YAF2 and CD300LF

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		YAF2	CD300LF
Description		YY1 associated factor 2	CD300 molecule like family member f
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Plasma Membrane Membrane
	Molecular Function	DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding Metal Ion Binding	Phosphatidylserine Binding Transmembrane Signaling Receptor Activity Interleukin-4 Receptor Binding Protein Binding Lipid Binding Identical Protein Binding Ceramide Binding
	Biological Process	Regulation Of DNA-templated Transcription Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription	Immune System Process Immune Response-activating Signaling Pathway Negative Regulation Of Mast Cell Activation Negative Regulation Of MyD88-dependent Toll-like Receptor Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Interleukin-13-mediated Signaling Pathway Positive Regulation Of Interleukin-4-mediated Signaling Pathway Negative Regulation Of Apoptotic Cell Clearance Positive Regulation Of Apoptotic Cell Clearance
Pathways		RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Transcriptional Regulation by E2F6	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Refractive error ( 32231278)	C-reactive protein levels ( 30388399) Coronary artery disease ( 29212778) Fibrinogen ( 23969696 20031577) Fibrinogen levels ( 28107422) Granulocyte count ( 27863252) Lymphocyte count ( 27863252) Monocyte count ( 27863252 32888494) Myeloid white cell count ( 27863252) Neurological blood protein biomarker levels ( 31320639) Neutrophil count ( 27863252) Platelet count ( 32888494) Plateletcrit ( 32888494 27863252) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 27863252 32888494)
Interacting Genes		28 interacting genes: ANP32B CAVIN1 CD300LF DNAAF6 EAF1 GABPB1 IFT57 INO80B LGALS7 LGALS7B MAPRE3 MARK1 MYC MYCN NEDD8 NUTF2 PCDH17 POLR3GL PPP1R11 PTEN SETBP1 SPANXN2 SPANXN3 TLK1 UBC XAGE1B YY1 ZFP42	4 interacting genes: APP INPP5D PTPN6 YAF2
Entrez ID		10138	146722
HPRD ID		09606	17635
Ensembl ID		ENSG00000015153	ENSG00000186074
Uniprot IDs		B4DJQ9 G3V212 Q8IY57	B4DQD2 J3KS52 Q8TDQ1
PDB IDs		2D9G	2NMS
Enriched GO Terms of Interacting Partners?		Nucleoplasm Regulation Of MiRNA Transcription Positive Regulation Of Telomere Maintenance Protein Tag Activity Regulation Of Synaptic Vesicle Clustering Regulation Of DNA Strand Elongation Ino80 Complex Positive Regulation Of Telomere Maintenance In Response To DNA Damage Chromatin Organization Regulation Of MiRNA Metabolic Process	Regulation Of Interleukin-6 Production Positive Regulation Of Cell Activation Immune Effector Process Natural Killer Cell Mediated Immunity Natural Killer Cell Mediated Cytotoxicity Negative Regulation Of Interleukin-6 Production Regulation Of B Cell Differentiation Regulation Of Innate Immune Response Amyloid-beta Complex Innate Immune Response Growth Cone Lamellipodium Myeloid Cell Development Regulation Of Cell Activation Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Negative Regulation Of Leukocyte Proliferation Negative Regulation Of Lymphocyte Proliferation Negative Regulation Of Mononuclear Cell Proliferation Negative Regulation Of Innate Immune Response Leukocyte Mediated Cytotoxicity Epididymis Development SH3 Domain Binding T Cell Receptor Signaling Pathway Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Cell Population Proliferation Defense Response To Symbiont Defense Response To Other Organism Negative Regulation Of Biosynthetic Process Myeloid Leukocyte Activation Regulation Of B Cell Activation Dephosphorylation Lymphocyte Mediated Immunity Acetylcholine Receptor Activator Activity Regulation Of Defense Response Regulation Of Calcium Ion Transmembrane Transport Lipoprotein Particle Regulation Of Cytokine Production Positive Regulation Of Protein Import Leukocyte Mediated Immunity Negative Regulation Of Neutrophil Differentiation Antigen Receptor-mediated Signaling Pathway Negative Regulation Of Macromolecule Metabolic Process Cell Activation Involved In Immune Response PTB Domain Binding Negative Regulation Of Metabolic Process Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Immune Response Regulation Of Tumor Necrosis Factor Production
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