TAF11 and GTF2E1

Number of citations of the paper that reports this interaction (PubMedID 9159119)
32

Data Source:
BioGRID (pull down, biochemical)

		TAF11	GTF2E1
Description		TATA-box binding protein associated factor 11	general transcription factor IIE subunit 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor TFIID Complex Golgi Apparatus	Nucleus Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFIIE Complex Cytosol
	Molecular Function	Transcription Coactivator Activity Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity TBP-class Protein Binding Nuclear Vitamin D Receptor Binding Nuclear Thyroid Hormone Receptor Binding Protein Heterodimerization Activity	Protein Binding Zinc Ion Binding RNA Polymerase II General Transcription Initiation Factor Activity Metal Ion Binding
	Biological Process	Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter MRNA Transcription By RNA Polymerase II Host-mediated Activation Of Viral Transcription RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II	Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 34021172) Waist circumference adjusted for body mass index ( 34021172)	Obesity-related traits ( 23251661)
Interacting Genes		28 interacting genes: APP APPBP2 CPSF1 GTF2B GTF2E1 GTF2F1 H3-4 LZTR1 NFYA NFYB NFYC RELA RXRA RXRB TAF1 TAF10 TAF12 TAF13 TAF2 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9 TBP TRIM24 VDR	34 interacting genes: APP CBFA2T2 CDK7 ERCC2 ERCC3 GTF2A1 GTF2A2 GTF2B GTF2E2 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 IKBKG NRARP OGT PCBD2 SND1 SRPK2 TAF1 TAF11 TAF6 TBC1D21 TBP TCEA1 TLE5 TRIM15 TRIM24 TRIM29 ZBTB9 ZSCAN1
Entrez ID		6882	2960
HPRD ID		15980	01799
Ensembl ID		ENSG00000064995	ENSG00000153767
Uniprot IDs		Q15544	P29083
PDB IDs		1BH8 1BH9 6MZD 6MZL 7EDX 7EG7 7EG8 7EG9 7EGA 7EGB 7EGC 7EGD 7EGE 7EGF 7EGI 7EGJ 7ENA 7ENC 8GXQ 8GXS 8WAK 8WAL 8WAN 8WAO 8WAP 8WAQ 8WAR 8WAS	1VD4 2JTX 2RNQ 2RNR 5GPY 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 6O9L 7EG9 7EGA 7EGB 7EGC 7ENA 7ENC 7LBM 7NVR 7NVS 7NVT 7NVU 7NVV 7NVW 7NVX 7NVY 7NVZ 7NW0 8BVW 8BYQ 8GXQ 8GXS 8S51 8S52 8S54 8S55 8S5N 8WAK 8WAL 8WAN 8WAO 8WAP 8WAQ 8WAR 8WAS
Enriched GO Terms of Interacting Partners?		Transcription Factor TFIID Complex RNA Polymerase II General Transcription Initiation Factor Activity MRNA Transcription By RNA Polymerase II MRNA Transcription Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter DNA-templated Transcription Initiation DNA-templated Transcription RNA Polymerase II Preinitiation Complex Assembly Transcription Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Initiation Nucleobase-containing Compound Biosynthetic Process Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of DNA-templated Transcription Initiation Protein-DNA Complex Assembly RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Transcription Factor TFTC Complex Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Macromolecule Biosynthetic Process Positive Regulation Of RNA Metabolic Process MRNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process Nucleoplasm Protein Heterodimerization Activity Positive Regulation Of Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Biosynthetic Process DNA Binding Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Transcription Cis-regulatory Region Binding Regulation Of RNA Biosynthetic Process Macromolecule Metabolic Process Regulation Of RNA Metabolic Process Nucleus Positive Regulation Of Metabolic Process Protein-containing Complex Assembly Regulation Of Nucleobase-containing Compound Metabolic Process Protein-containing Complex Organization Regulation Of Vitamin D Receptor Signaling Pathway MLL1 Complex RNA Polymerase II Transcription Regulator Complex Regulation Of DNA Repair DNA-binding Transcription Factor Binding Male Germ Cell Nucleus	Transcription Factor TFIID Complex Transcription Initiation At RNA Polymerase II Promoter DNA-templated Transcription Initiation Transcription By RNA Polymerase II RNA Polymerase II General Transcription Initiation Factor Activity DNA-templated Transcription Transcription Factor TFIIH Core Complex Transcription Factor TFIIH Holo Complex Nucleobase-containing Compound Biosynthetic Process RNA Metabolic Process Macromolecule Biosynthetic Process Nucleic Acid Metabolic Process Regulation Of RNA Metabolic Process RNA Polymerase II General Transcription Initiation Factor Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase II Preinitiation Complex Assembly Nucleobase-containing Compound Metabolic Process DNA-templated Transcription Elongation Nucleotide-excision Repair Transcription Preinitiation Complex Assembly Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription By RNA Polymerase II TBP-class Protein Binding Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of Transcription Initiation By RNA Polymerase II Protein-DNA Complex Assembly Nucleus Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Macromolecule Metabolic Process Positive Regulation Of DNA-templated Transcription Initiation Core TFIIH Complex Portion Of Holo TFIIH Complex Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of Nucleobase-containing Compound Metabolic Process Transcription Preinitiation Complex Nucleoplasm Positive Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Initiation Transcription Elongation By RNA Polymerase II Regulation Of Metabolic Process Transcription Factor TFIIA Complex RNA Polymerase II Core Promoter Sequence-specific DNA Binding Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process
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