PPP1R11

Name	protein phosphatase 1 regulatory inhibitor subunit 11
Structure
Novel Interactors	1 novel interactors: TNF
Interactors	10 interactors: AKT1 IFT20 LATS1 PPP1CA PPP1CB PPP1CC PPP1R3A UBXN2B VCP YAF2
GO Annotations	Cellular Component	Nucleus Cytoplasm
	Molecular Function	Protein Phosphatase Inhibitor Activity Protein Serine/threonine Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase 1 Binding Transferase Activity Phosphatase Binding Ubiquitin Protein Ligase Activity
	Biological Process	Negative Regulation Of Cytokine Production Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Defense Response To Gram-positive Bacterium
GWAS	Anger ( 24489884 ) Autism spectrum disorder or schizophrenia ( 28540026 ) Lipid metabolism phenotypes ( 22286219 )
Entrez ID	6992
HPRD ID	09449
Ensembl ID	ENSG00000204619
Uniprot IDs	A2BEK1 O60927
PDB IDs	8DWK 8DWL 8U5G
GO Terms Enriched among Interactors ?	Glycogen Metabolic Process Energy Reserve Metabolic Process Polysaccharide Metabolic Process PTW/PP1 Phosphatase Complex Regulation Of Generation Of Precursor Metabolites And Energy Carbohydrate Metabolic Process Energy Derivation By Oxidation Of Organic Compounds Response To Radiation Entrainment Of Circadian Clock By Photoperiod Protein Phosphatase 1 Binding Photoperiodism Entrainment Of Circadian Clock Generation Of Precursor Metabolites And Energy Regulation Of Glycogen Biosynthetic Process Response To Light Stimulus Circadian Rhythm Regulation Of Glycogen Metabolic Process Positive Regulation Of Small Molecule Metabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Protein Localization Positive Regulation Of Cellular Component Biogenesis Circadian Regulation Of Gene Expression Postsynapse Regulation Of Organelle Assembly Glutamatergic Synapse Regulation Of Canonical Wnt Signaling Pathway Rhythmic Process Phosphatase Activity Protein Dephosphorylation Protein Serine/threonine Phosphatase Activity Positive Regulation Of Cellular Component Organization Positive Regulation Of Organelle Assembly Regulation Of Synapse Organization Protein Phosphatase Type 1 Complex Regulation Of Translational Initiation Regulation Of Wnt Signaling Pathway Regulation Of Small Molecule Metabolic Process Regulation Of Circadian Rhythm Positive Regulation Of Glycogen Biosynthetic Process Mammary Gland Epithelial Cell Differentiation Positive Regulation Of Protein Localization To Cell Surface Regulation Of Proteolysis Dephosphorylation Phosphate-containing Compound Metabolic Process Phosphoprotein Phosphatase Activity Regulation Of Oxidative Phosphorylation Positive Regulation Of Glial Cell Proliferation Intracellular Signaling Cassette Negative Regulation Of Lipid Catabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway