TAL2 and LMO1

Number of citations of the paper that reports this interaction (PMID 7957052)
57

Data Source:
BioGRID (two hybrid)
HPRD (in vivo)

		TAL2	LMO1
Gene Name		T-cell acute lymphocytic leukemia 2	LIM domain only 1 (rhombotin 1)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus
	Molecular Function	DNA Binding Protein Dimerization Activity	Zinc Ion Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Post-embryonic Development Thalamus Development Midbrain Development Multicellular Organism Growth	Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS		Cognitive performance ( 20125193) Menarche (age at onset) ( 19448620) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)	Alcohol consumption ( 23743675) Fasting glucose-related traits (interaction with BMI) ( 22581228) Neuroblastoma ( 22941191 21124317)
Protein-Protein Interactions		9 interactors: CBFA2T2 LMO1 LMO2 MAPK3 PCBD2 RUNX1T1 TCF12 TCF3 TCF4	38 interactors: ADAMTSL4 AES BCL11A BLZF1 CARD9 CDCA7L CDX4 CEP170P1 CEP44 ERBB2IP FAM154A FAM208B GABPB1 GATA3 GOLGA2 IKZF3 KANK2 KRT40 LDB1 LPXN LYL1 LZTS2 NHLH1 NUTM1 PHC2 PTPN3 RBBP8 REL SNTA1 SOX5 SPERT TAL1 TAL2 TCF4 TFIP11 TRIM27 ZBTB43 ZNF219
Entrez ID		6887	4004
HPRD ID		01735	01738
Ensembl ID		ENSG00000186051	ENSG00000166407
Uniprot IDs		Q16559	P25800
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Neuron Differentiation Positive Regulation Of Neurogenesis Positive Regulation Of Cell Development Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Neuron Differentiation Regulation Of Metabolic Process Transcription, DNA-templated Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process RNA Biosynthetic Process Regulation Of Neurogenesis Regulation Of Binding Negative Regulation Of Cell Differentiation Generation Of Neurons Regulation Of Cell Differentiation Neurogenesis Regulation Of Cell Development Positive Regulation Of Cell Differentiation Transcription From RNA Polymerase II Promoter Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Somatic Stem Cell Maintenance Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process RNA Metabolic Process Negative Regulation Of Apolipoprotein Binding Cellular Nitrogen Compound Metabolic Process Cell Differentiation Negative Regulation Of Cellular Metabolic Process Gene Expression Canonical Wnt Signaling Pathway Cellular Macromolecule Biosynthetic Process Muscle Structure Development Nervous System Development	Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Negative Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Cellular Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Wnt Signaling Pathway Organ Development Positive Regulation Of Cellular Metabolic Process Interferon-gamma Secretion Multicellular Organismal Development Cellular Metabolic Process Anatomical Structure Development Developmental Process System Development Interferon-gamma Production Negative Regulation Of Interleukin-2 Production Regulation Of Binding Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Cytokine Biosynthetic Process Definitive Hemopoiesis Embryo Development
Tagcloud ?		arose carcinomas cooperation cosegregated dimer e2 e6 e7 exist existed hox implying involving lacked lymphoblastic lymphomagenic lymphomas myc notion oncogenes oncogenic pim proto rb rbtn1 repeat supporting transgenic ttg1	bhlh collaborates collaboration construct demonstrating dispensable dysregulation elements exerts helix inappropriately interfere interstitial juxtaposed lastly lymphoblastic mesoderm misexpressed oncogenesis product recapitulating scl sil situation supporting tcl5 transactivation translocations whereby
Tagcloud (Difference) ?		arose carcinomas cooperation cosegregated dimer e2 e6 e7 exist existed hox implying involving lacked lymphomagenic lymphomas myc notion oncogenes oncogenic pim proto rb rbtn1 repeat transgenic ttg1	bhlh collaborates collaboration construct demonstrating dispensable dysregulation elements exerts helix inappropriately interfere interstitial juxtaposed lastly mesoderm misexpressed oncogenesis product recapitulating scl sil situation tcl5 transactivation translocations whereby
Tagcloud (Intersection) ?		lymphoblastic supporting