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HDHD2 and EPHB6
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
HPRD
(two hybrid)
HDHD2
EPHB6
Gene Name
haloacid dehalogenase-like hydrolase domain containing 2
EPH receptor B6
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Vesicular Exosome
Extracellular Region
Cytosol
Plasma Membrane
Integral Component Of Plasma Membrane
Molecular Function
Enzyme Binding
Metal Ion Binding
Receptor Activity
Ephrin Receptor Activity
ATP Binding
Biological Process
Biological_process
Protein Phosphorylation
Axon Guidance
Ephrin Receptor Signaling Pathway
Pathways
EPHB-mediated forward signaling
Ephrin signaling
EPH-ephrin mediated repulsion of cells
Axon guidance
EPH-Ephrin signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions
12 interactors:
BAI2
CFD
CRMP1
DVL1
EPHB6
LUC7L2
MEOX2
MGST2
PIP5K1C
SOD2
TARBP2
TRAPPC11
15 interactors:
CBL
CRK
CRKL
EFNB2
EPHB1
GRB2
HDHD2
INCA1
MLLT4
NIF3L1
NOTCH2NL
REL
SAT1
TCF4
TRIM39
Entrez ID
84064
2051
HPRD ID
13640
04133
Ensembl ID
ENSG00000167220
ENSG00000106123
Uniprot IDs
Q9H0R4
O15197
PDB IDs
3HLT
Enriched GO Terms of Interacting Partners
?
Axon Guidance
Neuron Development
Axonogenesis
Response To External Stimulus
Axon Development
Neuron Differentiation
Cell Morphogenesis Involved In Neuron Differentiation
Chemotaxis
Neuron Projection Morphogenesis
Cell Morphogenesis Involved In Differentiation
Nervous System Development
Erythrophore Differentiation
Age-dependent Response To Reactive Oxygen Species
Vasodilation By Acetylcholine Involved In Regulation Of Systemic Arterial Blood Pressure
Neuron Projection Development
Glutathione Metabolic Process
Cell Projection Morphogenesis
Generation Of Neurons
Cell Part Morphogenesis
Neurogenesis
MiRNA Loading Onto RISC Involved In Gene Silencing By MiRNA
Cell Development
Neurotransmitter Secretion
Cell Morphogenesis
Convergent Extension Involved In Neural Plate Elongation
Targeting Of MRNA For Destruction Involved In RNA Interference
Response To Silicon Dioxide
Response To Magnetism
System Development
Secretion By Cell
Cell Projection Organization
Regulation Of Neurotransmitter Levels
Collateral Sprouting
Age-dependent Response To Oxidative Stress
Production Of SiRNA Involved In RNA Interference
Detection Of Oxygen
Peptide Metabolic Process
Locomotion
Convergent Extension Involved In Organogenesis
Somite Specification
Response To Selenium Ion
Ribonucleoprotein Complex Assembly
Neurotransmitter Transport
Secretion
Multicellular Organismal Development
Oxygen Homeostasis
Pyrimidine Nucleobase Catabolic Process
Protein Localization To Microtubule
Platelet Activation
RNA Interference
Positive Regulation Of Signal Transduction
Regulation Of Signal Transduction
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Signaling
Regulation Of Intracellular Signal Transduction
Enzyme Linked Receptor Protein Signaling Pathway
Blood Vessel Development
Vasculature Development
Ephrin Receptor Signaling Pathway
Signaling
Cell Communication
Positive Regulation Of Intracellular Signal Transduction
Cardiovascular System Development
Regulation Of Cell Death
Cell Surface Receptor Signaling Pathway
Signal Transduction
Neurotrophin TRK Receptor Signaling Pathway
Cellular Response To Stimulus
Neurotrophin Signaling Pathway
Cellular Response To Growth Factor Stimulus
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of ERBB Signaling Pathway
Response To Growth Factor
Regulation Of MAPK Cascade
Regulation Of Cellular Process
Activation Of MAPKK Activity
Regulation Of Phosphorylation
Regulation Of Metabolic Process
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Angiogenesis
Regulation Of ERBB Signaling Pathway
Spermidine Acetylation
Catenin Import Into Nucleus
7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Regulation Of Protein Metabolic Process
Regulation Of Phosphorus Metabolic Process
Axon Guidance
Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process
Dihydrobiopterin Metabolic Process
Putrescine Catabolic Process
Cell-cell Signaling
Blood Vessel Morphogenesis
Response To Stimulus
Anatomical Structure Morphogenesis
Maintenance Of DNA Repeat Elements
Positive Regulation Of Metabolic Process
Organ Morphogenesis
Response To Organic Substance
Oxalate Transport
Tagcloud
?
abca1
adamtsl3
aiming
apc
crc
elac1
epha3
ercc6
excluding
exome
fbxw7
germline
kbiosciences
marginal
mll3
obscn
pkhd1
recessive
rs4987622
rs6464211
rs6947538
silico
smad4
snps
somatic
spite
strongest
syne1
trpv6
Tagcloud (Difference)
?
abca1
adamtsl3
aiming
apc
crc
elac1
epha3
ercc6
excluding
exome
fbxw7
germline
kbiosciences
marginal
mll3
obscn
pkhd1
recessive
rs4987622
rs6464211
rs6947538
silico
smad4
snps
somatic
spite
strongest
syne1
trpv6
Tagcloud (Intersection)
?