CBX3 and ATXN7L2

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CBX3	ATXN7L2
Gene Name		chromobox homolog 3	ataxin 7-like 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Condensed Chromosome, Centromeric Region Chromatin Nucleus Nuclear Envelope Nuclear Inner Membrane Nucleoplasm Nuclear Euchromatin Nuclear Heterochromatin Spindle Nuclear Pericentric Heterochromatin
	Molecular Function	Protein Binding Enzyme Binding Protein Domain Specific Binding Identical Protein Binding Histone Methyltransferase Binding
	Biological Process	Chromatin Remodeling Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Rhythmic Process
Pathways		RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription
Drugs
Diseases
GWAS			Chronic kidney disease ( 20383146) Major depressive disorder ( 20125088)
Protein-Protein Interactions		32 interactors: ARL5A ATXN7L2 AURKA AURKB CACNB4 CBX1 CBX5 DNMT3B DSN1 H3F3A HIST1H1E HIST1H3A HIST1H4A HIST3H3 KLF11 L3MBTL1 L3MBTL2 LBR MGA MIS12 MKI67 NIPBL NSL1 PIM1 SP100 TAF4 TRIM24 TRIM28 VHL WHSC1L1 ZNF10 ZNF496	4 interactors: CBX3 LAMB1 MDFI PPP2R3A
Entrez ID		11335	127002
HPRD ID		05130	12506
Ensembl ID		ENSG00000122565	ENSG00000162650
Uniprot IDs		A4D177 B8ZZ43 Q13185	I6L9B5 Q5T6C5
PDB IDs		2L11 3DM1 3KUP 3TZD
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Chromosome Organization Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Chromatin Organization Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated DNA Methylation On Cytosine Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of RNA Metabolic Process DNA Methylation Regulation Of Nitrogen Compound Metabolic Process Chromatin Modification Organelle Organization DNA Modification Chromatin Silencing Mitotic Cell Cycle Chromatin Silencing At RDNA Mitotic Cell Cycle Process Protein-DNA Complex Assembly Mitotic Nuclear Division Negative Regulation Of Gene Expression, Epigenetic Cell Cycle Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Gene Expression Regulation Of Gene Expression, Epigenetic Protein Autophosphorylation Nucleobase-containing Compound Metabolic Process Spindle Stabilization Gene Silencing Chromosome Segregation Methylation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nucleosome Assembly Nitrogen Compound Metabolic Process Chromatin Assembly Cellular Nitrogen Compound Metabolic Process Protein Complex Assembly Nucleosome Organization Cell Cycle Process Chromatin Assembly Or Disassembly DNA Replication-dependent Nucleosome Assembly Transcription, DNA-templated DNA Packaging	Neuronal-glial Interaction Involved In Cerebral Cortex Radial Glia Guided Migration Organ Morphogenesis Regulation Of Cell Motility Involved In Somitogenic Axis Elongation Negative Regulation Of Wnt Signaling Pathway Embryo Development Regulation Of Wnt Signaling Pathway Regulation Of Somitogenesis Wnt Signaling Pathway Involved In Somitogenesis Somatic Muscle Development Pattern Specification Process
Tagcloud ?		1gamma actively assembled biogenesis deformed depleted dnmt3a h3k27 h3k9 heterochromatin hp1gamma linker npm1 nucleolar nucleoli nucleolus organization organized organizer perinucleolar rdna repetitive repressive ribosome silver striking tethering trimethylated u1242mg
Tagcloud (Difference) ?		1gamma actively assembled biogenesis deformed depleted dnmt3a h3k27 h3k9 heterochromatin hp1gamma linker npm1 nucleolar nucleoli nucleolus organization organized organizer perinucleolar rdna repetitive repressive ribosome silver striking tethering trimethylated u1242mg
Tagcloud (Intersection) ?