CENPT and DHX29

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CENPT	DHX29
Description		centromere protein T	DExH-box helicase 29
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Inner Kinetochore Nucleus Nucleoplasm Chromosome Cytosol Nuclear Body	Cytoplasm Eukaryotic 43S Preinitiation Complex Cytosolic Small Ribosomal Subunit
	Molecular Function	DNA Binding Protein Binding Protein Heterodimerization Activity	Nucleotide Binding Nucleic Acid Binding RNA Binding RNA Helicase Activity Translation Initiation Factor Activity Helicase Activity ATP Binding Translation Activator Activity Hydrolase Activity Hydrolase Activity, Acting On Acid Anhydrides, In Phosphorus-containing Anhydrides ATP Hydrolysis Activity Ribonucleoside Triphosphate Phosphatase Activity Ribosomal Small Subunit Binding Cadherin Binding
	Biological Process	Mitotic Cell Cycle Chromosome Segregation Chromosome Organization Cell Division Kinetochore Assembly	Formation Of Translation Preinitiation Complex Translation Translational Initiation Ribosome Assembly Positive Regulation Of Translation Positive Regulation Of Translational Initiation
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)	Cocaine dependence ( 31212010)
Interacting Genes		8 interacting genes: APP CENPS COPS5 DHX29 H3C1 PPCDC SNCB TCEA2	3 interacting genes: CENPT PISD TBC1D17
Entrez ID		80152	54505
HPRD ID		07811	10882
Ensembl ID		ENSG00000102901	ENSG00000067248
Uniprot IDs		B3KPB2 Q96BT3	Q7Z478
PDB IDs		7QOO 7R5S 7XHN 7XHO 7YWX
Enriched GO Terms of Interacting Partners?		Transition Metal Ion Binding Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Translation Initiation Factor Activity Phosphopantothenoylcysteine Decarboxylase Activity Phosphopantothenoylcysteine Decarboxylase Complex Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Response To Endoplasmic Reticulum Stress Protein Heterodimerization Activity Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Macrophage Migration Inhibitory Factor Binding Translational Initiation Nitric-oxide Synthase Complex	Phosphatidylserine Decarboxylase Activity Membraneless Organelle Assembly Phosphatidylethanolamine Biosynthetic Process Protein Autoprocessing Lipid Droplet Formation Mitochondrial Protein Catabolic Process Carboxy-lyase Activity Kinetochore Organization Kinetochore Assembly Inner Kinetochore Phosphatidylethanolamine Metabolic Process Organelle Assembly
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