TAL2 and CBFA2T2

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		TAL2	CBFA2T2
Gene Name		T-cell acute lymphocytic leukemia 2	core-binding factor, runt domain, alpha subunit 2; translocated to, 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus
	Molecular Function	DNA Binding Protein Dimerization Activity	Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Post-embryonic Development Thalamus Development Midbrain Development Multicellular Organism Growth	Positive Regulation Of Neuron Projection Development Negative Regulation Of Neuron Projection Development Epithelial Cell Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS		Cognitive performance ( 20125193) Menarche (age at onset) ( 19448620) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Protein-Protein Interactions		9 interactors: CBFA2T2 LMO1 LMO2 MAPK3 PCBD2 RUNX1T1 TCF12 TCF3 TCF4	23 interactors: APP ATN1 ATXN1L CBFA2T3 CBFB FBXL19 GTF2E1 ID3 LBP MDFI NCOR1 NCOR2 NEUROG1 NOTCH3 PDP1 PRDM14 RERE RUNX1 SIN3A TAL2 TCP1 WDYHV1 ZNF652
Entrez ID		6887	9139
HPRD ID		01735	04721
Ensembl ID		ENSG00000186051	ENSG00000078699
Uniprot IDs		Q16559	O43439
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Neuron Differentiation Positive Regulation Of Neurogenesis Positive Regulation Of Cell Development Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Neuron Differentiation Regulation Of Metabolic Process Transcription, DNA-templated Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process RNA Biosynthetic Process Regulation Of Neurogenesis Regulation Of Binding Negative Regulation Of Cell Differentiation Generation Of Neurons Regulation Of Cell Differentiation Neurogenesis Regulation Of Cell Development Positive Regulation Of Cell Differentiation Transcription From RNA Polymerase II Promoter Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Somatic Stem Cell Maintenance Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process RNA Metabolic Process Negative Regulation Of Apolipoprotein Binding Cellular Nitrogen Compound Metabolic Process Cell Differentiation Negative Regulation Of Cellular Metabolic Process Gene Expression Canonical Wnt Signaling Pathway Cellular Macromolecule Biosynthetic Process Muscle Structure Development Nervous System Development	Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Metabolic Process Multicellular Organismal Development Nitrogen Compound Metabolic Process Biosynthetic Process Organ Development Definitive Hemopoiesis Central Nervous System Development Developmental Process System Development Anatomical Structure Development Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Notch Signaling Pathway Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Cell Differentiation Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process Regulation Of Cellular Process Negative Regulation Of Cell Differentiation Forebrain Development DNA-templated Transcription, Initiation Metabolic Process Embryo Development Negative Regulation Of Cellular Metabolic Process Myeloid Cell Differentiation Thalamus Development In Utero Embryonic Development Nervous System Development Positive Regulation Of Mitotic Cell Cycle
Tagcloud ?		arose carcinomas cooperation cosegregated dimer e2 e6 e7 exist existed hox implying involving lacked lymphoblastic lymphomagenic lymphomas myc notion oncogenes oncogenic pim proto rb rbtn1 repeat supporting transgenic ttg1
Tagcloud (Difference) ?		arose carcinomas cooperation cosegregated dimer e2 e6 e7 exist existed hox implying involving lacked lymphoblastic lymphomagenic lymphomas myc notion oncogenes oncogenic pim proto rb rbtn1 repeat supporting transgenic ttg1
Tagcloud (Intersection) ?