TARBP2 and RBM14

Number of citations of the paper that reports this interaction (PMID 11443112)
35

Data Source:
HPRD (in vitro)

		TARBP2	RBM14
Gene Name		TAR (HIV-1) RNA binding protein 2	RNA binding motif protein 14
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol RISC Complex Micro-ribonucleoprotein Complex Perinuclear Region Of Cytoplasm	Nucleoplasm Transcription Factor Complex Nucleolus Mediator Complex Ribonucleoprotein Complex
	Molecular Function	Double-stranded RNA Binding Protein Binding SiRNA Binding MiRNA Binding Protein Homodimerization Activity	Nucleotide Binding RNA Polymerase II Transcription Cofactor Activity RNA Binding Protein Binding Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Protein Binding, Bridging Poly(A) RNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Translation Negative Regulation Of Protein Kinase Activity Gene Expression Production Of SiRNA Involved In RNA Interference Targeting Of MRNA For Destruction Involved In RNA Interference Pre-miRNA Processing MiRNA Loading Onto RISC Involved In Gene Silencing By MiRNA Positive Regulation Of Viral Genome Replication Regulation Of Viral Transcription Negative Regulation Of Defense Response To Virus By Host	DNA Replication DNA Repair DNA Recombination Transcription From RNA Polymerase II Promoter Response To Hormone Histone Deacetylation Intracellular Estrogen Receptor Signaling Pathway Glucocorticoid Receptor Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Regulatory RNA pathways MicroRNA (miRNA) biogenesis Small interfering RNA (siRNA) biogenesis
Drugs
Diseases
GWAS			Bipolar disorder ( 21926972)
Protein-Protein Interactions		21 interactors: AGO2 APP DICER1 EIF2AK2 HDHD2 IKBKG KCNIP3 MED21 NEDD4L NEUROG1 NF2 NUDT18 PRKRA RBM14 STRBP TCEANC TGIF2 TOP1 TRAF4 VAV2 ZNF346	11 interactors: EP300 NCOA6 NR3C1 PARP1 QKI RUNX1 RUNX2 SS18 SYT1 TARBP2 XRCC5
Entrez ID		6895	10432
HPRD ID		05446	11485
Ensembl ID		ENSG00000139546
Uniprot IDs		Q15633	Q96PK6
PDB IDs		2CPN 3ADL 3LLH	2DNP
Enriched GO Terms of Interacting Partners?		Regulation Of Gene Expression RNA Interference Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of NIK/NF-kappaB Signaling Posttranscriptional Regulation Of Gene Expression Regulation Of NIK/NF-kappaB Signaling Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Cellular Response To DsRNA Posttranscriptional Gene Silencing Positive Regulation Of Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Programmed Cell Death Regulation Of Apoptotic Process Cell Death Death Gene Silencing By RNA Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Death Response To DsRNA Production Of SiRNA Involved In RNA Interference Regulation Of Kinase Activity Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Response To Virus Cellular Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Pre-miRNA Processing Macromolecule Biosynthetic Process Negative Regulation Of Gene Expression Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process Gene Silencing Sensory Organ Development Apoptotic Process Activation Of NF-kappaB-inducing Kinase Activity Production Of MiRNAs Involved In Gene Silencing By MiRNA Multicellular Organismal Development Positive Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Regulation Of Cell Differentiation Response To Stress	RNA Metabolic Process Positive Regulation Of Gene Expression Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Transcription, DNA-templated Heterocycle Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Response To Organic Substance DNA-templated Transcription, Initiation Glucocorticoid Receptor Signaling Pathway Nitrogen Compound Metabolic Process Cellular Response To Organic Substance Hemopoiesis Regulation Of Transcription, DNA-templated Immune System Development Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Biosynthetic Process Anatomical Structure Development Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Developmental Process Regulation Of Metabolic Process System Development Organ Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Immune System Process Myeloid Cell Differentiation Negative Regulation Of Gene Expression Response To Stimulus Multicellular Organismal Development Cell Differentiation Cellular Response To Stimulus Chordate Embryonic Development Anatomical Structure Morphogenesis Stem Cell Differentiation
Tagcloud ?		computational conducting defining deregulated destabilization destabilizes destabilizing displaying elements govern governed huntington integrating isogenic metastatic modulators overrepresented represses searches srse srses tbses termed transcriptionally transcripts unbiased uncovered unexplored znf395	aggregating conjugation detergent dialkylated eif4a1 g3bp glycine granular hek hnrnps identities immunocytochemistry insoluble isotope nono oligomerization pabpc1 paraspeckle proteinopathies psf ptm quantitate rgg rrm s6 silac tdp tls ubiquitination
Tagcloud (Difference) ?		computational conducting defining deregulated destabilization destabilizes destabilizing displaying elements govern governed huntington integrating isogenic metastatic modulators overrepresented represses searches srse srses tbses termed transcriptionally transcripts unbiased uncovered unexplored znf395	aggregating conjugation detergent dialkylated eif4a1 g3bp glycine granular hek hnrnps identities immunocytochemistry insoluble isotope nono oligomerization pabpc1 paraspeckle proteinopathies psf ptm quantitate rgg rrm s6 silac tdp tls ubiquitination
Tagcloud (Intersection) ?