TAX1BP3 and GLS

Number of citations of the paper that reports this interaction (PubMedID 11163757)
0

Data Source:
HPRD (two hybrid, in vitro)

		TAX1BP3	GLS
Description		Tax1 binding protein 3	glutaminase
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GO Annotations	Cellular Component	Fibrillar Center Nucleus Cytoplasm Cytosol Plasma Membrane Actin Cytoskeleton Membrane Extracellular Exosome	Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Synapse
	Molecular Function	Protein Binding Beta-catenin Binding	Glutaminase Activity Protein Binding Hydrolase Activity
	Biological Process	Rho Protein Signal Transduction Negative Regulation Of Cell Population Proliferation Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Regulation Of Cdc42 Protein Signal Transduction Negative Regulation Of Protein Localization To Cell Surface	Suckling Behavior Regulation Of Respiratory Gaseous Exchange By Nervous System Process Amino Acid Metabolic Process Glutamate Biosynthetic Process Glutamine Metabolic Process L-glutamine Catabolic Process Chemical Synaptic Transmission Protein Homotetramerization Intracellular Glutamate Homeostasis
Pathways		RHO GTPases Activate Rhotekin and Rhophilins	Glutamate Neurotransmitter Release Cycle TP53 Regulates Metabolic Genes Glutamate and glutamine metabolism
Drugs			Glutamic acid
Diseases
GWAS			Appendicular lean mass ( 33097823) Chronotype ( 30696823) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 27863252 32888494) JT interval (sulfonylurea treatment interaction) ( 27958378) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		14 interacting genes: ARHGEF16 ARNT2 CDK5RAP3 CTNNB1 DTX1 GATA1 GLS GLS2 PLK4 RNF183 RTKN STAU1 TCEA2 TRIM29	7 interacting genes: ATXN10 CDC42 OGT PARD6A RSPH1 SNTA1 TAX1BP3
Entrez ID		30851	2744
HPRD ID		18160	00700
Ensembl ID		ENSG00000213977	ENSG00000115419
Uniprot IDs		A0A087X282 O14907	H7C201 O94925
PDB IDs		2KG2 2L4S 2L4T 2VZ5 3GJ9 3SFJ 4E3B 4NNL 4NNM	3CZD 3UNW 3UO9 3VOY 3VOZ 3VP0 3VP1 3VP2 3VP3 3VP4 4O7D 5D3O 5FI2 5FI6 5FI7 5HL1 5I94 5JYO 5JYP 5U0I 5U0J 5UQE 5WJ6 6LOX 6UJG 6UJM 6UK6 6UKB 6UL9 6ULA 6ULJ 6UMC 6UMD 6UME 6UMF 7REN 7RGG 7SBM 7SBN 8BSK 8BSL 8BSM 8BSN 8GWR 8IMA 8IMB 8JUB 8JUE 8SZJ
Enriched GO Terms of Interacting Partners?		L-glutamine Catabolic Process Glutaminase Activity Glutamate Biosynthetic Process Glutamine Metabolic Process Transcription Regulator Complex DNA-templated Transcription Mesenchymal Stem Cell Differentiation Positive Regulation Of Determination Of Dorsal Identity Negative Regulation Of Mitotic Cell Cycle, Embryonic Centrosome Beta-catenin-ICAT Complex Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Glial Cell Fate Determination Protein-DNA Complex Renal Inner Medulla Development In Utero Embryonic Development Scrib-APC-beta-catenin Complex Regulation Of Apoptotic Process Embryo Development Ending In Birth Or Egg Hatching Multicellular Organism Development Renal Outer Medulla Development Transcription Coregulator Binding Renal Vesicle Formation Canonical Wnt Signaling Pathway Involved In Mesenchymal Stem Cell Differentiation Myeloid Cell Differentiation Chordate Embryonic Development Positive Regulation Of Branching Involved In Lung Morphogenesis Neural Plate Development Regulation Of Glycoprotein Biosynthetic Process Regulation Of Programmed Cell Death Transcription By RNA Polymerase II Basophil Differentiation P53 Binding Eosinophil Fate Commitment Regulation Of Primitive Erythrocyte Differentiation Erythrocyte Differentiation Glutamate Metabolic Process Amino Acid Biosynthetic Process Glutamine Family Amino Acid Metabolic Process Septin Ring Organization Oviduct Development Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Mononuclear Cell Differentiation Protein Modification By Small Protein Conjugation Fungiform Papilla Formation Beta-catenin-TCF7L2 Complex Astrocyte-dopaminergic Neuron Signaling Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Regulation Of Centriole-centriole Cohesion Embryonic Skeletal Limb Joint Morphogenesis	Cell Projection Cytoskeleton GTP-dependent Protein Binding Wnt Signaling Pathway Establishment Or Maintenance Of Apical/basal Cell Polarity Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Cell Projection Assembly Plasma Membrane Bounded Cell Projection Assembly Plasma Membrane Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Regulation Of Cytokinesis Cytoplasm GBD Domain Binding Storage Vacuole Endothelin Receptor Signaling Pathway Involved In Heart Process Protein O-acetylglucosaminyltransferase Activity Protein Transport From Ciliary Membrane To Plasma Membrane Axoneme Radial Spoke Head 1 Radial Spoke Head 3 Cell-cell Junction Organization Organelle Organization Positive Regulation Of Pinocytosis Apolipoprotein A-I Receptor Binding G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Regulation Of Cell Division Midbody Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis Neuropilin Signaling Pathway Negative Regulation Of Protein-containing Complex Assembly Cellular Component Assembly Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Establishment Or Maintenance Of Cell Polarity Cytosol Syntrophin Complex Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Cilium Positive Regulation Of Protein Localization To Centrosome PAR Polarity Complex Outer Dense Fiber Radial Spoke Head Organelle Assembly Establishment Of Golgi Localization Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Protein-containing Complex
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