EDF1 and CEBPA

Number of citations of the paper that reports this interaction (PMID 16880509)
14

Data Source:
BioGRID (pull down)

		EDF1	CEBPA
Gene Name		endothelial differentiation-related factor 1	CCAAT/enhancer binding protein (C/EBP), alpha
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Nucleus Transcription Factor TFIID Complex Nucleolus Cytoplasm Extracellular Vesicular Exosome	Nucleus Nuclear Matrix Rb-E2F Complex
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding Calmodulin Binding Methyltransferase Activity Sequence-specific DNA Binding Poly(A) RNA Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Factor Binding Protein Complex Binding Protein Homodimerization Activity Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity HMG Box Domain Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Multicellular Organismal Development Regulation Of Lipid Metabolic Process Positive Regulation Of DNA Binding Endothelial Cell Differentiation Positive Regulation Of Transcription, DNA-templated	Urea Cycle Negative Regulation Of Transcription From RNA Polymerase II Promoter Liver Development Embryonic Placenta Development Generation Of Precursor Metabolites And Energy Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Acute-phase Response Mitochondrion Organization Cholesterol Metabolic Process Negative Regulation Of Cell Proliferation Viral Process Cytokine-mediated Signaling Pathway Myeloid Cell Differentiation Macrophage Differentiation Lung Development Organ Regeneration Response To Vitamin B2 Positive Regulation Of Fat Cell Differentiation Positive Regulation Of Osteoblast Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase III Promoter Cell Maturation Inner Ear Development White Fat Cell Differentiation Brown Fat Cell Differentiation Response To Glucocorticoid Cellular Response To Lithium Ion Cellular Response To Organic Cyclic Compound
Pathways			Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS
Protein-Protein Interactions		20 interactors: ATF1 ATF2 CALM1 CALM2 CALM3 CEBPA CREB1 JUN MAPK6 MEOX2 NR1H3 NR5A1 NR5A2 NRL PPARG PRKCA RXRA TAF1 TBP UBE2I	56 interactors: AR ATF2 ATF3 ATF4 ATF5 BATF BATF2 BATF3 C1QBP CDK2 CDK4 CDKN1A CDKN3 CDX1 CEBPB CEBPD CEBPE CEBPG CREBBP CTNNB1 DBP EDF1 EP300 ESR1 FOS FOSL1 GATA2 GSK3B HNF1A MAPK8 MSX2 MYC NCOA6 NFYA NR3C1 PIAS1 RARA RARB RASGRF1 RB1 RBL1 RFC1 RUNX1 SKP2 SMAD3 SMAD4 SMARCA2 SMARCA4 SOX10 SOX8 SPI1 SRA1 SUMO3 XRCC5 XRCC6 ZBTB16
Entrez ID		8721	1050
HPRD ID		09235	00296
Ensembl ID		ENSG00000107223	ENSG00000245848
Uniprot IDs		O60869	P49715
PDB IDs		1X57
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cellular Biosynthetic Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Response To Organic Cyclic Compound Response To Steroid Hormone Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Lipase Activity Response To Metal Ion Transcription, DNA-templated Cellular Response To Organic Substance RNA Biosynthetic Process Response To Lipid DNA-templated Transcription, Initiation Activation Of Phospholipase C Activity Response To Hormone Positive Regulation Of Phospholipase C Activity Gene Expression Response To Inorganic Substance Regulation Of Metabolic Process Organ Development Positive Regulation Of Phospholipase Activity Regulation Of Rhodopsin Mediated Signaling Pathway Innate Immune Response Response To Organic Substance Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Activation Of Adenylate Cyclase Activity Nitrogen Compound Metabolic Process Regulation Of Phospholipase Activity RNA Metabolic Process Regulation Of Protein Autophosphorylation Regulation Of Immune Response Steroid Hormone Mediated Signaling Pathway Rhodopsin Mediated Signaling Pathway Negative Regulation Of Cellular Metabolic Process Regulation Of High Voltage-gated Calcium Channel Activity Neurotrophin TRK Receptor Signaling Pathway Mitochondrion Organization Positive Regulation Of Adenylate Cyclase Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Neurotrophin Signaling Pathway Regulation Of Immune System Process System Development Defense Response	Positive Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Transcription, DNA-templated Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Macromolecule Biosynthetic Process Gene Expression Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Metabolic Process Cellular Nitrogen Compound Metabolic Process Biosynthetic Process Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Organ Development Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated System Development Multicellular Organismal Development Cellular Metabolic Process Anatomical Structure Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Developmental Process Negative Regulation Of Cellular Metabolic Process Regulation Of Cellular Process Cell Differentiation Regulation Of Cell Proliferation Regulation Of Cell Differentiation Tissue Development Myeloid Cell Differentiation Positive Regulation Of Cell Differentiation Regulation Of Cell Death Transcription Initiation From RNA Polymerase II Promoter
Tagcloud ?		2e 3e 8e abstracts asco auc btg2 candidates cxcl10 cyp2d6 dataset datasets downloaded drg1 ega geo hoxb7 mapk1 mapt pgr platforms rfs rnaseq sabcs slc7a5 tamoxifen tcga tpm4 transcriptomic	acting additive c38 c40 caat cebpb collectively commitment composed concert elusive embryonic enhancer epidermis evolutionary fate keratinocyte keratinocytes layer modules p63 p63lre partly pluripotent pou pou3f1 redundant repress robust
Tagcloud (Difference) ?		2e 3e 8e abstracts asco auc btg2 candidates cxcl10 cyp2d6 dataset datasets downloaded drg1 ega geo hoxb7 mapk1 mapt pgr platforms rfs rnaseq sabcs slc7a5 tamoxifen tcga tpm4 transcriptomic	acting additive c38 c40 caat cebpb collectively commitment composed concert elusive embryonic enhancer epidermis evolutionary fate keratinocyte keratinocytes layer modules p63 p63lre partly pluripotent pou pou3f1 redundant repress robust
Tagcloud (Intersection) ?