TAC3 and FEZ1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TAC3	FEZ1
Gene Name		tachykinin 3	fasciculation and elongation protein zeta 1 (zygin I)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Vesicular Exosome	Cytoplasm Mitochondrion Centrosome Microtubule Plasma Membrane Microtubule Cytoskeleton Axon Dendrite
	Molecular Function	Receptor Binding Protein Binding	Protein Kinase C Binding Protein Binding Gamma-tubulin Binding Protein N-terminus Binding
	Biological Process	Tachykinin Receptor Signaling Pathway Neuropeptide Signaling Pathway Female Pregnancy	Transport Cell Adhesion Nervous System Development Axon Guidance Positive Regulation Of Neuron Projection Development Establishment Of Mitochondrion Localization Cellular Response To Growth Factor Stimulus
Pathways		G alpha (q) signalling events G alpha (q) signalling events Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Tachykinin receptors bind tachykinins Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS			Schizophrenia ( 22688191 23894747)
Protein-Protein Interactions		10 interactors: CCDC90B FEZ1 GPRASP1 IKBKAP PTN TACR1 TACR2 TACR3 UBC UBR1	57 interactors: BARD1 BORA BRD1 C16orf59 C8orf33 CCL7 CIB1 CLASP2 COL9A2 CSTF2 DIS3L2 DISC1 DNAAF5 DRAP1 FEZ2 GEMIN7 GTF2F1 HAP1 HTATSF1 HTT IMMT KIAA1377 LRIF1 MEST NBR1 NDUFB9 NEK1 OLFML3 P4HB PAM16 PDCD7 PRKCZ PTH PTN PTPRS RAB3GAP1 RAB3GAP2 RAI14 RIF1 SAP30L SCOC SERPINH1 SMARCD1 SMC3 SMEK2 STAR TAC3 TAF1D TAF9 TBC1D25 TLK2 TOMM20 TTR TXNDC9 UBE4B WWC1 ZNF251
Entrez ID		6866	9638
HPRD ID		08877	09212
Ensembl ID		ENSG00000166863	ENSG00000149557
Uniprot IDs		Q9UHF0	Q99689
PDB IDs		1P9F
Enriched GO Terms of Interacting Partners?		Tachykinin Receptor Signaling Pathway Positive Regulation Of Uterine Smooth Muscle Contraction Positive Regulation Of Smooth Muscle Contraction Regulation Of Smooth Muscle Contraction Operant Conditioning Neuropeptide Signaling Pathway Positive Regulation Of Vascular Permeability Learning Regulation Of Muscle Contraction Regulation Of Vascular Permeability Positive Regulation Of Blood Pressure Response To Morphine Learning Or Memory Response To Electrical Stimulus Excretion Cognition Blood Circulation Smooth Muscle Contraction Cellular Response To Stimulus Positive Regulation Of Acetylcholine Secretion, Neurotransmission Response To Abiotic Stimulus Single-organism Behavior Response To Ammonium Ion Negative Regulation Of Signaling Cellular Response To Leucine G-protein Coupled Receptor Catabolic Process Positive Regulation Of Synaptic Transmission Response To Estradiol Intestine Smooth Muscle Contraction Negative Regulation Of Luteinizing Hormone Secretion Angiotensin-mediated Drinking Behavior Smooth Muscle Contraction Involved In Micturition Synaptic Transmission Behavior Response To Organic Substance Response To Stimulus Response To Alkaloid Regulation Of Acetylcholine Secretion, Neurotransmission Positive Regulation Of Synaptic Transmission, Cholinergic Positive Regulation Of Saliva Secretion Regulation Of Blood Pressure Regulation Of Cellular Process Prolactin Secretion Negative Regulation Of Gonadotropin Secretion Regulation Of Synaptic Transmission, Cholinergic Response To Leucine Regulation Of Saliva Secretion Micturition Response To Ozone Endosomal Transport	Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization Organelle Organization Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Regulation Of Cellular Process Vesicle Transport Along Microtubule Cell Cycle Mitotic Cell Cycle Microtubule-based Process Microtubule Cytoskeleton Organization Regulation Of Metabolic Process Response To Radiation Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Heterocycle Metabolic Process Cellular Process Cellular Homeostasis Organelle Transport Along Microtubule Positive Regulation Of Metabolic Process Response To Ionizing Radiation Response To Stimulus Movement Of Cell Or Subcellular Component Cell Division Regulation Of Intracellular Signal Transduction Cell Cycle Process Regulation Of Synaptic Plasticity Nucleobase-containing Compound Metabolic Process Cellular Response To DNA Damage Stimulus Regulation Of Synaptic Transmission Regulation Of Microtubule-based Process Response To Abiotic Stimulus Cellular Nitrogen Compound Metabolic Process Establishment Or Maintenance Of Cell Polarity Cellular Metabolic Process Mitotic Nuclear Division Mitotic Cell Cycle Process Homeostatic Process Regulation Of Signal Transduction Regulation Of Signaling Mitochondrial Calcium Ion Homeostasis Regulation Of Organelle Organization Cellular Aromatic Compound Metabolic Process Regulation Of Cellular Component Organization Nitrogen Compound Metabolic Process DNA-templated Transcription, Elongation Establishment Of Protein Localization To Organelle Anatomical Structure Development Nervous System Development RNA Metabolic Process Diencephalon Development Transcription, DNA-templated
Tagcloud ?		bioinformatics cichlids dispersed fsh fxglm gonadotropin holds isoleucine lh luc neurokinin nh2 nkb nkbs nkf piscine pituitary possess possessing reproduction sre tac3r tac3ra tac3rb tachikinin tilapia tinkb tinkf valine	atf5 burden credible disc1 disordered endophenotypes highlighting intriguing intrinsically lis maf missense nde1 ndel1 neuropsychiatric partners pde4b psychiatric reside schizophrenia striking swedish synonymous sz traf3ip1 unexplored variants ywhae znf365
Tagcloud (Difference) ?		bioinformatics cichlids dispersed fsh fxglm gonadotropin holds isoleucine lh luc neurokinin nh2 nkb nkbs nkf piscine pituitary possess possessing reproduction sre tac3r tac3ra tac3rb tachikinin tilapia tinkb tinkf valine	atf5 burden credible disc1 disordered endophenotypes highlighting intriguing intrinsically lis maf missense nde1 ndel1 neuropsychiatric partners pde4b psychiatric reside schizophrenia striking swedish synonymous sz traf3ip1 unexplored variants ywhae znf365
Tagcloud (Intersection) ?