YAF2 and SPANXN3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		YAF2	SPANXN3
Description		YY1 associated factor 2	SPANX family member N3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol
	Molecular Function	DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription
Pathways		RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Creatine kinase levels ( 29403010)
Interacting Genes		28 interacting genes: ANP32B CAVIN1 CD300LF DNAAF6 EAF1 GABPB1 IFT57 INO80B LGALS7 LGALS7B MAPRE3 MARK1 MYC MYCN NEDD8 NUTF2 PCDH17 POLR3GL PPP1R11 PTEN SETBP1 SPANXN2 SPANXN3 TLK1 UBC XAGE1B YY1 ZFP42	17 interacting genes: APP ATP6V1C2 CAVIN1 CEP70 FAM217B FAM228A HAND2 MEOX2 NEDD4 PBX4 PTGES3L-AARSD1 SDCBP SP4 STAC3 YAF2 ZNF143 ZNF76
Entrez ID		10138	139067
HPRD ID		09606	18092
Ensembl ID		ENSG00000015153	ENSG00000189252
Uniprot IDs		B4DJQ9 G3V212 Q8IY57	Q5MJ09
PDB IDs		2D9G
Enriched GO Terms of Interacting Partners?		Nucleoplasm Regulation Of MiRNA Transcription Positive Regulation Of Telomere Maintenance Protein Tag Activity Regulation Of Synaptic Vesicle Clustering Regulation Of DNA Strand Elongation Ino80 Complex Positive Regulation Of Telomere Maintenance In Response To DNA Damage Chromatin Organization Regulation Of MiRNA Metabolic Process	Amyloid-beta Complex Growth Cone Lamellipodium Positive Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Response To Calcium Ion Regulation Of DNA-templated Transcription Amylin Binding Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Toll Signaling Pathway Frizzled Binding Positive Regulation Of DNA-templated Transcription Identical Protein Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Formation Of Structure Involved In A Symbiotic Process Interleukin-5 Receptor Complex Regulation Of Transcription By RNA Polymerase III Positive Regulation Of Semaphorin-plexin Signaling Pathway Positive Regulation Of RNA Metabolic Process Membrane Raft
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