TAF11 and NFYC

Number of citations of the paper that reports this interaction (PMID 11689552)
18

Data Source:
BioGRID (pull down)

		TAF11	NFYC
Gene Name		TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa	nuclear transcription factor Y, gamma
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Gene Ontology Annotations	Cellular Component	Nucleoplasm Transcription Factor TFIID Complex Golgi Apparatus	Nucleus Nucleoplasm CCAAT-binding Factor Complex Protein-DNA Complex
	Molecular Function	DNA Binding Transcription Coactivator Activity Protein Binding Vitamin D Receptor Binding Thyroid Hormone Receptor Binding Protein Heterodimerization Activity Protein N-terminus Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Transcription Factor Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity
	Biological Process	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process Positive Regulation By Host Of Viral Transcription	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Protein Folding Cellular Lipid Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Transcription, DNA-templated
Pathways		RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome	PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins ATF4 activates genes ATF6-alpha activates chaperone genes Regulation of cholesterol biosynthesis by SREBP (SREBF) Activation of gene expression by SREBF (SREBP) Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) PERK regulates gene expression ATF6-alpha activates chaperones Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS			Platelet counts ( 21507922)
Protein-Protein Interactions		28 interactors: APP APPBP2 CPSF1 GTF2B GTF2E1 GTF2F1 HIST3H3 LZTR1 NFYA NFYB NFYC RELA RXRA RXRB TAF1 TAF10 TAF12 TAF13 TAF2 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9 TBP TRIM24 VDR	27 interactors: ADNP2 ARID2 ATF6 ATF6B CIC CSN2 DR1 DST GAPDH GLTSCR1 GLTSCR1L KIAA2018 LMO4 MYC NFYA NFYB POGZ SMAD2 SMAD3 SNX2 SP1 SREBF2 TAF11 TAF12 TAF6 TBP ZDHHC17
Entrez ID		6882	4802
HPRD ID		15980	05633
Ensembl ID		ENSG00000064995	ENSG00000066136
Uniprot IDs		Q15544	Q13952
PDB IDs		1BH8 1BH9	1N1J 4AWL
Enriched GO Terms of Interacting Partners?		Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Transcription Elongation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Viral Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Metabolic Process Peptidyl-lysine Modification Regulation Of Cellular Process Maternal Placenta Development Histone H3 Acetylation Cellular Response To Steroid Hormone Stimulus Histone Modification Cellular Response To Organic Cyclic Compound Maternal Process Involved In Female Pregnancy Cellular Response To Lipid	Transcription, DNA-templated RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process RNA Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Gene Expression Biosynthetic Process Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Regulation Of Metabolic Process DNA-templated Transcription, Elongation Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of RNA Biosynthetic Process Primary MiRNA Processing Viral Process Regulation Of Nodal Signaling Pathway Cellular Metabolic Process SMAD Protein Complex Assembly Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Paraxial Mesoderm Morphogenesis Positive Regulation By Host Of Viral Transcription Positive Regulation Of Metabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Tagcloud ?		autosomal copy ct47 d4z4 dystrophy euchromatic extreme facioscapulohumeral governed h3k27me3 h3k9me3 heterochromatic heterochromatinization hypermethylation leaky lymphoblastoid macrosatellite msrs muscular organized originating prr20 repressive testis trimethylated trimethylation understudied xq24 zav	associates attempt blastocyst cdc25a cdc42 egg embryonal esg1 exist forced icm immediately immunoprecipitated inner kh notion nr5a2 oct3 overlap pluripotency polar pou5f1 preimplantation supporting te transcript transcriptase transcripts trophectoderm
Tagcloud (Difference) ?		autosomal copy ct47 d4z4 dystrophy euchromatic extreme facioscapulohumeral governed h3k27me3 h3k9me3 heterochromatic heterochromatinization hypermethylation leaky lymphoblastoid macrosatellite msrs muscular organized originating prr20 repressive testis trimethylated trimethylation understudied xq24 zav	associates attempt blastocyst cdc25a cdc42 egg embryonal esg1 exist forced icm immediately immunoprecipitated inner kh notion nr5a2 oct3 overlap pluripotency polar pou5f1 preimplantation supporting te transcript transcriptase transcripts trophectoderm
Tagcloud (Intersection) ?