YAF2 and ZFP42

Number of citations of the paper that reports this interaction (PubMedID 21530438)
0

Data Source:
BioGRID (two hybrid)

		YAF2	ZFP42
Description		YY1 associated factor 2	ZFP42 zinc finger protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Chromatin Nucleus Transcription Regulator Complex Cytoplasm PcG Protein Complex
	Molecular Function	DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of DNA-templated Transcription Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription	Regulation Of Transcription By RNA Polymerase II Male Gonad Development Female Gonad Development Meiotic Cell Cycle
Pathways		RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Cortisol levels (saliva) ( 28843169) LDL levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder ( 33824429) Testicular germ cell tumor ( 28604728 28604732) Visceral fat ( 30942860)
Interacting Genes		28 interacting genes: ANP32B CAVIN1 CD300LF DNAAF6 EAF1 GABPB1 IFT57 INO80B LGALS7 LGALS7B MAPRE3 MARK1 MYC MYCN NEDD8 NUTF2 PCDH17 POLR3GL PPP1R11 PTEN SETBP1 SPANXN2 SPANXN3 TLK1 UBC XAGE1B YY1 ZFP42	8 interacting genes: EED LHX2 MEOX2 PIAS2 RNF4 RYBP SUMO1 YAF2
Entrez ID		10138	132625
HPRD ID		09606	15726
Ensembl ID		ENSG00000015153	ENSG00000179059
Uniprot IDs		B4DJQ9 G3V212 Q8IY57	Q96MM3
PDB IDs		2D9G
Enriched GO Terms of Interacting Partners?		Nucleoplasm Regulation Of MiRNA Transcription Positive Regulation Of Telomere Maintenance Protein Tag Activity Regulation Of Synaptic Vesicle Clustering Regulation Of DNA Strand Elongation Ino80 Complex Positive Regulation Of Telomere Maintenance In Response To DNA Damage Chromatin Organization Regulation Of MiRNA Metabolic Process	Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II PML Body Transcription Coregulator Activity Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process DNA Binding Regulation Of Macromolecule Metabolic Process Nucleosome Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Transcription Corepressor Activity Negative Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Protein Sumoylation Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Nucleus Negative Regulation Of Metabolic Process Positive Regulation Of RNA Metabolic Process Roof Of Mouth Development Positive Regulation Of Macromolecule Metabolic Process Nuclear Speck Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Adaxial/abaxial Pattern Formation Positive Regulation Of Metabolic Process Regulation Of Kinetochore Assembly Protein Localization To Nuclear Pore Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Somite Specification SUMO Polymer Binding Negative Regulation Of Action Potential Small Protein Activating Enzyme Binding Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Centromere Complex Assembly Nucleoplasm Negative Regulation Of Protein Localization To Chromatin Microtubule End Regulation Of Ubiquitin-dependent Protein Catabolic Process Chromatin Remodeling Negative Regulation Of Gene Expression, Epigenetic Telencephalon Regionalization
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