TAF11 and GTF2F1

Number of citations of the paper that reports this interaction (PubMedID 9159119)
32

Data Source:
BioGRID (biochemical, pull down)

		TAF11	GTF2F1
Description		TATA-box binding protein associated factor 11	general transcription factor IIF subunit 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor TFIID Complex Golgi Apparatus	Nucleus Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFIIF Complex Cell Junction Protein-containing Complex
	Molecular Function	Transcription Coactivator Activity Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity TBP-class Protein Binding Nuclear Vitamin D Receptor Binding Nuclear Thyroid Hormone Receptor Binding Protein Heterodimerization Activity	RNA Polymerase II General Transcription Initiation Factor Binding TFIIF-class Transcription Factor Complex Binding DNA Binding RNA Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Phosphatase Activator Activity Protein Phosphatase Binding Protein Domain Specific Binding Promoter-specific Chromatin Binding
	Biological Process	Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter MRNA Transcription By RNA Polymerase II Host-mediated Activation Of Viral Transcription RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II	Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter Transcription Elongation By RNA Polymerase II Response To Virus Negative Regulation Of Protein Binding Positive Regulation Of Transcription Elongation By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance	Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex RNA Pol II CTD phosphorylation and interaction with CE during HIV infection HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation Viral Messenger RNA Synthesis RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes FGFR2 alternative splicing RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes mRNA Capping mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Elongation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Pol II CTD phosphorylation and interaction with CE Signaling by FGFR2 IIIa TM Estrogen-dependent gene expression
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 34021172) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		28 interacting genes: APP APPBP2 CPSF1 GTF2B GTF2E1 GTF2F1 H3-4 LZTR1 NFYA NFYB NFYC RELA RXRA RXRB TAF1 TAF10 TAF12 TAF13 TAF2 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9 TBP TRIM24 VDR	34 interacting genes: ABL1 AHR AR ARNT ATF7IP BCL2L13 CCNT1 CDK9 CEBPA CFTR CSNK2A1 CTDP1 CTDSP1 DAPK1 FEZ1 FNDC3B FOS GTF2A1 GTF2B GTF2E1 GTF2E2 GTF2F2 GTF2H4 JUN MAGEC1 MSX2 MYC PARP1 PSMC2 PTN SRF TAF1 TAF11 TRIM27
Entrez ID		6882	2962
HPRD ID		15980	01803
Ensembl ID		ENSG00000064995	ENSG00000125651
Uniprot IDs		Q15544	P35269
PDB IDs		1BH8 1BH9 6MZD 6MZL 7EDX 7EG7 7EG8 7EG9 7EGA 7EGB 7EGC 7EGD 7EGE 7EGF 7EGI 7EGJ 7ENA 7ENC 8GXQ 8GXS 8WAK 8WAL 8WAN 8WAO 8WAP 8WAQ 8WAR 8WAS	1F3U 1I27 1J2X 1NHA 1ONV 2K7L 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 6O9L 7EDX 7EG7 7EG8 7EG9 7EGA 7EGB 7EGC 7ENA 7ENC 7LBM 7NVR 7NVS 7NVT 7NVU 7NVY 7NVZ 7NW0 7ZWD 7ZX7 7ZX8 8BVW 8BYQ 8BZ1 8GXQ 8GXS 8S51 8S52 8S54 8S55 8S5N 8WAK 8WAL 8WAN 8WAO 8WAP 8WAQ 8WAR 8WAS 8WAT 8WAU 8WAV 8WAW 8WAX 8WAY 8WAZ 8WB0
Enriched GO Terms of Interacting Partners?		Transcription Factor TFIID Complex RNA Polymerase II General Transcription Initiation Factor Activity MRNA Transcription By RNA Polymerase II MRNA Transcription Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter DNA-templated Transcription Initiation DNA-templated Transcription RNA Polymerase II Preinitiation Complex Assembly Transcription Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Initiation Nucleobase-containing Compound Biosynthetic Process Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of DNA-templated Transcription Initiation Protein-DNA Complex Assembly RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Transcription Factor TFTC Complex Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Macromolecule Biosynthetic Process Positive Regulation Of RNA Metabolic Process MRNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process Nucleoplasm Protein Heterodimerization Activity Positive Regulation Of Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Biosynthetic Process DNA Binding Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Transcription Cis-regulatory Region Binding Regulation Of RNA Biosynthetic Process Macromolecule Metabolic Process Regulation Of RNA Metabolic Process Nucleus Positive Regulation Of Metabolic Process Protein-containing Complex Assembly Regulation Of Nucleobase-containing Compound Metabolic Process Protein-containing Complex Organization Regulation Of Vitamin D Receptor Signaling Pathway MLL1 Complex RNA Polymerase II Transcription Regulator Complex Regulation Of DNA Repair DNA-binding Transcription Factor Binding Male Germ Cell Nucleus	Transcription By RNA Polymerase II DNA-templated Transcription RNA Polymerase II General Transcription Initiation Factor Activity Transcription Initiation At RNA Polymerase II Promoter Nucleobase-containing Compound Biosynthetic Process Transcription Factor TFIID Complex DNA-templated Transcription Initiation RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of Transcription By RNA Polymerase II RNA Metabolic Process Nucleus Positive Regulation Of DNA-templated Transcription Initiation Nucleoplasm Host-mediated Activation Of Viral Transcription Regulation Of DNA-templated Transcription Initiation Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Macromolecule Biosynthetic Process RNA Polymerase II Core Promoter Sequence-specific DNA Binding Positive Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Transcription Regulator Complex Nucleic Acid Metabolic Process TBP-class Protein Binding Positive Regulation Of RNA Metabolic Process DNA Binding Host-mediated Perturbation Of Viral Transcription Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Host-mediated Activation Of Viral Process Regulation Of Nucleobase-containing Compound Metabolic Process Transcription Cis-regulatory Region Binding Positive Regulation Of MiRNA Transcription Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of MiRNA Metabolic Process Positive Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of Metabolic Process RNA Polymerase II General Transcription Initiation Factor Binding RNA Polymerase II Transcription Regulator Complex Positive Regulation Of Macromolecule Metabolic Process Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of MiRNA Transcription Host-mediated Perturbation Of Viral Process Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of DNA-templated Transcription
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