TAF4 and TAF6

Number of citations of the paper that reports this interaction (PMID 14580349)
15

Data Source:
HPRD (in vivo, in vitro)

		TAF4	TAF6
Gene Name		TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Transcription Factor TFIID Complex Cytoplasm Transcription Factor TFTC Complex MLL1 Complex	Nucleus Nucleoplasm Transcription Factor TFIID Complex Cytoplasm Transcription Factor TFTC Complex MLL1 Complex
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Protein Heterodimerization Activity	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Heterodimerization Activity
	Biological Process	Ovarian Follicle Development DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process Positive Regulation Of Transcription, DNA-templated	DNA-templated Transcription, Initiation Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Cell Proliferation Gene Expression Viral Process Negative Regulation Of Cell Cycle Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Pathways		RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome	RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome
Drugs
Diseases
GWAS
Protein-Protein Interactions		22 interactors: AHR ATF7 CBX3 CBX5 CREM GTF2A1 GTF2A2 HIST3H3 HTT JUN SP1 TAF1 TAF10 TAF11 TAF12 TAF2 TAF5 TAF6 TAF7 TAF8 TAF9 TCF12	24 interactors: AHR APP CIITA GTF2E1 HIST3H3 HNF4A NCOR1 NFYA NFYB NFYC NR1D2 RELA SH3KBP1 TAF1 TAF10 TAF11 TAF12 TAF2 TAF4 TAF5 TAF7 TAF8 TAF9 TAF9B
Entrez ID		6874	6878
HPRD ID		11797	11807
Ensembl ID		ENSG00000130699	ENSG00000106290
Uniprot IDs		O00268	P49848
PDB IDs		1H3O 2P6V
Enriched GO Terms of Interacting Partners?		Transcription Elongation From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Viral Process RNA Metabolic Process Heterocycle Metabolic Process Regulation Of Gene Expression Gene Expression Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Positive Regulation By Host Of Viral Transcription Internal Protein Amino Acid Acetylation Protein Acetylation Regulation Of Transcription From RNA Polymerase II Promoter Cellular Metabolic Process Rhythmic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process RNA Polymerase II Transcriptional Preinitiation Complex Assembly Peptidyl-lysine Modification Interaction With Symbiont Regulation Of Cellular Process Histone H3 Acetylation Positive Regulation Of Viral Transcription Chromatin Modification Circadian Rhythm Chromosome Organization	Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Transcription Elongation From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Viral Process Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway Cellular Metabolic Process Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Regulation Of Cellular Process Peptidyl-lysine Modification Rhythmic Process Histone H3 Acetylation Chromatin Modification Metabolic Process Histone Modification Chromosome Organization Chromatin Organization Negative Regulation Of Transcription, DNA-templated
Tagcloud ?		adjacent characterised directed directing elements embryonic hepatocyte heterodimer highlighting hnf4a inactivation instructive interacts maintain maturation mutually natal occupancy pausing pic post promotes proximal start subset taf12 tafs tfiid	acting alternative choice cis comparative decisions define depletion dictate drives elements employ gain inducible microarray minigene modulate mutational nothing pivotal pol splice splicing taf6alpha taf6delta tfiid transcriptome triggering undefined
Tagcloud (Difference) ?		adjacent characterised directed directing embryonic hepatocyte heterodimer highlighting hnf4a inactivation instructive interacts maintain maturation mutually natal occupancy pausing pic post promotes proximal start subset taf12 tafs	acting alternative choice cis comparative decisions define depletion dictate drives employ gain inducible microarray minigene modulate mutational nothing pivotal pol splice splicing taf6alpha taf6delta transcriptome triggering undefined
Tagcloud (Intersection) ?		elements tfiid