PPP1R11 and YAF2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PPP1R11	YAF2
Description		protein phosphatase 1 regulatory inhibitor subunit 11	YY1 associated factor 2
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GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Phosphatase Inhibitor Activity Protein Serine/threonine Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase 1 Binding Transferase Activity Phosphatase Binding Ubiquitin Protein Ligase Activity	DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Cytokine Production Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Defense Response To Gram-positive Bacterium	Regulation Of DNA-templated Transcription Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription
Pathways			RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Anger ( 24489884) Autism spectrum disorder or schizophrenia ( 28540026) Lipid metabolism phenotypes ( 22286219)	Refractive error ( 32231278)
Interacting Genes		10 interacting genes: AKT1 IFT20 LATS1 PPP1CA PPP1CB PPP1CC PPP1R3A UBXN2B VCP YAF2	28 interacting genes: ANP32B CAVIN1 CD300LF DNAAF6 EAF1 GABPB1 IFT57 INO80B LGALS7 LGALS7B MAPRE3 MARK1 MYC MYCN NEDD8 NUTF2 PCDH17 POLR3GL PPP1R11 PTEN SETBP1 SPANXN2 SPANXN3 TLK1 UBC XAGE1B YY1 ZFP42
Entrez ID		6992	10138
HPRD ID		09449	09606
Ensembl ID		ENSG00000204619	ENSG00000015153
Uniprot IDs		A2BEK1 O60927	B4DJQ9 G3V212 Q8IY57
PDB IDs		8DWK 8DWL 8U5G	2D9G
Enriched GO Terms of Interacting Partners?		Glycogen Metabolic Process Energy Reserve Metabolic Process Polysaccharide Metabolic Process PTW/PP1 Phosphatase Complex Regulation Of Generation Of Precursor Metabolites And Energy Carbohydrate Metabolic Process Energy Derivation By Oxidation Of Organic Compounds Response To Radiation Entrainment Of Circadian Clock By Photoperiod Protein Phosphatase 1 Binding Photoperiodism Entrainment Of Circadian Clock Generation Of Precursor Metabolites And Energy Regulation Of Glycogen Biosynthetic Process Response To Light Stimulus Circadian Rhythm Regulation Of Glycogen Metabolic Process Positive Regulation Of Small Molecule Metabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Protein Localization Positive Regulation Of Cellular Component Biogenesis Circadian Regulation Of Gene Expression Postsynapse Regulation Of Organelle Assembly Glutamatergic Synapse Regulation Of Canonical Wnt Signaling Pathway Rhythmic Process Phosphatase Activity Protein Dephosphorylation Protein Serine/threonine Phosphatase Activity Positive Regulation Of Cellular Component Organization Positive Regulation Of Organelle Assembly Regulation Of Synapse Organization Protein Phosphatase Type 1 Complex Regulation Of Translational Initiation Regulation Of Wnt Signaling Pathway Regulation Of Small Molecule Metabolic Process Regulation Of Circadian Rhythm Positive Regulation Of Glycogen Biosynthetic Process Mammary Gland Epithelial Cell Differentiation Positive Regulation Of Protein Localization To Cell Surface Regulation Of Proteolysis Dephosphorylation Phosphate-containing Compound Metabolic Process Phosphoprotein Phosphatase Activity Regulation Of Oxidative Phosphorylation Positive Regulation Of Glial Cell Proliferation Intracellular Signaling Cassette Negative Regulation Of Lipid Catabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway	Nucleoplasm Regulation Of MiRNA Transcription Positive Regulation Of Telomere Maintenance Protein Tag Activity Regulation Of Synaptic Vesicle Clustering Regulation Of DNA Strand Elongation Ino80 Complex Positive Regulation Of Telomere Maintenance In Response To DNA Damage Chromatin Organization Regulation Of MiRNA Metabolic Process
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