TAF1 and TAF2

Number of citations of the paper that reports this interaction (PMID 10469661)
65

Data Source:
HPRD (in vivo, in vitro)

		TAF1	TAF2
Gene Name		TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa	TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Transcription Factor TFIID Complex MLL1 Complex	Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFTC Complex
	Molecular Function	P53 Binding Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Transcription Factor Binding TBP-class Protein Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Lysine-acetylated Histone Binding	Protein Binding Metallopeptidase Activity Zinc Ion Binding Transcription Regulatory Region DNA Binding
	Biological Process	DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Cellular Response To DNA Damage Stimulus Cell Cycle Gene Expression Viral Process Histone Acetylation Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Autophosphorylation RNA Polymerase II Transcriptional Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter	G2/M Transition Of Mitotic Cell Cycle Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Proteolysis Gene Expression Response To Organic Cyclic Compound Viral Process Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome	RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome
Drugs
Diseases
GWAS
Protein-Protein Interactions		47 interactors: APC AR ASF1A ASF1B BRMS1 CCNA2 CCND1 EDF1 EWSR1 FOS GFI1B GTF2A1 GTF2E1 GTF2F1 HIST1H3A HIST1H4A HIST3H3 HMGB1 HSF1 JUN MAX MDM2 MSX1 PAX3 RANBP2 RB1 RBL1 RBL2 RELA SUB1 TAF10 TAF11 TAF12 TAF15 TAF2 TAF4 TAF4B TAF5 TAF6 TAF7 TAF7L TAF8 TAF9 TBP TP53 UBE2I UBTF	13 interactors: ESR1 HIST3H3 RNPS1 TAF1 TAF10 TAF11 TAF12 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9
Entrez ID		6872	6873
HPRD ID		02436	07060
Ensembl ID		ENSG00000147133	ENSG00000064313
Uniprot IDs		P21675	B3KMD8 Q6P1X5
PDB IDs		1EQF 3AAD 3UV4 3UV5
Enriched GO Terms of Interacting Partners?		RNA Biosynthetic Process Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Gene Expression Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Regulation Of Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process DNA-templated Transcription, Elongation Transcription Elongation From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Viral Process Regulation Of Metabolic Process Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Metabolic Process Chromatin Organization Positive Regulation Of Cellular Metabolic Process Chromosome Organization Positive Regulation Of Metabolic Process Negative Regulation Of Gene Expression Chromatin Modification Regulation Of Cellular Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Organelle Organization Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity DNA Replication-dependent Nucleosome Assembly Mitotic Cell Cycle	Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Transcription Elongation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Viral Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Nitrogen Compound Metabolic Process Protein Acetylation Regulation Of RNA Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Peptidyl-lysine Modification Chromosome Organization Regulation Of Transcription, DNA-templated Chromatin Modification Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Chromatin Organization Histone Modification Histone H3 Acetylation Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Metabolic Process Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Intracellular Estrogen Receptor Signaling Pathway Peptidyl-amino Acid Modification Positive Regulation Of Cellular Metabolic Process Organelle Organization Spermine Transport Ovarian Follicle Development Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Intracellular Steroid Hormone Receptor Signaling Pathway Metabolic Process
Tagcloud ?		3d acetyltransferase acetyltransferases architecture assembly cofolding displays dissociable ensures heterodimer integral lys27 machinery mark marks multiprotein neighboring nucleates obvious pic pockets preinitiation reading similarities taf7 tata tfiid trimethylated	cascades chemoresistance cofactor compose d2 dedifferentiation deleted deregulation directs drive execute expand granulosa helps hgsc initiator outline ovarian ovary paralog pluripotent serous strikingly taf4 taf4b taf9 tafs tata tfiid
Tagcloud (Difference) ?		3d acetyltransferase acetyltransferases architecture assembly cofolding displays dissociable ensures heterodimer integral lys27 machinery mark marks multiprotein neighboring nucleates obvious pic pockets preinitiation reading similarities taf7 trimethylated	cascades chemoresistance cofactor compose d2 dedifferentiation deleted deregulation directs drive execute expand granulosa helps hgsc initiator outline ovarian ovary paralog pluripotent serous strikingly taf4 taf4b taf9 tafs
Tagcloud (Intersection) ?		tata tfiid