TAL2 and PCBD2

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		TAL2	PCBD2
Gene Name		T-cell acute lymphocytic leukemia 2	pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Cellular_component Nucleus Mitochondrion
	Molecular Function	DNA Binding Protein Dimerization Activity	Phenylalanine 4-monooxygenase Activity Protein Binding 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Post-embryonic Development Thalamus Development Midbrain Development Multicellular Organism Growth	Tetrahydrobiopterin Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Protein Homotetramerization Protein Heterooligomerization Oxidation-reduction Process
Pathways
Drugs
Diseases
GWAS		Cognitive performance ( 20125193) Menarche (age at onset) ( 19448620) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)	Bulimia nervosa ( 23568457) Colorectal cancer ( 23263487) Height ( 18391951)
Protein-Protein Interactions		9 interactors: CBFA2T2 LMO1 LMO2 MAPK3 PCBD2 RUNX1T1 TCF12 TCF3 TCF4	31 interactors: AATF APP ASCC2 BRF1 C1D CDC5L CENPK CHAF1A GTF2E1 HES4 IRF2BP1 KCNIP3 MAGEA11 MED21 MED30 MED4 MED7 MET PBXIP1 PCBD1 PHF14 PML RUNX1T1 SNW1 SSX3 SSX5 STAT3 TAL2 TGIF2LY XBP1 ZZZ3
Entrez ID		6887	84105
HPRD ID		01735	17824
Ensembl ID		ENSG00000186051
Uniprot IDs		Q16559	Q9H0N5
PDB IDs			4C45
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Neuron Differentiation Positive Regulation Of Neurogenesis Positive Regulation Of Cell Development Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Neuron Differentiation Regulation Of Metabolic Process Transcription, DNA-templated Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process RNA Biosynthetic Process Regulation Of Neurogenesis Regulation Of Binding Negative Regulation Of Cell Differentiation Generation Of Neurons Regulation Of Cell Differentiation Neurogenesis Regulation Of Cell Development Positive Regulation Of Cell Differentiation Transcription From RNA Polymerase II Promoter Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Somatic Stem Cell Maintenance Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process RNA Metabolic Process Negative Regulation Of Apolipoprotein Binding Cellular Nitrogen Compound Metabolic Process Cell Differentiation Negative Regulation Of Cellular Metabolic Process Gene Expression Canonical Wnt Signaling Pathway Cellular Macromolecule Biosynthetic Process Muscle Structure Development Nervous System Development	Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process RNA Biosynthetic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Cellular Process Regulation Of Transcription From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway DNA-templated Transcription, Initiation Positive Regulation Of Transcription, DNA-templated Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Apoptotic Process Negative Regulation Of Gene Expression Programmed Cell Death Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Cell Death Death Stem Cell Maintenance Transcription From RNA Polymerase II Promoter Cell Differentiation Positive Regulation Of Histone Modification Negative Regulation Of Cell Differentiation Stem Cell Development Developmental Process Positive Regulation Of Metabolic Process Regulation Of Cell Differentiation
Tagcloud ?		arose carcinomas cooperation cosegregated dimer e2 e6 e7 exist existed hox implying involving lacked lymphoblastic lymphomagenic lymphomas myc notion oncogenes oncogenic pim proto rb rbtn1 repeat supporting transgenic ttg1
Tagcloud (Difference) ?		arose carcinomas cooperation cosegregated dimer e2 e6 e7 exist existed hox implying involving lacked lymphoblastic lymphomagenic lymphomas myc notion oncogenes oncogenic pim proto rb rbtn1 repeat supporting transgenic ttg1
Tagcloud (Intersection) ?