA-templated Chromatin Modification Regulation Of Growth Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Striated Muscle Cell Differentiation
Pathways		Striated Muscle Contraction	Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS		Cardiac Troponin-T levels ( 23247143)
Protein-Protein Interactions		10 interactors: APP KDM1A MAP3K5 MORF4L2 NOTCH3 PRKCA TNNC1 TNNI1 TNNI3 TPM1	28 interactors: AES BEND7 CDR2 CEP55 DDIT4L FAM9B GOLGA2 GRAMD3 HDAC1 IKZF1 KLHL3 L3MBTL3 LZTS2 MRFAP1 MRFAP1L1 MRGBP PHC2 PNMA2 RB1 SIN3A THAP1 TLE1 TNIP1 TNNT2 ZBTB10 ZBTB14 ZBTB43 ZBTB7B
Entrez ID		7139	9643
HPRD ID		01844	02326
Ensembl ID		ENSG00000118194	ENSG00000123562
Uniprot IDs		P45379 Q15607	Q15014
PDB IDs		1J1D 1J1E
Enriched GO Terms of Interacting Partners?		Actin-myosin Filament Sliding Muscle Filament Sliding Ventricular Cardiac Muscle Tissue Morphogenesis Actin-mediated Cell Contraction Regulation Of Muscle Contraction Ventricular Cardiac Muscle Tissue Development Cardiac Muscle Tissue Morphogenesis Muscle Tissue Morphogenesis Actin Filament-based Movement Muscle Organ Morphogenesis Cardiac Ventricle Morphogenesis Cardiac Ventricle Development Cardiac Chamber Development Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions Cardiovascular System Development Regulation Of ATPase Activity Cardiac Muscle Tissue Development Muscle Structure Development Cardiac Muscle Contraction Muscle Contraction Heart Morphogenesis Heart Contraction Organ Development Muscle System Process Muscle Organ Development Cellular Calcium Ion Homeostasis Striated Muscle Contraction Calcium Ion Homeostasis Striated Muscle Tissue Development Negative Regulation Of ATPase Activity Muscle Tissue Development Regulation Of Systemic Arterial Blood Pressure Movement Of Cell Or Subcellular Component Anatomical Structure Morphogenesis Cellular Metal Ion Homeostasis Blood Vessel Morphogenesis Cellular Cation Homeostasis Cellular Ion Homeostasis Metal Ion Homeostasis System Development Neurological System Process Involved In Regulation Of Systemic Arterial Blood Pressure Heart Development Blood Vessel Development Cellular Chemical Homeostasis Regulation Of Blood Pressure Vasculature Development Ion Homeostasis Wound Healing Multicellular Organismal Development Anatomical Structure Development	Transcription, DNA-templated RNA Biosynthetic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Biosynthetic Process Chromatin Modification Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Chromatin Organization Negative Regulation Of Signal Transduction Negative Regulation Of Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Signaling Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Binding Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Anoikis Organ Development Cell Cycle Chromosome Organization Nitrogen Compound Metabolic Process Multicellular Organismal Development Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Mitotic Cell Cycle Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Neutrophil Differentiation Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Response To Methylglyoxal Negative Regulation Of Histone H3-K27 Acetylation Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Myeloid Leukocyte Differentiation Positive Regulation Of Cell Cycle Phase Transition Developmental Process Negative Regulation Of Protein Binding Histone Deacetylation
Tagcloud ?		apposition axin2 bending bf bfr bones canonical compromised csa determinant epsilon histomorphometric hz ko littermate loaded loading mar mechanical mineral nfatc1 periosteal periosteum reductions tibia unloaded wnt wnt16 wt
Tagcloud (Difference) ?		apposition axin2 bending bf bfr bones canonical compromised csa determinant epsilon histomorphometric hz ko littermate loaded loading mar mechanical mineral nfatc1 periosteal periosteum reductions tibia unloaded wnt wnt16 wt
Tagcloud (Intersection) ?