TAF4 and CBX3

Number of citations of the paper that reports this interaction (PMID 11959914)
20

Data Source:
HPRD (two hybrid, in vitro)

		TAF4	CBX3
Gene Name		TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa	chromobox homolog 3
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Gene Ontology Annotations	Cellular Component	Nucleoplasm Transcription Factor TFIID Complex Cytoplasm Transcription Factor TFTC Complex MLL1 Complex	Condensed Chromosome, Centromeric Region Chromatin Nucleus Nuclear Envelope Nuclear Inner Membrane Nucleoplasm Nuclear Euchromatin Nuclear Heterochromatin Spindle Nuclear Pericentric Heterochromatin
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Protein Heterodimerization Activity	Protein Binding Enzyme Binding Protein Domain Specific Binding Identical Protein Binding Histone Methyltransferase Binding
	Biological Process	Ovarian Follicle Development DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process Positive Regulation Of Transcription, DNA-templated	Chromatin Remodeling Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Rhythmic Process
Pathways		RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome	RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription
Drugs
Diseases
GWAS
Protein-Protein Interactions		22 interactors: AHR ATF7 CBX3 CBX5 CREM GTF2A1 GTF2A2 HIST3H3 HTT JUN SP1 TAF1 TAF10 TAF11 TAF12 TAF2 TAF5 TAF6 TAF7 TAF8 TAF9 TCF12	32 interactors: ARL5A ATXN7L2 AURKA AURKB CACNB4 CBX1 CBX5 DNMT3B DSN1 H3F3A HIST1H1E HIST1H3A HIST1H4A HIST3H3 KLF11 L3MBTL1 L3MBTL2 LBR MGA MIS12 MKI67 NIPBL NSL1 PIM1 SP100 TAF4 TRIM24 TRIM28 VHL WHSC1L1 ZNF10 ZNF496
Entrez ID		6874	11335
HPRD ID		11797	05130
Ensembl ID		ENSG00000130699	ENSG00000122565
Uniprot IDs		O00268	A4D177 B8ZZ43 Q13185
PDB IDs		1H3O 2P6V	2L11 3DM1 3KUP 3TZD
Enriched GO Terms of Interacting Partners?		Transcription Elongation From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Viral Process RNA Metabolic Process Heterocycle Metabolic Process Regulation Of Gene Expression Gene Expression Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Positive Regulation By Host Of Viral Transcription Internal Protein Amino Acid Acetylation Protein Acetylation Regulation Of Transcription From RNA Polymerase II Promoter Cellular Metabolic Process Rhythmic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process RNA Polymerase II Transcriptional Preinitiation Complex Assembly Peptidyl-lysine Modification Interaction With Symbiont Regulation Of Cellular Process Histone H3 Acetylation Positive Regulation Of Viral Transcription Chromatin Modification Circadian Rhythm Chromosome Organization	Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Chromosome Organization Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Chromatin Organization Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated DNA Methylation On Cytosine Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of RNA Metabolic Process DNA Methylation Regulation Of Nitrogen Compound Metabolic Process Chromatin Modification Organelle Organization DNA Modification Chromatin Silencing Mitotic Cell Cycle Chromatin Silencing At RDNA Mitotic Cell Cycle Process Protein-DNA Complex Assembly Mitotic Nuclear Division Negative Regulation Of Gene Expression, Epigenetic Cell Cycle Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Gene Expression Regulation Of Gene Expression, Epigenetic Protein Autophosphorylation Nucleobase-containing Compound Metabolic Process Spindle Stabilization Gene Silencing Chromosome Segregation Methylation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nucleosome Assembly Nitrogen Compound Metabolic Process Chromatin Assembly Cellular Nitrogen Compound Metabolic Process Protein Complex Assembly Nucleosome Organization Cell Cycle Process Chromatin Assembly Or Disassembly DNA Replication-dependent Nucleosome Assembly Transcription, DNA-templated DNA Packaging
Tagcloud ?		adjacent characterised directed directing elements embryonic hepatocyte heterodimer highlighting hnf4a inactivation instructive interacts maintain maturation mutually natal occupancy pausing pic post promotes proximal start subset taf12 tafs tfiid	1gamma actively assembled biogenesis deformed depleted dnmt3a h3k27 h3k9 heterochromatin hp1gamma linker npm1 nucleolar nucleoli nucleolus organization organized organizer perinucleolar rdna repetitive repressive ribosome silver striking tethering trimethylated u1242mg
Tagcloud (Difference) ?		adjacent characterised directed directing elements embryonic hepatocyte heterodimer highlighting hnf4a inactivation instructive interacts maintain maturation mutually natal occupancy pausing pic post promotes proximal start subset taf12 tafs tfiid	1gamma actively assembled biogenesis deformed depleted dnmt3a h3k27 h3k9 heterochromatin hp1gamma linker npm1 nucleolar nucleoli nucleolus organization organized organizer perinucleolar rdna repetitive repressive ribosome silver striking tethering trimethylated u1242mg
Tagcloud (Intersection) ?