TARBP2 and HDHD2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		TARBP2	HDHD2
Gene Name		TAR (HIV-1) RNA binding protein 2	haloacid dehalogenase-like hydrolase domain containing 2
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol RISC Complex Micro-ribonucleoprotein Complex Perinuclear Region Of Cytoplasm	Extracellular Vesicular Exosome
	Molecular Function	Double-stranded RNA Binding Protein Binding SiRNA Binding MiRNA Binding Protein Homodimerization Activity	Enzyme Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Translation Negative Regulation Of Protein Kinase Activity Gene Expression Production Of SiRNA Involved In RNA Interference Targeting Of MRNA For Destruction Involved In RNA Interference Pre-miRNA Processing MiRNA Loading Onto RISC Involved In Gene Silencing By MiRNA Positive Regulation Of Viral Genome Replication Regulation Of Viral Transcription Negative Regulation Of Defense Response To Virus By Host	Biological_process
Pathways		Regulatory RNA pathways MicroRNA (miRNA) biogenesis Small interfering RNA (siRNA) biogenesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		21 interactors: AGO2 APP DICER1 EIF2AK2 HDHD2 IKBKG KCNIP3 MED21 NEDD4L NEUROG1 NF2 NUDT18 PRKRA RBM14 STRBP TCEANC TGIF2 TOP1 TRAF4 VAV2 ZNF346	12 interactors: BAI2 CFD CRMP1 DVL1 EPHB6 LUC7L2 MEOX2 MGST2 PIP5K1C SOD2 TARBP2 TRAPPC11
Entrez ID		6895	84064
HPRD ID		05446	13640
Ensembl ID		ENSG00000139546	ENSG00000167220
Uniprot IDs		Q15633	Q9H0R4
PDB IDs		2CPN 3ADL 3LLH	3HLT
Enriched GO Terms of Interacting Partners?		Regulation Of Gene Expression RNA Interference Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of NIK/NF-kappaB Signaling Posttranscriptional Regulation Of Gene Expression Regulation Of NIK/NF-kappaB Signaling Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Cellular Response To DsRNA Posttranscriptional Gene Silencing Positive Regulation Of Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Programmed Cell Death Regulation Of Apoptotic Process Cell Death Death Gene Silencing By RNA Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Death Response To DsRNA Production Of SiRNA Involved In RNA Interference Regulation Of Kinase Activity Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Response To Virus Cellular Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Pre-miRNA Processing Macromolecule Biosynthetic Process Negative Regulation Of Gene Expression Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process Gene Silencing Sensory Organ Development Apoptotic Process Activation Of NF-kappaB-inducing Kinase Activity Production Of MiRNAs Involved In Gene Silencing By MiRNA Multicellular Organismal Development Positive Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Regulation Of Cell Differentiation Response To Stress	Axon Guidance Neuron Development Axonogenesis Response To External Stimulus Axon Development Neuron Differentiation Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Nervous System Development Erythrophore Differentiation Age-dependent Response To Reactive Oxygen Species Vasodilation By Acetylcholine Involved In Regulation Of Systemic Arterial Blood Pressure Neuron Projection Development Glutathione Metabolic Process Cell Projection Morphogenesis Generation Of Neurons Cell Part Morphogenesis Neurogenesis MiRNA Loading Onto RISC Involved In Gene Silencing By MiRNA Cell Development Neurotransmitter Secretion Cell Morphogenesis Convergent Extension Involved In Neural Plate Elongation Targeting Of MRNA For Destruction Involved In RNA Interference Response To Silicon Dioxide Response To Magnetism System Development Secretion By Cell Cell Projection Organization Regulation Of Neurotransmitter Levels Collateral Sprouting Age-dependent Response To Oxidative Stress Production Of SiRNA Involved In RNA Interference Detection Of Oxygen Peptide Metabolic Process Locomotion Convergent Extension Involved In Organogenesis Somite Specification Response To Selenium Ion Ribonucleoprotein Complex Assembly Neurotransmitter Transport Secretion Multicellular Organismal Development Oxygen Homeostasis Pyrimidine Nucleobase Catabolic Process Protein Localization To Microtubule Platelet Activation RNA Interference
Tagcloud ?		computational conducting defining deregulated destabilization destabilizes destabilizing displaying elements govern governed huntington integrating isogenic metastatic modulators overrepresented represses searches srse srses tbses termed transcriptionally transcripts unbiased uncovered unexplored znf395
Tagcloud (Difference) ?		computational conducting defining deregulated destabilization destabilizes destabilizing displaying elements govern governed huntington integrating isogenic metastatic modulators overrepresented represses searches srse srses tbses termed transcriptionally transcripts unbiased uncovered unexplored znf395
Tagcloud (Intersection) ?