TAF1 and EDF1

Number of citations of the paper that reports this interaction (PMID 12040021)
10

Data Source:
HPRD (in vitro)

		TAF1	EDF1
Gene Name		TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa	endothelial differentiation-related factor 1
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Transcription Factor TFIID Complex MLL1 Complex	Intracellular Nucleus Transcription Factor TFIID Complex Nucleolus Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	P53 Binding Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Transcription Factor Binding TBP-class Protein Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Lysine-acetylated Histone Binding	Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding Calmodulin Binding Methyltransferase Activity Sequence-specific DNA Binding Poly(A) RNA Binding
	Biological Process	DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Cellular Response To DNA Damage Stimulus Cell Cycle Gene Expression Viral Process Histone Acetylation Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Autophosphorylation RNA Polymerase II Transcriptional Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Multicellular Organismal Development Regulation Of Lipid Metabolic Process Positive Regulation Of DNA Binding Endothelial Cell Differentiation Positive Regulation Of Transcription, DNA-templated
Pathways		RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome
Drugs
Diseases
GWAS
Protein-Protein Interactions		47 interactors: APC AR ASF1A ASF1B BRMS1 CCNA2 CCND1 EDF1 EWSR1 FOS GFI1B GTF2A1 GTF2E1 GTF2F1 HIST1H3A HIST1H4A HIST3H3 HMGB1 HSF1 JUN MAX MDM2 MSX1 PAX3 RANBP2 RB1 RBL1 RBL2 RELA SUB1 TAF10 TAF11 TAF12 TAF15 TAF2 TAF4 TAF4B TAF5 TAF6 TAF7 TAF7L TAF8 TAF9 TBP TP53 UBE2I UBTF	20 interactors: ATF1 ATF2 CALM1 CALM2 CALM3 CEBPA CREB1 JUN MAPK6 MEOX2 NR1H3 NR5A1 NR5A2 NRL PPARG PRKCA RXRA TAF1 TBP UBE2I
Entrez ID		6872	8721
HPRD ID		02436	09235
Ensembl ID		ENSG00000147133	ENSG00000107223
Uniprot IDs		P21675	O60869
PDB IDs		1EQF 3AAD 3UV4 3UV5	1X57
Enriched GO Terms of Interacting Partners?		RNA Biosynthetic Process Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Gene Expression Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Regulation Of Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process DNA-templated Transcription, Elongation Transcription Elongation From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Viral Process Regulation Of Metabolic Process Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Metabolic Process Chromatin Organization Positive Regulation Of Cellular Metabolic Process Chromosome Organization Positive Regulation Of Metabolic Process Negative Regulation Of Gene Expression Chromatin Modification Regulation Of Cellular Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Organelle Organization Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity DNA Replication-dependent Nucleosome Assembly Mitotic Cell Cycle	Positive Regulation Of Cellular Biosynthetic Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Response To Organic Cyclic Compound Response To Steroid Hormone Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Lipase Activity Response To Metal Ion Transcription, DNA-templated Cellular Response To Organic Substance RNA Biosynthetic Process Response To Lipid DNA-templated Transcription, Initiation Activation Of Phospholipase C Activity Response To Hormone Positive Regulation Of Phospholipase C Activity Gene Expression Response To Inorganic Substance Regulation Of Metabolic Process Organ Development Positive Regulation Of Phospholipase Activity Regulation Of Rhodopsin Mediated Signaling Pathway Innate Immune Response Response To Organic Substance Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Activation Of Adenylate Cyclase Activity Nitrogen Compound Metabolic Process Regulation Of Phospholipase Activity RNA Metabolic Process Regulation Of Protein Autophosphorylation Regulation Of Immune Response Steroid Hormone Mediated Signaling Pathway Rhodopsin Mediated Signaling Pathway Negative Regulation Of Cellular Metabolic Process Regulation Of High Voltage-gated Calcium Channel Activity Neurotrophin TRK Receptor Signaling Pathway Mitochondrion Organization Positive Regulation Of Adenylate Cyclase Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Neurotrophin Signaling Pathway Regulation Of Immune System Process System Development Defense Response
Tagcloud ?		3d acetyltransferase acetyltransferases architecture assembly cofolding displays dissociable ensures heterodimer integral lys27 machinery mark marks multiprotein neighboring nucleates obvious pic pockets preinitiation reading similarities taf7 tata tfiid trimethylated	2e 3e 8e abstracts asco auc btg2 candidates cxcl10 cyp2d6 dataset datasets downloaded drg1 ega geo hoxb7 mapk1 mapt pgr platforms rfs rnaseq sabcs slc7a5 tamoxifen tcga tpm4 transcriptomic
Tagcloud (Difference) ?		3d acetyltransferase acetyltransferases architecture assembly cofolding displays dissociable ensures heterodimer integral lys27 machinery mark marks multiprotein neighboring nucleates obvious pic pockets preinitiation reading similarities taf7 tata tfiid trimethylated	2e 3e 8e abstracts asco auc btg2 candidates cxcl10 cyp2d6 dataset datasets downloaded drg1 ega geo hoxb7 mapk1 mapt pgr platforms rfs rnaseq sabcs slc7a5 tamoxifen tcga tpm4 transcriptomic
Tagcloud (Intersection) ?