TADA3 and CCNC

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		TADA3	CCNC
Description		transcriptional adaptor 3	cyclin C
Image		No pdb structure
GO Annotations	Cellular Component	SAGA Complex Nucleus Nucleoplasm Transcription Factor TFTC Complex Mitotic Spindle ATAC Complex	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleus Nucleoplasm Mediator Complex CKM Complex
	Molecular Function	Transcription Coactivator Activity Protein Binding Nuclear Receptor Binding Protein Domain Specific Binding	Protein Binding Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Mitotic Cell Cycle Regulation Of DNA Repair Chromatin Organization Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Estrogen Receptor Signaling Pathway Regulation Of Protein Stability Regulation Of RNA Splicing Positive Regulation Of DNA-templated Transcription Regulation Of Embryonic Development Regulation Of Cell Division Regulation Of Cell Cycle	Regulation Of Transcription By RNA Polymerase II G0 To G1 Transition Negative Regulation Of Notch Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II
Pathways		HATs acetylate histones Ub-specific processing proteases Formation of WDR5-containing histone-modifying complexes	PPARA activates gene expression NOTCH1 Intracellular Domain Regulates Transcription Generic Transcription Pathway SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation RSV-host interactions MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Drugs
Diseases
GWAS			Daytime nap ( 33568662) Erectile dysfunction ( 30297428) Longevity (100 years and older) ( 33948810) Refractive error ( 32231278)
Interacting Genes		35 interacting genes: ADPGK ANKRD12 ANKRD36B AR CCNC CEBPA CENPB EIF3J EP300 ESR1 FAM107B H3-4 HEXIM2 HSPA8 ING5 KDM1A MAGEH1 MFHAS1 NR1I2 OGT PIAS4 RARA RFX1 RXRA RXRB SAP18 SGF29 STX11 TADA2A TP53 TXLNB TXNRD2 USP5 XRCC6 ZNF7	79 interacting genes: ASH2L BLOC1S2 BTBD2 CCHCR1 CCNH CDK3 CDK8 CDKN2B CFAP53 CKS1B CRX DYDC1 ERCC3 ESR2 FAM161A FAM50B FAM90A1 FOXP2 FOXR2 GADD45GIP1 GLYR1 GOLGA2 GPC4 HACE1 HSPB1 ISY1 KRT13 KRT15 KRT16 KRT27 KRT31 KRT34 LCN2 LZTS2 MBD3 MBIP MCM2 MED8 MEOX2 MGST3 MYO15B NDUFB7 NEFL NMNAT1 NRBF2 PAX5 PLEKHO2 PLIN3 PNMA5 POU6F2 PRPF18 PUF60 RB1 RBM41 REL RFC5 RIBC1 RPA2 RUSC1 SERTAD3 SHC3 SPAG8 TADA3 TCEANC TEPSIN TEX12 TP63 TRAF3IP3 TRIM39 TRIM54 UBE2K VHL VTA1 ZFP90 ZNF18 ZNF426 ZNF620 ZNF688 ZNF792
Entrez ID		10474	892
HPRD ID		04252	00456
Ensembl ID		ENSG00000171148	ENSG00000112237
Uniprot IDs		A0A024R2D7 A8K899 O75528	E5RFK5 G5E954 P24863 Q7Z4L3
PDB IDs			3RGF 4CRL 4F6S 4F6U 4F6W 4F70 4F7J 4F7L 4F7N 4F7S 4G6L 5BNJ 5CEI 5FGK 5HBE 5HBH 5HBJ 5HNB 5HVY 5I5Z 5ICP 5IDN 5IDP 5XQX 5XS2 6QTG 6QTJ 6R3S 6T41 6TPA 6Y0A 8TQ2 8TQC 8TQW 9H8C 9H8S
Enriched GO Terms of Interacting Partners?		Regulation Of DNA-templated Transcription Negative Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Regulation Of RNA Metabolic Process Nuclear Receptor Activity Transcription Regulator Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Nucleoplasm Positive Regulation Of RNA Metabolic Process Chromatin Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Transcription Coactivator Binding Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nuclear Steroid Receptor Activity Retinoic Acid-responsive Element Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Chromatin Transcription Cis-regulatory Region Binding Chromatin DNA Binding DNA Binding Regulation Of Primary Metabolic Process Negative Regulation Of Metabolic Process Nucleus DNA-templated Transcription Nuclear Receptor-mediated Signaling Pathway Sequence-specific DNA Binding Cellular Response To Estrogen Stimulus DNA-binding Transcription Factor Activity Intracellular Receptor Signaling Pathway MRNA Transcription Response To Estrogen Regulation Of Macromolecule Metabolic Process Hormone-mediated Signaling Pathway Enzyme Binding Positive Regulation Of Macromolecule Biosynthetic Process Retinoic Acid Receptor Signaling Pathway Histone Acetyltransferase Complex Protein-containing Complex Regulation Of MiRNA Transcription	Nucleus Intermediate Filament Organization Protein Binding Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Keratin Filament Intermediate Filament DNA Binding Generation Of Catalytic Spliceosome For Second Transesterification Step Regulation Of Macromolecule Biosynthetic Process Cyclin-dependent Protein Kinase Holoenzyme Complex Regulation Of Macromolecule Metabolic Process Chromatin Cytoskeleton Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Structural Molecule Activity Axonemal A Tubule Inner Sheath Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Biosynthetic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Epithelial Cell Differentiation Epidermis Development Regulation Of Metabolic Process Importin-alpha Family Protein Binding Morphogenesis Of An Epithelium Regulation Of Mitotic Cell Cycle Phase Transition DNA-binding Transcription Factor Activity Regulation Of Cell Cycle Phase Transition Anterograde Axonal Transport
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