CBX3 and L3MBTL1

Number of citations of the paper that reports this interaction (PMID 17540172)
97

Data Source:
HPRD (in vivo, in vitro)

		CBX3	L3MBTL1
Gene Name		chromobox homolog 3	l(3)mbt-like 1 (Drosophila)
Image
Gene Ontology Annotations	Cellular Component	Condensed Chromosome, Centromeric Region Chromatin Nucleus Nuclear Envelope Nuclear Inner Membrane Nucleoplasm Nuclear Euchromatin Nuclear Heterochromatin Spindle Nuclear Pericentric Heterochromatin	Chromatin Condensed Chromosome Nucleus Nucleoplasm Nucleolus Plasma Membrane
	Molecular Function	Protein Binding Enzyme Binding Protein Domain Specific Binding Identical Protein Binding Histone Methyltransferase Binding	Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Zinc Ion Binding Nucleosome Binding Nucleosomal Histone Binding SAM Domain Binding Methylated Histone Binding Histone Binding Identical Protein Binding
	Biological Process	Chromatin Remodeling Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Rhythmic Process	Transcription, DNA-templated Regulation Of Mitotic Nuclear Division Chromatin Modification Hemopoiesis Regulation Of Megakaryocyte Differentiation Negative Regulation Of Transcription, DNA-templated Regulation Of Cell Cycle
Pathways		RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription
Drugs
Diseases
GWAS
Protein-Protein Interactions		32 interactors: ARL5A ATXN7L2 AURKA AURKB CACNB4 CBX1 CBX5 DNMT3B DSN1 H3F3A HIST1H1E HIST1H3A HIST1H4A HIST3H3 KLF11 L3MBTL1 L3MBTL2 LBR MGA MIS12 MKI67 NIPBL NSL1 PIM1 SP100 TAF4 TRIM24 TRIM28 VHL WHSC1L1 ZNF10 ZNF496	7 interactors: CBX3 ETV6 ETV7 HIST1H1B HIST4H4 RB1 SETD7
Entrez ID		11335	26013
HPRD ID		05130	16387
Ensembl ID		ENSG00000122565	ENSG00000185513
Uniprot IDs		A4D177 B8ZZ43 Q13185	Q9Y468
PDB IDs		2L11 3DM1 3KUP 3TZD	1OYX 1OZ2 1OZ3 2PQW 2RHI 2RHU 2RHX 2RHY 2RHZ 2RI2 2RI3 2RI5 2RJC 2RJD 2RJE 2RJF 3OQ5 3P8H 3UWN
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Chromosome Organization Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Chromatin Organization Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated DNA Methylation On Cytosine Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of RNA Metabolic Process DNA Methylation Regulation Of Nitrogen Compound Metabolic Process Chromatin Modification Organelle Organization DNA Modification Chromatin Silencing Mitotic Cell Cycle Chromatin Silencing At RDNA Mitotic Cell Cycle Process Protein-DNA Complex Assembly Mitotic Nuclear Division Negative Regulation Of Gene Expression, Epigenetic Cell Cycle Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Gene Expression Regulation Of Gene Expression, Epigenetic Protein Autophosphorylation Nucleobase-containing Compound Metabolic Process Spindle Stabilization Gene Silencing Chromosome Segregation Methylation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nucleosome Assembly Nitrogen Compound Metabolic Process Chromatin Assembly Cellular Nitrogen Compound Metabolic Process Protein Complex Assembly Nucleosome Organization Cell Cycle Process Chromatin Assembly Or Disassembly DNA Replication-dependent Nucleosome Assembly Transcription, DNA-templated DNA Packaging	Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Chromatin Organization Chromosome Organization Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Chromatin Modification Chromatin Remodeling Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Protein Localization To Chromosome Negative Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Transcription, DNA-templated RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleosome Assembly Negative Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Sister Chromatid Biorientation Chromatin Assembly Organelle Organization Nucleosome Organization RNA Metabolic Process Chromatin Assembly Or Disassembly Regulation Of Centromere Complex Assembly Histone H4-K20 Demethylation Negative Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Nitrogen Compound Metabolic Process Protein-DNA Complex Assembly Regulation Of Transcription From RNA Polymerase II Promoter Maintenance Of Mitotic Sister Chromatid Cohesion Regulation Of Cohesin Localization To Chromatin Regulation Of Myeloid Cell Differentiation DNA Packaging Cellular Macromolecule Biosynthetic Process Negative Regulation Of Megakaryocyte Differentiation Attachment Of Mitotic Spindle Microtubules To Kinetochore Macromolecule Biosynthetic Process Regulation Of Chromosome Organization Establishment Of Protein Localization To Chromatin
Tagcloud ?		1gamma actively assembled biogenesis deformed depleted dnmt3a h3k27 h3k9 heterochromatin hp1gamma linker npm1 nucleolar nucleoli nucleolus organization organized organizer perinucleolar rdna repetitive repressive ribosome silver striking tethering trimethylated u1242mg	advances alterations asxl1 discovery driving epigenetic existence idh1 idh2 jak leukemic modifiers modify modifying mpn mpns myeloproliferative neoplasms nevertheless predate predominant prmt5 reading reviews stat suspected technologies tet2 translational
Tagcloud (Difference) ?		1gamma actively assembled biogenesis deformed depleted dnmt3a h3k27 h3k9 heterochromatin hp1gamma linker npm1 nucleolar nucleoli nucleolus organization organized organizer perinucleolar rdna repetitive repressive ribosome silver striking tethering trimethylated u1242mg	advances alterations asxl1 discovery driving epigenetic existence idh1 idh2 jak leukemic modifiers modify modifying mpn mpns myeloproliferative neoplasms nevertheless predate predominant prmt5 reading reviews stat suspected technologies tet2 translational
Tagcloud (Intersection) ?